Her primary scientific interests are in Schwann cell, Cell biology, Neurofibromatosis, Neurofibromin 1 and Neurofibroma. The study incorporates disciplines such as Cancer research, Cell signaling, Axon, Neuroscience and Neuregulin in addition to Schwann cell. Her research in Cell biology intersects with topics in Cell, Cell type and Cell growth.
The various areas that Nancy Ratner examines in her Neurofibromatosis study include Internal medicine, Endocrinology, Neuroglia and Neural crest. Her studies deal with areas such as Cell culture, Carcinogenesis, Molecular biology, Genetically modified mouse and Hyperplasia as well as Neurofibromin 1. Her Neurofibroma research integrates issues from Tumor suppressor gene, Angiogenesis and Growth factor receptor.
Her main research concerns Cancer research, Cell biology, Neurofibromatosis, Schwann cell and Neurofibroma. Her Cancer research study combines topics from a wide range of disciplines, such as Cell culture, Carcinogenesis, Immunology, Signal transduction and Malignant peripheral nerve sheath tumor. Her study on Cell biology also encompasses disciplines like
Her work deals with themes such as Internal medicine and MEK inhibitor, which intersect with Neurofibromatosis. The Schwann cell study combines topics in areas such as Cell, Axon, Neuroglia and Neuron. The concepts of her Neurofibroma study are interwoven with issues in Cancer, Epidermal growth factor receptor and Cell growth.
Cancer research, Neurofibroma, Plexiform neurofibroma, Neurofibromatosis and Cell biology are her primary areas of study. Her study in Cancer research is interdisciplinary in nature, drawing from both Cell growth, Carcinogenesis, Schwann cell, Neurofibromin 1 and Signal transduction. As a part of the same scientific family, she mostly works in the field of Neurofibroma, focusing on Chemokine and, on occasion, Macrophage and Macrophage proliferation.
Nancy Ratner has researched Plexiform neurofibroma in several fields, including Tumor suppressor gene, Internal medicine and MEK inhibitor. Her study with Neurofibromatosis involves better knowledge in Pathology. Nancy Ratner combines Cell biology and Arrestin in her research.
Nancy Ratner mostly deals with Cancer research, Plexiform neurofibroma, Internal medicine, Schwann cell and Neurofibroma. Her Cancer research research is multidisciplinary, incorporating perspectives in Cell growth, Notch proteins, Carcinogenesis, Neurofibromin 1 and Gamma secretase. Her Neurofibromin 1 study deals with Kinase intersecting with Neurofibromatosis.
In her research, Transplantation, Cell cycle, Receptor tyrosine kinase, Tyrosine kinase and Endocrinology is intimately related to Growth factor receptor, which falls under the overarching field of Schwann cell. Her Neurofibroma study incorporates themes from Chemokine and Macrophage. Her Signal transduction study is concerned with Cell biology in general.
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Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues.
Camilynn I. Brannan;Archibald S. Perkins;Kristine S. Vogel;Nancy Ratner.
Genes & Development (1994)
Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis
Jeffrey E. DeClue;Alex G. Papageorge;Jonathan A. Fletcher;Scott R. Diehl.
Cell (1992)
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility
Gerardo Morfini;Gerardo Morfini;Györgyi Szebenyi;Ravindhra Elluru;Ravindhra Elluru;Nancy Ratner;Nancy Ratner.
The EMBO Journal (2002)
The Nf2 Tumor Suppressor, Merlin, Functions in Rac-Dependent Signaling
Reuben J. Shaw;J.Guillermo Paez;Marcello Curto;Ann Yaktine.
Developmental Cell (2001)
The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes
Maryellen M. Daston;Heidi Scrable;Michael Nordlund;Anne K. Sturbaum.
Neuron (1992)
Activity of Selumetinib in Neurofibromatosis Type 1–Related Plexiform Neurofibromas
Eva Dombi;Andrea Baldwin;Leigh J. Marcus;Leigh J. Marcus;Michael J. Fisher.
The New England Journal of Medicine (2016)
Cognitive function and academic performance in neurofibromatosis 1 : Consensus statement from the NF1 Cognitive Disorders Task Force
K. N. North;V. Riccardi;C. Samango-Sprouse;R. Ferner.
Neurology (1997)
MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors
Walter J. Jessen;Shyra J. Miller;Edwin Jousma;Jianqiang Wu.
Journal of Clinical Investigation (2013)
A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor
Nancy Ratner;Shyra J. Miller.
Nature Reviews Cancer (2015)
Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/– mast cells
Feng Chun Yang;David A. Ingram;Shi Chen;Cynthia M. Hingtgen.
Journal of Clinical Investigation (2003)
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