What is he best known for?
The fields of study he is best known for:
Po Tien spends much of his time researching Virology, Coronavirus, Virus, RNA and Viral entry.
His Virology research is multidisciplinary, incorporating perspectives in Molecular biology, Immunology and Peptide.
His research in Virus intersects with topics in ELISPOT, Natural selection and Antigenicity.
His research integrates issues of HEK 293 cells and Messenger RNA in his study of RNA.
His studies deal with areas such as Lipid bilayer fusion, Viral protein and Fusion protein as well as Viral entry.
Po Tien interconnects Helix bundle, Protein structure and Fusion mechanism in the investigation of issues within Fusion protein.
His most cited work include:
- The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation (876 citations)
- Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors. (340 citations)
- PD‐1 and PD‐L1 upregulation promotes CD8+ T‐cell apoptosis and postoperative recurrence in hepatocellular carcinoma patients (273 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Virology, Virus, Molecular biology, Biochemistry and Heptad repeat.
He has included themes like RNA, Immunology and Fusion protein in his Virology study.
Po Tien focuses mostly in the field of Virus, narrowing it down to matters related to Cell fusion and, in some cases, Endogenous retrovirus.
Po Tien works mostly in the field of Molecular biology, limiting it down to topics relating to Recombinant DNA and, in certain cases, Mutant, as a part of the same area of interest.
His work deals with themes such as Cell culture and Stereochemistry, which intersect with Biochemistry.
He integrates Heptad repeat with Coronavirus in his research.
He most often published in these fields:
- Virology (50.59%)
- Virus (34.12%)
- Molecular biology (28.24%)
What were the highlights of his more recent work (between 2013-2021)?
- Virology (50.59%)
- Cell biology (9.41%)
- Stereochemistry (7.06%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Virology, Cell biology, Stereochemistry, Virus and Viral replication.
His Virology research incorporates themes from Epitope, Cytotoxic T cell and Immune system, Immunology.
His Neuraminidase and Viral entry study, which is part of a larger body of work in Virus, is frequently linked to Oseltamivir and Zanamivir, bridging the gap between disciplines.
The concepts of his Viral replication study are interwoven with issues in Polymerase, Signal transducing adaptor protein, Ribonucleoprotein, Genome and Nucleoprotein.
His work in Signal transducing adaptor protein tackles topics such as Cytoplasm which are related to areas like Molecular biology.
His Hepatitis B virus study which covers DNA virus that intersects with Signal transduction.
Between 2013 and 2021, his most popular works were:
- Cell Surface Vimentin is an Attachment Receptor for Enterovirus 71 (94 citations)
- The Nucleocapsid Protein of Coronaviruses Acts as a Viral Suppressor of RNA Silencing in Mammalian Cells (87 citations)
- Enterovirus 71 2B Induces Cell Apoptosis by Directly Inducing the Conformational Activation of the Proapoptotic Protein Bax. (31 citations)
In his most recent research, the most cited papers focused on:
Po Tien mostly deals with RNA, Virology, Gene knockdown, Molecular biology and Cell culture.
He combines subjects such as Polymerase and Transcription with his study of RNA.
His study in Viral entry and Virus are all subfields of Virology.
His biological study spans a wide range of topics, including Ribonuclease III, Cytochrome c, Mitochondrion and Recombinant DNA.
His work on Protein biosynthesis as part of general Molecular biology study is frequently connected to Internal ribosome entry site, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His work in Cell culture covers topics such as Plasma protein binding which are related to areas like Cell.
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