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Biology and Biochemistry

D-Index
59
Citations
10264
World Ranking
12758
National Ranking
5440

Overview

Man Sun Sy is affiliated with Case Western Reserve University in the United States. Their research spans multiple areas within medicine and health professions, with a particular focus on dementia, geriatric care, and palliative care.

The main fields of study for Sy include Medicine and Health Professions. Within these, Sy's work touches on several subfields:

  • General Health Professions
  • Psychiatry and Mental Health
  • Public Health, Environmental and Occupational Health
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

The primary research topics addressed by Sy encompass:

  • Dementia and Cognitive Impairment Research
  • Geriatric Care and Nursing Homes
  • Palliative Care and End-of-Life Issues
  • Older Adults Driving Studies
  • Stroke Rehabilitation and Recovery
  • Frailty in Older Adults
  • Health Systems, Economic Evaluations, Quality of Life

Sy has published scientific papers in several venues, including:

  • Innovation in Aging
  • JMIR Research Protocols
  • Pilot and Feasibility Studies
  • The Journal of Frailty & Aging
  • Journal of Palliative Medicine

Among Sy's recent publications are the following papers:

  • Using a Claims-Based Frailty Index to Investigate Frailty, Survival, and Healthcare Expenditures among Older Adults Hospitalized for COVID-19 at an Academic Medical Center, 2023, The Journal of Frailty & Aging
  • Bio-Experiential Technology to Support Persons With Dementia and Care Partners at Home (TEND): Protocol for an Intervention Development Study, 2023, JMIR Research Protocols
  • Caring for caregivers and persons living with dementia under home-based primary care: protocol for an interventional clinical trial, 2024, Pilot and Feasibility Studies
  • Palliative Care Clinical Trials in Underrepresented Ethnic and Racial Minorities: A Narrative Review, 2023, Journal of Palliative Medicine
  • Stakeholder Engagement to Inform and Refine an Existing Dementia Care Model in Home-Based Primary Care: The Co-Creation of Dementia Care Quality at Home, 2025, Journal of Applied Gerontology

Sy frequently collaborates with several co-authors, including:

  • Christine S. Ritchie
  • Ana-Maria Vranceanu
  • Ayush Thacker
  • Elizabeth A Rochon
  • Mirelle Phillips

Best Publications

  • A new human prostate carcinoma cell line, 22Rv1.

    R. Michael Sramkoski;Thomas G. Pretlow;Joseph M. Giaconia;Theresa P. Pretlow

  • The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and α2–6 sialyltransferase, CD75, on B cells

    Ivan Stamenkovic;Dennis Sgroi;Alejandro Aruffo;Man Sun Sy

  • Chronic Wasting Disease of Elk: Transmissibility to Humans Examined by Transgenic Mouse Models

    Qingzhong Kong;Shenghai Huang;Wenquan Zou;Difernando Vanegas

  • A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy.

    Jean C. Manson;Elizabeth Jamieson;Herbert Baybutt;Nadia L. Tuzi

  • Expression of hyaluronidase by tumor cells induces angiogenesis in vivo

    Dacai Liu;Eric Pearlman;Eugenia Diaconu;Kun Guo

  • Aberrant metal binding by prion protein in human prion disease.

    Boon Seng Wong;Shu G. Chen;Monica Colucci;Zhiliang Xie

  • Prion protein expression in different species: Analysis with a panel of new mAbs

    Gianluigi Zanusso;Dacai Liu;Sergio Ferrari;Ivan Hegyi

  • Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein

    Boon Seng Wong;Tong Liu;Ruliang Li;Tao Pan

  • Antigen- and receptor-driven regulatory mechanisms. IV. Idiotype-bearing I-J + suppressor T cell factors induce second-order suppressor T cells which express anti-idiotypic receptors

    M S Sy;M H Dietz;R N Germain;B Benacerraf

  • Cell-surface prion protein interacts with glycosaminoglycans.

    Tao Pan;Boon Seng Wong;Tong Liu;Ruliang Li

  • Anti-prion antibodies for prophylaxis following prion exposure in mice.

    Einar M. Sigurdsson;Man Sun Sy;Ruliang Li;Henrieta Scholtzova

  • Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities.

    Boon Seng Wong;David R. Brown;Tao Pan;Matthew Whiteman

  • The CNS glycoprotein Shadoo has PrPC‐like protective properties and displays reduced levels in prion infections

    Joel C. Watts;Bettina Drisaldi;Vivian Ng;Jing Yang

  • Down-Regulation of the Transporter for Antigen Presentation, Proteasome Subunits, and Class I Major Histocompatibility Complex in Tumor Cell Lines

    Alyssa Johnsen;Man Sun Sy;Clifford V. Harding

  • Identification of Novel Proteinase K-resistant C-terminal Fragments of PrP in Creutzfeldt-Jakob Disease

    Wen Quan Zou;Sabina Capellari;Piero Parchi;Man Sun Sy

  • Cellular and subcellular morphological localization of normal prion protein in rodent cerebellum

    Jeanne Lainé;Marie Elizabeth Marc;Man Sun Sy;Herbert Axelrad

  • Clearance and prevention of prion infection in cell culture by anti-PrP antibodies

    Joanna Pankiewicz;Frances Prelli;Man Sun Sy;Richard J. Kascsak

  • Differential contribution of superoxide dismutase activity by prion protein in vivo.

    Boon Seng Wong;Tao Pan;Tong Liu;Ruliang Li

  • The expression and potential function of cellular prion protein in human lymphocytes.

    Ruliang Li;Dacai Liu;Gianluigi Zanusso;Tong Liu

  • In Vivo Treatment with Anti-ICAM-1 and Anti-LFA-1 Antibodies Inhibits Contact Sensitization-Induced Migration of Epidermal Langerhans Cells to Regional Lymph Nodes

    Jing Ma;Jin Hong Wang;Ya Jun Guo;Man Sun Sy

Frequent Co-Authors

Pierluigi Gambetti
Pierluigi Gambetti Case Western Reserve University
Tao Pan
Tao Pan Jinan University
Robert B. Petersen
Robert B. Petersen Case Western Reserve University
Po Tien
Po Tien Chinese Academy of Sciences
David R. Brown
David R. Brown University of Bath
Thomas Wisniewski
Thomas Wisniewski New York University
Ian M. Jones
Ian M. Jones University of Reading
James W. Ironside
James W. Ironside University of Edinburgh
Mark A. Smith
Mark A. Smith Case Western Reserve University
George Perry
George Perry The University of Texas at San Antonio

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