World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
17277
World Ranking
5686
National Ranking
2695

Overview

Nancy Ratner is affiliated with Cincinnati Children's Hospital Medical Center in the United States. Their research primarily focuses on the field of Medicine, with a strong emphasis on Neurology, alongside significant contributions to Cell Biology, Cellular and Molecular Neuroscience, Molecular Biology, and Pulmonary and Respiratory Medicine.

The main topics covered in their work include:

  • Neurofibromatosis and Schwannoma Cases
  • Neuroblastoma Research and Treatments
  • Sarcoma Diagnosis and Treatment
  • Nerve injury and regeneration
  • Meningioma and schwannoma management
  • Hippo pathway signaling and YAP/TAZ
  • Glioma Diagnosis and Treatment

Nancy Ratner has authored a wide range of articles, with the following notable recent papers:

  • NF106: A Neurofibromatosis Clinical Trials Consortium Phase II Trial of the MEK Inhibitor Mirdametinib (PD-0325901) in Adolescents and Adults With NF1-Related Plexiform Neurofibromas, 2021, Journal of Clinical Oncology
  • Multiple Nf1 Schwann cell populations reprogram the plexiform neurofibroma tumor microenvironment, 2022, JCI Insight
  • HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis, 2020, Journal of Clinical Investigation
  • Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis, 2020, Cell Reports
  • Cdc42 activity in Sertoli cells is essential for maintenance of spermatogenesis, 2021, Cell Reports

The venues where Nancy Ratner frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Oncogene
  • UNC Libraries
  • JCI Insight
  • Cell Reports

The scientist collaborates regularly with a number of coauthors, including:

  • Tilat A. Rizvi
  • Jianqiang Wu
  • Kwangmin Choi
  • David A. Largaespada
  • Eva Dombi

Best Publications

  • Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues.

    Camilynn I. Brannan;Archibald S. Perkins;Kristine S. Vogel;Nancy Ratner

  • Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

    Jeffrey E. DeClue;Alex G. Papageorge;Jonathan A. Fletcher;Scott R. Diehl

  • Activity of Selumetinib in Neurofibromatosis Type 1–Related Plexiform Neurofibromas

    Eva Dombi;Andrea Baldwin;Leigh J. Marcus;Michael J. Fisher

  • Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

    Gerardo Morfini;Gerardo Morfini;Györgyi Szebenyi;Ravindhra Elluru;Ravindhra Elluru;Nancy Ratner;Nancy Ratner

  • A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor

    Nancy Ratner;Shyra J. Miller

  • The Nf2 Tumor Suppressor, Merlin, Functions in Rac-Dependent Signaling

    Reuben J. Shaw;J.Guillermo Paez;Marcello Curto;Ann Yaktine

  • The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes

    Maryellen M. Daston;Heidi Scrable;Michael Nordlund;Anne K. Sturbaum

  • MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors

    Walter J. Jessen;Shyra J. Miller;Edwin Jousma;Jianqiang Wu

  • Cognitive function and academic performance in neurofibromatosis 1 : Consensus statement from the NF1 Cognitive Disorders Task Force

    K. N. North;V. Riccardi;C. Samango-Sprouse;R. Ferner

  • Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/– mast cells

    Feng Chun Yang;David A. Ingram;Shi Chen;Cynthia M. Hingtgen

  • Mechanisms and Roles of Axon-Schwann Cell Interactions

    Gabriel Corfas;Miguel Omar Velardez;Chien Ping Ko;Nancy Ratner

  • Plexiform and Dermal Neurofibromas and Pigmentation Are Caused by Nf1 Loss in Desert Hedgehog-Expressing Cells

    Jianqiang Wu;Jon P. Williams;Tilat A. Rizvi;Jennifer J. Kordich

  • Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues

    Shyra J. Miller;Fatima Rangwala;Jon Williams;Peter Ackerman

  • Epidermal growth factor receptor expression in neurofibromatosis type 1–related tumors and NF1 animal models

    Jeffrey E. DeClue;Sue Heffelfinger;Giovanna Benvenuto;Bo Ling

  • Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells

    Patricia D. Pelton;Larry S. Sherman;Tilat A. Rizvi;Mark A. Marchionni

  • A neuronal cell surface heparan sulfate proteoglycan is required for dorsal root ganglion neuron stimulation of Schwann cell proliferation.

    N Ratner;R P Bunge;L Glaser

  • S100 is present in developing chicken neurons and Schwann cells and promotes motor neuron survival in vivo.

    Anita Bhattacharyya;Ronald W. Oppenheim;David Prevette;Blake W. Moore

  • Schwann cells from neurofibromin deficient mice exhibit activation of p21ras, inhibition of cell proliferation and morphological changes.

    Kim Ha;Rosenbaum T;Marchionni Ma;Ratner N

  • Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria.

    Scott Randall Plotkin;Jaishri O. Blakeley;D. Gareth Evans;C. Oliver Hanemann

  • Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis

    Eric P Rahrmann;Adrienne L Watson;Vincent W Keng;Kwangmin Choi

Frequent Co-Authors

Jose A. Cancelas
Jose A. Cancelas Cincinnati Children's Hospital Medical Center
David A. Largaespada
David A. Largaespada University of Minnesota
Margaret H. Collins
Margaret H. Collins Cincinnati Children's Hospital Medical Center
Margaret R. Wallace
Margaret R. Wallace University of Florida
Yi Zheng
Yi Zheng Cincinnati Children's Hospital Medical Center
Marco Giovannini
Marco Giovannini University of California, Los Angeles
David H. Gutmann
David H. Gutmann Washington University in St. Louis
Kathryn N. North
Kathryn N. North University of Melbourne
Hartmut Geiger
Hartmut Geiger University of Ulm
Bruce J. Aronow
Bruce J. Aronow Cincinnati Children's Hospital Medical Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you're considering a future in biology or biochemistry, a range of online programs and career options are available. Online biology degrees offer flexibility and a strong foundation for students who wish to pursue research, healthcare, or even education sectors. Accelerated options are also available for students who want to earn their degree faster. Online biology degrees are increasingly popular and can often be completed from anywhere in the world.

Graduates interested in nutrition might explore dietetic masters programs, which are crucial for those aiming to become registered dietitians or nutritionists. For those wanting to enter the healthcare field quickly, medical assisting serves as a valuable entry point. Programs offering financial aid for medical assistant programs make training more affordable and accessible.

As your career progresses, you could consider advancing your qualifications with specialized options such as cma to lpn bridge programs online. These bridge programs allow certified medical assistants to become licensed practical nurses, opening further opportunities in patient care and beyond.

Best Scientists Citing Nancy Ratner

Trending Scientists