David H. Small

Overview

Best Publications

• The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth

  Elizabeth A. Milward;Roula Papadopoulos;Stephanie J. Fuller;Robert D. Moir

  668
  Citations

• Regulation of APP cleavage by α‐, β‐ and γ‐secretases

  Janelle Nunan;David H Small

  655
  Citations

• Alzheimer's disease and Abeta toxicity: from top to bottom.

  David Henry Small;Su San Mok;Joel C Bornstein

  620
  Citations

• A Heparin-binding Domain in the Amyloid Protein Precursor of Alzheimer's Disease Is Involved in the Regulation of Neurite Outgrowth

  DH Small;V Nurcombe;G Reed;H Clarris

  533
  Citations

• A novel zinc(II) binding site modulates the function of the beta A4 amyloid protein precursor of Alzheimer's disease.

  A I Bush;G Multhaup;R D Moir;T G Williamson

  410
  Citations

• Stream of consciousness

  David Small;Tom White

  396
  Citations

• Insights into the physiological function of the β‐amyloid precursor protein: beyond Alzheimer's disease

  Edgar Dawkins;David H. Small

  300
  Citations

• Revisiting the Role of Acetylcholinesterase in Alzheimer's Disease: Cross-Talk with P-tau and β-Amyloid.

  Maria-Salud García-Ayllón;David H Small;Jesus Avila;Javier Saez-Valero

  285
  Citations

• Non-classical actions of cholinesterases : role in cellular differentiation, tumorigenesis and Alzheimer's disease

  David H. Small;Samantha Michaelson;Gian Sberna

  258
  Citations

• The β-amyloid protein of Alzheimer's disease increases neuronal CRMP-2 phosphorylation by a Rho-GTP mechanism

  Steven Petratos;Qiao-Xin Li;Amee J George;Xu Hou

  234
  Citations

• Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration.

  Xu Hou;Marie Isabel Aguilar;David Henry Small

  218
  Citations

• Alzheimer's disease and the amyloid beta protein: What is the role of amyloid?

  David H. Small;Catriona A. McLean

  213
  Citations

• Correction: Corrigendum: N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin

  A. Ian Smith;Niwanthi W. Rajapakse;Oded Kleifeld;Bruno Lomonte

  190
  Citations

• The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase.

  Janelle Nunan;Mark S. Shearman;Frédéric Checler;Roberto Cappai

  185
  Citations

• Cholinergic Regulation of Neurite Outgrowth from Isolated Chick Sympathetic Neurons in Culture

  David H. Small;Gullveig Reed;Bryony Whitefield;Victor Nurcombe

  185
  Citations

• The Amyloid β‐Protein of Alzheimer's Disease Increases Acetylcholinesterase Expression by Increasing Intracellular Calcium in Embryonal Carcinoma P19 Cells

  Gian Sberna;Javier Sáez-Valero;Konrad Beyreuther;Colin L. Masters

  162
  Citations

• Proteolytic processing of Alzheimer's disease beta A4 amyloid precursor protein in human platelets.

  Qiao-Xin Li;Qiao-Xin Li;Geneviève Evin;Geneviève Evin;David H. Small;David H. Small;Gerd Multhaup

  152
  Citations

• Heparan Sulfates Mediate the Binding of Basic Fibroblast Growth Factor to a Specific Receptor on Neural Precursor Cells (

  Yardenah G. Brickman;Miriam D. Ford;David H. Small;Perry F. Bartlett

  148
  Citations

• Cholesterol is necessary both for the toxic effect of Abeta peptides on vascular smooth muscle cells and for Abeta binding to vascular smooth muscle cell membranes

  Supundi Subasinghe;Sharon Unabia;Colin J Barrow;Su San Mok

  145
  Citations

• Acetylcholinesterase Is Increased in the Brains of Transgenic Mice Expressing the C-Terminal Fragment (CT100) of the β-Amyloid Protein Precursor of Alzheimer's Disease

  Gian Sberna;Javier Sáez-Valero;Qiao-Xin Li;Christian Czech

  144
  Citations