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Jeroen A. A. Demmers

Jeroen A. A. Demmers

D-Index & Metrics

Molecular Biology

D-Index
75
Citations
20924
World Ranking
1189
National Ranking
31

Overview

Jeroen A. A. Demmers is affiliated with Erasmus MC in the Netherlands and has contributed extensively to the fields of biochemistry, genetics, and molecular biology. Their research portfolio spans a broad range of topics, with significant work in molecular biology, genetics, and cell biology, as well as immunology and oncology.

Demmers' research interests include various specialized topics, such as:

  • Ubiquitin and proteasome pathways
  • DNA repair mechanisms
  • Genomics and chromatin dynamics
  • RNA research and splicing
  • CRISPR and genetic engineering
  • Genetics and neurodevelopmental disorders
  • Advanced proteomics techniques and applications

Their publication record features work published in multiple venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Cell Biology
  • Science Advances
  • Nucleic Acids Research
  • Nature Communications

Notable research papers by Demmers include:

  • "An organoid-derived bronchioalveolar model for SARS-CoV-2 infection of human alveolar type II-like cells," 2020, The EMBO Journal
  • "Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability," 2021, Nature Cell Biology
  • "Dominant-acting CSF1R variants cause microglial depletion and altered astrocytic phenotype in zebrafish and adult-onset leukodystrophy," 2022, Acta Neuropathologica
  • "Dynamic de novo heterochromatin assembly and disassembly at replication forks ensures fork stability," 2023, Nature Cell Biology
  • "Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2," 2021, EMBO Reports

The scientist has collaborated frequently with several co-authors, including:

  • Karel Bezstarosti (32 co-authored publications)
  • Dick H. W. Dekkers (31 co-authored publications)
  • Wouter Doff (15 co-authored publications)
  • Wilfred F. J. van IJcken (13 co-authored publications)
  • Wim Vermeulen (12 co-authored publications)

Best Publications

  • Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

    V. Stalin Raj;Huihui Mou;Saskia L. Smits;Dick H. W. Dekkers

  • Dynamic Microtubules Regulate Dendritic Spine Morphology and Synaptic Plasticity

    Jacek Jaworski;Lukas C. Kapitein;Susana Montenegro Gouveia;Bjorn R. Dortland

  • RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3

    Lígia Tavares;Emilia Dimitrova;David Oxley;Judith Webster

  • An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells

    Debbie L.C. van den Berg;Tim Snoek;Nick P. Mullin;Adam Yates

  • Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells

    Vedashree Ramakrishnaiah;Christine Thumann;Isabel Fofana;Francois Habersetzer

  • Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

    Pierre-Olivier Mari;Bogdan I. Florea;Stephan P. Persengiev;Nicole S. Verkaik

  • TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites.

    Myrrhe van Spronsen;Myrrhe van Spronsen;Marina Mikhaylova;Marina Mikhaylova;Joanna Lipka;Joanna Lipka;Max A. Schlager

  • STIM1 Is a MT-Plus-End-Tracking Protein Involved in Remodeling of the ER

    Ilya Grigoriev;Susana Montenegro Gouveia;Babet van der Vaart;Jeroen Demmers

  • Rab6 Regulates Transport and Targeting of Exocytotic Carriers

    Ilya Grigoriev;Daniël Splinter;Nanda Keijzer;Phebe S. Wulf

  • Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators

    David Landeira;Stephan P A Sauer;Raymond Poot;Maria Dvorkina

  • CLASPs Attach Microtubule Plus Ends to the Cell Cortex through a Complex with LL5β

    Gideon Lansbergen;Ilya Grigoriev;Yuko Mimori-Kiyosue;Toshihisa Ohtsuka

  • Interfacial Anchor Properties of Tryptophan Residues in Transmembrane Peptides Can Dominate over Hydrophobic Matching Effects in Peptide−Lipid Interactions†

    M.R.R. de Planque;B.B. Bonev;J.A.A. Demmers;D.V. Greathouse

  • Bicaudal D2, Dynein, and Kinesin-1 Associate with Nuclear Pore Complexes and Regulate Centrosome and Nuclear Positioning during Mitotic Entry

    Daniël Splinter;Marvin E. Tanenbaum;Arne Lindqvist;Dick Jaarsma

  • Motor Neuron Disease-Associated Mutant Vesicle-Associated Membrane Protein-Associated Protein (VAP) B Recruits Wild-Type VAPs into Endoplasmic Reticulum-Derived Tubular Aggregates

    Eva Teuling;Suaad Ahmed;Elize Haasdijk;Jeroen Demmers

  • Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.

    Erik Engelen;Umut Akinci;Jan Christian Bryne;Jun Hou

  • UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

    Petra Schwertman;Anna Lagarou;Dick H W Dekkers;Anja Raams

  • dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing

    Anna Lagarou;Adone Mohd-Sarip;Yuri M. Moshkin;Gillian E. Chalkley

  • BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures

    Daniël Splinter;David S. Razafsky;Max A Schlager;Andrea Serra-Marques

  • Proteomics Analysis of Ring1B/Rnf2 Interactors Identifies a Novel Complex with the Fbxl10/Jhdm1B Histone Demethylase and the Bcl6 Interacting Corepressor

    Carmen Sánchez;Inés Sánchez;Jeroen A.A. Demmers;Patrick Rodriguez

  • The core spliceosome as target and effector of non-canonical ATM signalling

    Maria Tresini;Daniël O. Warmerdam;Petros Kolovos;Loes Snijder

Frequent Co-Authors

Casper C. Hoogenraad
Casper C. Hoogenraad Utrecht University
Frank Grosveld
Frank Grosveld Erasmus University Rotterdam
Anna Akhmanova
Anna Akhmanova Utrecht University
Sjaak Philipsen
Sjaak Philipsen Erasmus University Rotterdam
Wim Vermeulen
Wim Vermeulen Erasmus University Rotterdam
R. Jeroen Pasterkamp
R. Jeroen Pasterkamp Utrecht University
Dik C. van Gent
Dik C. van Gent Erasmus University Rotterdam
Bart L. Haagmans
Bart L. Haagmans Erasmus University Rotterdam

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