D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 76 Citations 19,640 231 World Ranking 2149 National Ranking 158

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Organic chemistry

David R. Brown mainly focuses on Biochemistry, Cell biology, Oxidative stress, Gene isoform and Neurodegeneration. David R. Brown specializes in Biochemistry, namely Superoxide dismutase. He combines subjects such as Scrapie, Neuroglia, Virology, Astrocyte and Glycoprotein with his study of Cell biology.

His Oxidative stress research is multidisciplinary, incorporating perspectives in Oxidative phosphorylation, Gene, Antioxidant and Methionine. His biological study spans a wide range of topics, including Cell culture and Immunology, Ratón. His Neurodegeneration research integrates issues from Glutamate receptor, Protein aggregation and Mutation.

His most cited work include:

  • The cellular prion protein binds copper in vivo (1110 citations)
  • Normal prion protein has an activity like that of superoxide dismutase. (484 citations)
  • Role of microglia and host prion protein in neurotoxicity of a prion protein fragment (468 citations)

What are the main themes of his work throughout his whole career to date?

Biochemistry, Inorganic chemistry, Cell biology, Catalysis and Scrapie are his primary areas of study. His Biochemistry research includes themes of Prion protein and Copper. His study looks at the intersection of Inorganic chemistry and topics like Uranium with Crystallography.

His Cell biology study incorporates themes from Neuroglia, Glutamate receptor, Astrocyte, Toxicity and Programmed cell death. His Scrapie study combines topics in areas such as Recombinant DNA and Virology. His studies in Virology integrate themes in fields like Bovine spongiform encephalopathy and Disease, Neurodegeneration.

He most often published in these fields:

  • Biochemistry (21.74%)
  • Inorganic chemistry (16.56%)
  • Cell biology (13.87%)

What were the highlights of his more recent work (between 2011-2021)?

  • Cancer research (3.73%)
  • Cancer (3.52%)
  • Biochemistry (21.74%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cancer research, Cancer, Biochemistry, Cell biology and Catalysis. His Cancer research study also includes

  • Cancer cell, which have a strong connection to Ovarian cancer, Immunology, Neuroblastoma and Lung cancer,
  • microRNA together with Liver cancer. His work deals with themes such as Biophysics, Function and Alpha-synuclein, which intersect with Biochemistry.

His Cell biology course of study focuses on Synuclein and Neuroscience. In his research on the topic of Catalysis, Adsorption, Metal, Reactive oxygen species and Zinc is strongly related with Inorganic chemistry. His study explores the link between Protein aggregation and topics such as Mutation that cross with problems in Neurodegeneration.

Between 2011 and 2021, his most popular works were:

  • Seeking a Mechanism for the Toxicity of Oligomeric α-Synuclein (123 citations)
  • Mechanisms of catalytic ozonation: An investigation into superoxide ion radical and hydrogen peroxide formation during catalytic ozonation on alumina and zeolites in water (109 citations)
  • Mechanisms of catalytic ozonation on alumina and zeolites in water: Formation of hydroxyl radicals (104 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Organic chemistry

His scientific interests lie mostly in Biochemistry, Catalysis, Organic chemistry, Neurodegeneration and Cell biology. David R. Brown combines subjects such as Biophysics, Function, Alpha-synuclein and Amyloid with his study of Biochemistry. His Biophysics research includes elements of Protein structure, Scrapie, Alzheimer's disease and Protein folding.

His Catalysis study integrates concerns from other disciplines, such as Inorganic chemistry, Adsorption, Molecule, Sugar and Radical. His study in Neurodegeneration is interdisciplinary in nature, drawing from both Quinolinic acid and Glial cell line-derived neurotrophic factor, Neurotrophic factors. His biological study spans a wide range of topics, including Cell, Glutamate receptor, Secretion, Transfection and Wild type.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The cellular prion protein binds copper in vivo

D R Brown;K Qin;J W Herms;A Madlung.
Nature (1997)

1559 Citations

Normal prion protein has an activity like that of superoxide dismutase.

David R. Brown;Boon-Seng Wong;Farida Hafiz;Christine Clive.
Biochemical Journal (1999)

695 Citations

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment

David R. Brown;Bernhard Schmidt;Hans A. Kretzschmar.
Nature (1996)

652 Citations

Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity

David R. Brown;Walter J. Schulz-Schaeffer;Bernhard Schmidt;Hans A. Kretzschmar.
Experimental Neurology (1997)

577 Citations

Prion protein expression and superoxide dismutase activity.

David R. Brown;Andreas Besinger.
Biochemical Journal (1998)

352 Citations

Biological inorganic and bioinorganic chemistry of neurodegeneration based on prion and Alzheimer diseases.

David R. Brown;Henryk Kozlowski.
Dalton Transactions (2004)

346 Citations

Consequences of manganese replacement of copper for prion protein function and proteinase resistance

David R. Brown;Farida Hafiz;Leslie L. Glasssmith;Boon-Seng Wong.
The EMBO Journal (2000)

320 Citations

Role of Microglia in Neuronal Cell Death in Prion Disease

Armin Giese;David R. Brown;Martin H. Groschup;Claudia Feldmann.
Brain Pathology (2006)

283 Citations

Structure-activity relations in Cs-doped heteropolyacid catalysts for biodiesel production

K. Narasimharao;D.R. Brown;Adam Lee;A.D. Newman.
Journal of Catalysis (2007)

282 Citations

Preferential Cu2+ Coordination by His96 and His111 Induces β-Sheet Formation in the Unstructured Amyloidogenic Region of the Prion Protein

Christopher E. Jones;Salama R. Abdelraheim;David R. Brown;John H. Viles.
Journal of Biological Chemistry (2004)

279 Citations

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