What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Biochemistry, Amyloid precursor protein, Amyloid, Alzheimer's disease and P3 peptide.
His work carried out in the field of Biochemistry brings together such families of science as Neurotoxicity and Toxicity.
The concepts of his Amyloid precursor protein study are interwoven with issues in Molecular biology, Endocrinology, Senile plaques and Cell biology.
The Amyloid study combines topics in areas such as Cerebral cortex, Amyloid beta and APLP1.
The study incorporates disciplines such as Neurodegeneration and Pharmacology in addition to Amyloid beta.
His Alzheimer's disease research incorporates elements of Positron emission tomography, Genetically modified mouse and GSK-3.
His most cited work include:
- Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ (537 citations)
- Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ (537 citations)
- Metalloenzyme-like Activity of Alzheimer's Disease β-Amyloid Cu-DEPENDENT CATALYTIC CONVERSION OF DOPAMINE, CHOLESTEROL, AND BIOLOGICAL REDUCING AGENTS TO NEUROTOXIC H2O2 (512 citations)
What are the main themes of his work throughout his whole career to date?
Biochemistry, Amyloid precursor protein, Amyloid, Alzheimer's disease and Peptide are his primary areas of study.
In his research, Neurodegeneration is intimately related to Neurotoxicity, which falls under the overarching field of Biochemistry.
His Amyloid precursor protein study integrates concerns from other disciplines, such as Endocrinology and Cell biology.
His Amyloid research focuses on subjects like Alpha-synuclein, which are linked to Fibril, Lewy body and Oligomer.
His research integrates issues of Genetically modified mouse, Neuroscience, Pathogenesis and Binding site in his study of Alzheimer's disease.
His Peptide research incorporates themes from Cleavage, Biophysics, Peptide sequence, Stereochemistry and Histidine.
He most often published in these fields:
- Biochemistry (48.98%)
- Amyloid precursor protein (49.56%)
- Amyloid (29.74%)
What were the highlights of his more recent work (between 2010-2021)?
- Amyloid precursor protein (49.56%)
- Cell biology (18.66%)
- Neuroprotection (7.87%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Amyloid precursor protein, Cell biology, Neuroprotection, Biochemistry and Amyloid.
His Amyloid precursor protein study falls within the topics of Alzheimer's disease and Internal medicine.
His biological study spans a wide range of topics, including Viability assay, Vesicle and Mitochondrial permeability transition pore.
His research in Biochemistry intersects with topics in Biophysics and Alpha-synuclein.
Roberto Cappai focuses mostly in the field of Amyloid, narrowing it down to topics relating to APLP2 and, in certain cases, APLP1.
His work focuses on many connections between Pharmacology and other disciplines, such as Neurotoxicity, that overlap with his field of interest in Programmed cell death, Superoxide dismutase and Peptide.
Between 2010 and 2021, his most popular works were:
- Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export (345 citations)
- 18F-THK523: a novel in vivo tau imaging ligand for Alzheimer’s disease (254 citations)
- Tau-mediated iron export prevents ferroptotic damage after ischemic stroke. (158 citations)
In his most recent research, the most cited papers focused on:
Roberto Cappai mostly deals with Amyloid precursor protein, Neuroprotection, Neurotoxicity, Pharmacology and Pathology.
His Amyloid precursor protein study is related to the wider topic of Internal medicine.
Roberto Cappai interconnects Biochemistry, Peptide, Polymyxin B and Colistin in the investigation of issues within Neurotoxicity.
His studies in Biochemistry integrate themes in fields like PBT2, Biophysics and Cell biology.
Roberto Cappai has included themes like Oxidative stress, Superoxide dismutase, Antibiotics, Polymyxin and Apoptosis in his Pharmacology study.
His Alzheimer's disease study combines topics in areas such as MPTP, Genetically modified mouse, Parkinsonism and Amyloid.
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