D-Index & Metrics Best Publications
Biology and Biochemistry
China
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 75 Citations 33,874 192 World Ranking 3250 National Ranking 67

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in China Leader Award

2012 - Fellow, The World Academy of Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Apoptosis

His primary areas of investigation include Cell biology, Cancer research, Signal transduction, Molecular biology and Transcription factor. His Cell biology research incorporates themes from TRIF, TNF Receptor-Associated Factor 3, Receptor, Peptide sequence and Death domain. His studies in Cancer research integrate themes in fields like TRADD, NF-κB, FADD, Caspase 8 and TRAF3.

His work carried out in the field of Signal transduction brings together such families of science as Interferon, Kinase and Tumor Necrosis Factor Receptor-Associated Factors. His study in Transcription factor is interdisciplinary in nature, drawing from both Protein subunit, Gene expression, Signal transducing adaptor protein and Virology. His biological study spans a wide range of topics, including CARD domain, RIG-I, RIG-I-like receptor and MDA5.

His most cited work include:

  • TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways (1811 citations)
  • VISA Is an Adapter Protein Required for Virus-Triggered IFN-β Signaling (1521 citations)
  • VISA Is an Adapter Protein Required for Virus-Triggered IFN-β Signaling (1521 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cell biology, Signal transduction, Molecular biology, Transcription factor and Innate immune system. His Cell biology research is multidisciplinary, relying on both Receptor and Ubiquitin, Ubiquitin ligase. His Signal transduction study combines topics in areas such as Interferon, Virology, Cancer research and TRIF.

The study incorporates disciplines such as RIG-I and MDA5 in addition to Virology. As a member of one scientific family, Hong-Bing Shu mostly works in the field of Molecular biology, focusing on Tumor necrosis factor alpha and, on occasion, Protein kinase A and Zinc finger. His work investigates the relationship between Transcription factor and topics such as Gene knockdown that intersect with problems in RNA interference.

He most often published in these fields:

  • Cell biology (66.35%)
  • Signal transduction (33.17%)
  • Molecular biology (43.27%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (66.35%)
  • Innate immune system (26.44%)
  • DNA (6.25%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Innate immune system, DNA, Immune system and Signal transducing adaptor protein. Hong-Bing Shu studies Cell biology, focusing on Signal transduction in particular. His Innate immune system research is multidisciplinary, incorporating elements of Regulator, Gene and Phosphatase, Phosphorylation.

His Immune system research includes themes of Protein kinase A, ATP synthase and Pathogenesis. His research investigates the connection between Signal transducing adaptor protein and topics such as Deubiquitination that intersect with problems in Plasma protein binding, HEK 293 cells and Kinase. He has included themes like TRIF and Zinc finger in his TLR3 study.

Between 2017 and 2021, his most popular works were:

  • The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors. (44 citations)
  • ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response (42 citations)
  • Cytoplasmic Mechanisms of Recognition and Defense of Microbial Nucleic Acids. (35 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Apoptosis

Cell biology, Innate immune system, IRF3, Signal transducing adaptor protein and DNA are his primary areas of study. His Cell biology research incorporates elements of RNA, RIG-I, RNA virus, Ubiquitin and Immune system. The concepts of his Innate immune system study are interwoven with issues in Cytoplasm, Signal transduction, Second messenger system, Phosphorylation and SUMO protein.

His Signal transducing adaptor protein study incorporates themes from Transcription and Deubiquitination. He combines subjects such as Ubiquitin ligase, TLR3, TRIF and TLR4 with his study of Deubiquitination. The various areas that Hong-Bing Shu examines in his Gene knockdown study include Autophagy, Interferon and Transcription factor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways

Hailing Hsu;Hong Bing Shu;Ming Gui Pan;David V. Goeddel.
Cell (1996)

2539 Citations

VISA Is an Adapter Protein Required for Virus-Triggered IFN-β Signaling

Liang-Guo Xu;Yan-Yi Wang;Ke-Jun Han;Lian-Yun Li.
Molecular Cell (2005)

1943 Citations

TNF-dependent Recruitment of the Protein Kinase RIP to the TNF receptor-1 Signaling Complex

Hailing Hsu;Jianing Huang;Hong-Bing Shu;Vijay Baichwal.
Immunity (1996)

1480 Citations

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

Bo Zhong;Yan Yang;Shu Li;Yan Yi Wang.
Immunity (2008)

1285 Citations

FADD: Essential for Embryo Development and Signaling from Some, But Not All, Inducers of Apoptosis

Wen-Chen Yeh;José Luis de la Pompa;Mila E. McCurrach;Hong-Bing Shu.
Science (1998)

1155 Citations

Requirement for Casper (c-FLIP) in Regulation of Death Receptor–Induced Apoptosis and Embryonic Development

Wen-Chen Yeh;Annick Itie;Andrew J Elia;Michelle Ng.
Immunity (2000)

602 Citations

Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.

Robin Lesley;Ying Xu;Susan L Kalled;Donna M Hess.
Immunity (2004)

588 Citations

Casper is a FADD- and caspase-related inducer of apoptosis.

Hong-Bing Shu;David R Halpin;David V Goeddel.
Immunity (1997)

518 Citations

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

Hong Bing Shu;Masahiro Takeuchi;David V. Goeddel.
Proceedings of the National Academy of Sciences of the United States of America (1996)

503 Citations

TALL‐1 is a novel member of the TNF family that is down‐regulated by mitogens

Hong-Bing Shu;Wen-Hui Hu;Holly Johnson.
Journal of Leukocyte Biology (1999)

502 Citations

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