World's Best Scientists 2026 revealed!
David A. Largaespada

David A. Largaespada

D-Index & Metrics

Genetics

D-Index
76
Citations
34694
World Ranking
1795
National Ranking
823

David A. Largaespada publication distribution in Genetics in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Genetics in 2026. The highlighted bar marks where David A. Largaespada sits on this spectrum.

45–54 publications: 6 scientists 55–64 publications: 10 scientists 65–74 publications: 35 scientists 75–84 publications: 84 scientists 85–94 publications: 102 scientists 95–104 publications: 151 scientists 105–114 publications: 175 scientists 115–124 publications: 203 scientists 125–134 publications: 217 scientists 135–144 publications: 205 scientists 145–154 publications: 193 scientists 155–164 publications: 188 scientists 165–174 publications: 170 scientists 175–184 publications: 178 scientists 185–194 publications: 164 scientists 195–204 publications: 173 scientists 205–214 publications: 159 scientists 215–224 publications: 134 scientists 225–234 publications: 143 scientists 235–244 publications: 105 scientists 245–254 publications: 114 scientists 255–264 publications: 92 scientists 265–274 publications: 88 scientists 275–284 publications: 87 scientists 285–294 publications: 80 scientists 295–304 publications: 62 scientists 305–314 publications: 75 scientists 315–324 publications: 67 scientists 325–334 publications: 60 scientists 335–344 publications: 52 scientists 345–354 publications: 40 scientists 355–364 publications: 48 scientists 365–374 publications: 47 scientists 375–384 publications: 46 scientists 385–394 publications: 31 scientists 395–404 publications: 27 scientists 405–414 publications: 40 scientists 415–424 publications: 30 scientists 425–434 publications: 43 scientists 435–444 publications: 29 scientists 445–454 publications: 14 scientists 455–464 publications: 28 scientists 465–474 publications: 21 scientists 475–484 publications: 21 scientists 485–494 publications: 22 scientists 495–504 publications: 17 scientists 505–514 publications: 12 scientists 515–524 publications: 11 scientists 525–534 publications: 8 scientists 535–544 publications: 8 scientists 545–554 publications: 14 scientists 555–564 publications: 4 scientists 565–574 publications: 11 scientists 575–584 publications: 5 scientists 585–594 publications: 11 scientists 595–604 publications: 12 scientists 605–614 publications: 7 scientists 615–624 publications: 6 scientists 625–634 publications: 10 scientists 635–644 publications: 9 scientists 645–654 publications: 10 scientists 655–664 publications: 6 scientists 665–674 publications: 6 scientists 675–684 publications: 6 scientists 685–694 publications: 4 scientists 695–702 publications: 6 scientists 703+ publications: 100 scientists
45 publications 703+

This scientist: 368 publications — 85th percentile

85% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 703 publications or more.

David A. Largaespada D-index placement in Genetics in 2026

The chart shows the D-index (discipline H-index) distribution of Genetics scientists ranked by Research.com in 2026. The highlighted bar marks where David A. Largaespada sits on this spectrum.

40–41 D-Index: 24 scientists 42–43 D-Index: 52 scientists 44–45 D-Index: 84 scientists 46–47 D-Index: 112 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 141 scientists 52–53 D-Index: 143 scientists 54–55 D-Index: 145 scientists 56–57 D-Index: 179 scientists 58–59 D-Index: 162 scientists 60–61 D-Index: 175 scientists 62–63 D-Index: 191 scientists 64–65 D-Index: 172 scientists 66–67 D-Index: 184 scientists 68–69 D-Index: 164 scientists 70–71 D-Index: 158 scientists 72–73 D-Index: 150 scientists 74–75 D-Index: 136 scientists 76–77 D-Index: 127 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 111 scientists 82–83 D-Index: 110 scientists 84–85 D-Index: 110 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 102 scientists 90–91 D-Index: 66 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 70 scientists 96–97 D-Index: 54 scientists 98–99 D-Index: 60 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 55 scientists 104–105 D-Index: 45 scientists 106–107 D-Index: 42 scientists 108–109 D-Index: 28 scientists 110–111 D-Index: 39 scientists 112–113 D-Index: 25 scientists 114–115 D-Index: 31 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 34 scientists 120–121 D-Index: 29 scientists 122–123 D-Index: 29 scientists 124–125 D-Index: 18 scientists 126–127 D-Index: 27 scientists 128–129 D-Index: 22 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 11 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 12 scientists 138–139 D-Index: 21 scientists 140–141 D-Index: 4 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 14 scientists 146–147 D-Index: 6 scientists 148–149 D-Index: 10 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 9 scientists 154–155 D-Index: 8 scientists 156–157 D-Index: 8 scientists 158–159 D-Index: 9 scientists 160+ D-Index: 96 scientists
40 D-Index 160+

This scientist: 76 D-Index — 59th percentile

59% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 160 D-Index or more.

Overview

David A. Largaespada is affiliated with the University of Minnesota in the United States. Their research activity spans fields related to Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Neurology, Oncology, Pulmonary and Respiratory Medicine, and Genetics as key subfields.

