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Yan W. Asmann

Yan W. Asmann

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
15614
World Ranking
7835
National Ranking
3562

Overview

Yan W. Asmann is affiliated with the Mayo Clinic in the United States and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work spans several subfields, including molecular biology, neurology, genetics, oncology, and physiology.

Their research focuses on topics such as:

  • Alzheimer's disease research and treatments
  • Neuroinflammation and neurodegeneration mechanisms
  • Multiple myeloma research and treatments
  • Bioinformatics and genomic networks
  • Glioma diagnosis and treatment
  • Protein degradation and inhibitors
  • Cancer genomics and diagnostics

Yan W. Asmann has published regularly in prominent scientific journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • Nature Communications
  • Molecular Neurodegeneration
  • Acta Neuropathologica

Among their recent papers are:

  • "APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids," 2020, Nature Communications
  • "Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways," 2020, Neuron
  • "APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid," 2020, Science Translational Medicine
  • "Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function," 2022, Nature Neuroscience
  • "Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia," 2022, The Journal of Experimental Medicine

Yan W. Asmann has collaborated frequently with several researchers, including:

  • Yingxue Ren
  • Nilüfer Ertekin-Taner
  • Guojun Bu
  • Dennis W. Dickson
  • Xue Wang

Best Publications

  • Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

    Jens G. Lohr;Petar Stojanov;Petar Stojanov;Michael S. Lawrence;Daniel Auclair

  • Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides

    Jan B. Egan;Chang Xin Shi;Waibhav Tembe;Alexis Christoforides

  • Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases

    Mariet Allen;Minerva M. Carrasquillo;Cory Funk;Benjamin D. Heavner

  • A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer

    Timothy K. Starr;Raha Allaei;Kevin A. T. Silverstein;Rodney A. Staggs

  • Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma

    Mitesh J. Borad;Mia D. Champion;Jan B. Egan;Winnie S. Liang

  • APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids

    Jing Zhao;Yuan Fu;Yu Yamazaki;Yingxue Ren

  • MAP-RSeq: Mayo Analysis Pipeline for RNA sequencing

    Krishna R. Kalari;Asha A. Nair;Jaysheel D. Bhavsar;Daniel R. O'Brien

  • Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia

    Yan W. Asmann;Craig S. Stump;Kevin R. Short;Jill M. Coenen-Schimke

  • Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas

    George Vasmatzis;Sarah H. Johnson;Ryan A. Knudson;Rhett P. Ketterling

  • Chronic caloric restriction preserves mitochondrial function in senescence without increasing mitochondrial biogenesis.

    Ian R. Lanza;Piotrek Zabielski;Katherine A. Klaus;Dawn M. Morse

  • Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas

    Esteban D Braggio;Scott Van Wier;Juhi Ojha;Ellen McPhail

  • Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways.

    Na Zhao;Yingxue Ren;Yu Yamazaki;Wenhui Qiao

  • Genomic Analysis Reveals That Immune Function Genes Are Strongly Linked to Clinical Outcome in the North Central Cancer Treatment Group N9831 Adjuvant Trastuzumab Trial

    Edith A. Perez;E. Aubrey Thompson;Karla V. Ballman;S. Keith Anderson

  • Asian Indians Have Enhanced Skeletal Muscle Mitochondrial Capacity to Produce ATP in Association with Severe Insulin-Resistance

    K. Sreekumaran Nair;Maureen L. Bigelow;Yan W. Asmann;Lisa S. Chow

  • IAP antagonists induce anti-tumor immunity in multiple myeloma.

    Marta Chesi;Noweeda N Mirza;Victoria M Garbitt;Meaghen E Sharik

  • 3' tag digital gene expression profiling of human brain and universal reference RNA using Illumina Genome Analyzer

    Yan W. Asmann;Eric W. Klee;E. Aubrey Thompson;Edith A. Perez

  • A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q

    J. A. Heit;S. M. Armasu;Y. W. Asmann;J. M. Cunningham

  • A Tissue Biomarker Panel Predicting Systemic Progression after PSA Recurrence Post-Definitive Prostate Cancer Therapy

    Tohru Nakagawa;Thomas M. Kollmeyer;Bruce W. Morlan;S. Keith Anderson

  • Integrated analysis of gene expression, CpG island methylation, and gene copy number in breast cancer cells by deep sequencing.

    Zhifu Sun;Yan W. Asmann;Krishna R. Kalari;Brian Bot

  • miRNA Expression in Colon Polyps Provides Evidence for a Multihit Model of Colon Cancer

    Ann L. Oberg;Amy J. French;Aaron L. Sarver;Subbaya Subramanian

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