Po Tien spends much of his time researching Virology, Coronavirus, Virus, RNA and Viral entry. His Virology research is multidisciplinary, incorporating perspectives in Molecular biology, Immunology and Peptide. His research in Virus intersects with topics in ELISPOT, Natural selection and Antigenicity.
His research integrates issues of HEK 293 cells and Messenger RNA in his study of RNA. His studies deal with areas such as Lipid bilayer fusion, Viral protein and Fusion protein as well as Viral entry. Po Tien interconnects Helix bundle, Protein structure and Fusion mechanism in the investigation of issues within Fusion protein.
His primary areas of study are Virology, Virus, Molecular biology, Biochemistry and Heptad repeat. He has included themes like RNA, Immunology and Fusion protein in his Virology study. Po Tien focuses mostly in the field of Virus, narrowing it down to matters related to Cell fusion and, in some cases, Endogenous retrovirus.
Po Tien works mostly in the field of Molecular biology, limiting it down to topics relating to Recombinant DNA and, in certain cases, Mutant, as a part of the same area of interest. His work deals with themes such as Cell culture and Stereochemistry, which intersect with Biochemistry. He integrates Heptad repeat with Coronavirus in his research.
His scientific interests lie mostly in Virology, Cell biology, Stereochemistry, Virus and Viral replication. His Virology research incorporates themes from Epitope, Cytotoxic T cell and Immune system, Immunology. His Neuraminidase and Viral entry study, which is part of a larger body of work in Virus, is frequently linked to Oseltamivir and Zanamivir, bridging the gap between disciplines.
The concepts of his Viral replication study are interwoven with issues in Polymerase, Signal transducing adaptor protein, Ribonucleoprotein, Genome and Nucleoprotein. His work in Signal transducing adaptor protein tackles topics such as Cytoplasm which are related to areas like Molecular biology. His Hepatitis B virus study which covers DNA virus that intersects with Signal transduction.
Po Tien mostly deals with RNA, Virology, Gene knockdown, Molecular biology and Cell culture. He combines subjects such as Polymerase and Transcription with his study of RNA. His study in Viral entry and Virus are all subfields of Virology.
His biological study spans a wide range of topics, including Ribonuclease III, Cytochrome c, Mitochondrion and Recombinant DNA. His work on Protein biosynthesis as part of general Molecular biology study is frequently connected to Internal ribosome entry site, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His work in Cell culture covers topics such as Plasma protein binding which are related to areas like Cell.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
Bo Zhong;Yan Yang;Shu Li;Yan Yi Wang.
Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors.
Shuwen Liu;Gengfu Xiao;Yibang Chen;Yuxian He.
The Lancet (2004)
PD-1 and PD-L1 upregulation promotes CD8+ T-cell apoptosis and postoperative recurrence in hepatocellular carcinoma patients
Feng Shi;Ming Shi;Zhen Zeng;Rui-Zhao Qi.
International Journal of Cancer (2011)
Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase
Yu Chen;Hui Cai;Ji'an Pan;Nian Xiang.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex.
Yu Chen;Ceyang Su;Min Ke;Xu Jin.
PLOS Pathogens (2011)
Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core.
Yanhui Xu;Zhiyong Lou;Yiwei Liu;Hai Pang.
Journal of Biological Chemistry (2004)
Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients
Lun Cai;Zheng Zhang;Lin Zhou;Haiyan Wang.
Clinical Immunology (2008)
Identification of Novel Subgenomic RNAs and Noncanonical Transcription Initiation Signals of Severe Acute Respiratory Syndrome Coronavirus
Snawar Hussain;Ji'an Pan;Yu Chen;Yalin Yang.
Journal of Virology (2005)
Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6.
Shu Li;Hao Zheng;Ai-Ping Mao;Bo Zhong.
Journal of Biological Chemistry (2010)
Circulating microRNAs in hepatitis B virus–infected patients
F Ji;B Yang;X Peng;H Ding.
Journal of Viral Hepatitis (2011)
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