Their recent research contributions include a range of publications spanning experimental and clinical studies. Among these are:

  • APOBEC3A catalyzes mutation and drives carcinogenesis in vivo (2020, The Journal of Experimental Medicine)
  • Epigenomic, genomic, and transcriptomic landscape of schwannomatosis (2020, Acta Neuropathologica)
  • ZBTB20 regulates WNT/CTNNB1 signalling pathway by suppressing PPARG during hepatocellular carcinoma tumourigenesis (2020, JHEP Reports)
  • New Model Systems and the Development of Targeted Therapies for the Treatment of Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors (2020, Genes)
  • Cdkn2a Loss in a Model of Neurofibroma Demonstrates Stepwise Tumor Progression to Atypical Neurofibroma and MPNST (2020, Cancer Research)

David A. Largaespada's work has been published consistently in several frequent venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuro-Oncology
  • Cancer Research
  • International Journal of Molecular Sciences
  • Journal of Investigative Dermatology

The scientist collaborates regularly with several coauthors, including:

  • Kyle Williams
  • Alex T. Larsson
  • Branden S. Moriarity
  • Christopher L. Moertel
  • Tyler Jubenville

Their main topics of work involve investigations into:

  • Neurofibromatosis and Schwannoma Cases
  • Sarcoma Diagnosis and Treatment
  • Neuroblastoma Research and Treatments
  • CRISPR and Genetic Engineering
  • CAR-T cell therapy research
  • Glioma Diagnosis and Treatment
  • Protein Degradation and Inhibitors

David A. Largaespada's research outputs reflect contributions to the understanding and development of treatments for neurological cancers and genetic disorders, supported by ongoing collaborations and publications in medical and molecular biology domains. Their expertise spans both fundamental molecular mechanisms as well as clinical oncology topics.

Best Publications

  • Pluripotency of mesenchymal stem cells derived from adult marrow

    Yuehua Jiang;Balkrishna N. Jahagirdar;R. Lee Reinhardt;Robert E. Schwartz

  • Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

    Andrew V. Biankin;Andrew V. Biankin;Andrew V. Biankin;Nicola Waddell;Karin S. Kassahn;Marie Claude Gingras

  • Exome sequencing identifies frequent mutation of the SWI/SNF Complex Gene PBRM1 in renal carcinoma

    Ignacio Varela;Patrick Tarpey;Keiran Raine;Dachuan Huang

  • Recurrent R-spondin fusions in colon cancer

    Somasekar Seshagiri;Eric W. Stawiski;Steffen Durinck;Zora Modrusan

  • Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice

    David J. Rawlings;Douglas C. Saffran;Satoshi Tsukada;David A. Largaespada

  • Lymphotactin: a cytokine that represents a new class of chemokine

    Gregory S. Kelner;Jacqueline Kennedy;Kevin B. Bacon;Sarah Kleyensteuber

  • PVT1 dependence in cancer with MYC copy-number increase

    Yuen Yi Tseng;Branden S. Moriarity;Wuming Gong;Ryutaro Akiyama

  • Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia

    Takuro Nakamura;David A. Largaespada;Maxwell P. Lee;Laura A. Johnson

  • Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system

    Adam J. Dupuy;Keiko Akagi;David A. Largaespada;Neal G. Copeland

  • Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

    Partow Kebriaei;Harjeet Singh;M. Helen Huls;Matthew J. Figliola

  • Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor.

    Linda S. Park;Unja Martin;Kirsten Garka;Brian Gliniak

  • Clonal selection drives genetic divergence of metastatic medulloblastoma

    Xiaochong Wu;Paul A. Northcott;Adrian Dubuc;Adam J. Dupuy

  • Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse

    Lara S. Collier;Corey M. Carlson;Shruthi Ravimohan;Shruthi Ravimohan;Adam J. Dupuy;Adam J. Dupuy

  • Gene Transfer into Genomes of Human Cells by the Sleeping Beauty Transposon System

    Aron M Geurts;Ying Yang;Karl J Clark;Geyi Liu

  • A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer

    Timothy K. Starr;Raha Allaei;Kevin A. T. Silverstein;Rodney A. Staggs

  • Divergent clonal selection dominates medulloblastoma at recurrence

    A. Sorana Morrissy;Livia Garzia;David J.H. Shih;Scott Zuyderduyn

  • Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

    Takuro Nakamura;David A. Largaespada;John D. Shaughnessy;Nancy A. Jenkins

  • Harnessing a high cargo-capacity transposon for genetic applications in vertebrates.

    Darius Balciunas;Kirk J Wangensteen;Andrew Wilber;Jason Bell

  • Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia.

    David A. Largaespada;Camilynn I. Brannan;Nancy A. Jenkins;Neal G. Copeland

  • Erratum: Pluripotency of mesenchymal stem cells derived from adult marrow (Nature (2002) 418 (41-49) DOI: 10.1038/nature00870)

    Yuehua Jiang;Balkrishna N. Jahagirdar;R. Lee Reinhardt;Robert E. Schwartz

Frequent Co-Authors

Neal G. Copeland
Neal G. Copeland The University of Texas MD Anderson Cancer Center
Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center
Perry B. Hackett
Perry B. Hackett University of Minnesota
Nancy Ratner
Nancy Ratner Cincinnati Children's Hospital Medical Center
R. Scott McIvor
R. Scott McIvor University of Minnesota
Kevin Shannon
Kevin Shannon University of California, San Francisco
Aron M. Geurts
Aron M. Geurts Medical College of Wisconsin
David J. Adams
David J. Adams Wellcome Sanger Institute
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Andrew V. Biankin
Andrew V. Biankin University of Glasgow

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