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Hong-Bing Shu

Hong-Bing Shu

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Biology and Biochemistry
China
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
89
Citations
41675
World Ranking
2505
National Ranking
58

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in China Leader Award
  • 2012 - Fellow, The World Academy of Sciences

Overview

Hong-Bing Shu is a researcher affiliated with Wuhan University in China, specializing in immunology and microbiology. Their academic contributions are distributed primarily across the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. More specifically, their work encompasses subfields such as Immunology, Molecular Biology, Oncology, Infectious Diseases, and Epidemiology.

The research topics addressed by Hong-Bing Shu include:

  • Interferon and immune responses
  • Immune cell function and interaction
  • Immune response and inflammation
  • Viral infections and vectors
  • RNA regulation and disease
  • Cytokine signaling pathways and interactions
  • NF-κB signaling pathways

They have an extensive record of publications, with a notable presence in several scientific journals. The most frequent publication venues include:

  • Cellular and Molecular Immunology
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • Journal of Molecular Cell Biology
  • Cell Discovery

Recent papers authored or co-authored by Hong-Bing Shu span investigations into innate immunity, tumor microenvironments, and cellular metabolism in immune function. Some of these publications are:

  • "USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy," 2022, Nature Communications
  • "DNA-PK deficiency potentiates cGAS-mediated antiviral innate immunity," 2020, Nature Communications
  • "Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis," 2020, Cell Discovery
  • "Mitochondrial DNA-triggered innate immune response: mechanisms and diseases," 2023, Cellular and Molecular Immunology
  • "STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2," 2023, Nature Cell Biology

Hong-Bing Shu frequently collaborates with other researchers. Notable frequent co-authors include Shu Li, Ming-Ming Hu, Li-Bo Cao, Zi-Lun Ruan, and Li Zhong.

Their contributions have been recognized with distinctions such as the fellowship of The World Academy of Sciences, awarded in 2012.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways

    Hailing Hsu;Hong Bing Shu;Ming Gui Pan;David V. Goeddel

  • VISA Is an Adapter Protein Required for Virus-Triggered IFN-β Signaling

    Liang-Guo Xu;Yan-Yi Wang;Ke-Jun Han;Lian-Yun Li

  • The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

    Bo Zhong;Yan Yang;Shu Li;Yan Yi Wang

  • TNF-dependent Recruitment of the Protein Kinase RIP to the TNF receptor-1 Signaling Complex

    Hailing Hsu;Jianing Huang;Hong-Bing Shu;Vijay Baichwal

  • FADD: Essential for Embryo Development and Signaling from Some, But Not All, Inducers of Apoptosis

    Wen-Chen Yeh;José Luis de la Pompa;Mila E. McCurrach;Hong-Bing Shu

  • Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.

    Robin Lesley;Ying Xu;Susan L Kalled;Donna M Hess

  • Requirement for Casper (c-FLIP) in Regulation of Death Receptor–Induced Apoptosis and Embryonic Development

    Wen-Chen Yeh;Annick Itie;Andrew J Elia;Michelle Ng

  • The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

    Hong Bing Shu;Masahiro Takeuchi;David V. Goeddel

  • Casper is a FADD- and caspase-related inducer of apoptosis.

    Hong-Bing Shu;David R Halpin;David V Goeddel

  • TALL‐1 is a novel member of the TNF family that is down‐regulated by mitogens

    Hong-Bing Shu;Wen-Hui Hu;Holly Johnson

  • Direct transfer of transforming growth factor beta 1 gene into arteries stimulates fibrocellular hyperplasia

    E G Nabel;L Shum;V J Pompili;Z Y Yang

  • The Ubiquitin Ligase RNF5 Regulates Antiviral Responses by Mediating Degradation of the Adaptor Protein MITA

    Bo Zhong;Lu Zhang;Caoqi Lei;Ying Li

  • TRIM32 Protein Modulates Type I Interferon Induction and Cellular Antiviral Response by Targeting MITA/STING Protein for K63-linked Ubiquitination

    Jing Zhang;Ming-Ming Hu;Yan-Yi Wang;Hong-Bing Shu

  • Activation of NF-κB by FADD, Casper, and Caspase-8

    Wen-Hui Hu;Holly Johnson;Hong-Bing Shu;Hong-Bing Shu

  • Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus

    Ming-Ming Hu;Qing Yang;Xue-Qin Xie;Chen-Yang Liao

  • Mechanisms of the TRIF-induced Interferon-stimulated Response Element and NF-κB Activation and Apoptosis Pathways

    Ke-Jun Han;Xiaoqin Su;Liang-Guo Xu;Liang-Hua Bin

  • Tumor Necrosis Factor-related Apoptosis-inducing Ligand Receptors Signal NF-κB and JNK Activation and Apoptosis through Distinct Pathways

    Wen-Hui Hu;Holly Johnson;Hong-Bing Shu

  • NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING

    Lu Zhang;Jinyao Mo;Karen V. Swanson;Haitao Wen

  • AMID, an Apoptosis-inducing Factor-homologous Mitochondrion-associated Protein, Induces Caspase-independent Apoptosis

    Min Wu;Liang-Guo Xu;Xiaoyan Li;Zhonghe Zhai

Frequent Co-Authors

David V. Goeddel
David V. Goeddel The Colum Group
Po Tien
Po Tien Chinese Academy of Sciences
John W. Kappler
John W. Kappler National Jewish Health
Deyin Guo
Deyin Guo Sun Yat-sen University
Yong-Jun Liu
Yong-Jun Liu University of Washington
Elizabeth G. Nabel
Elizabeth G. Nabel Brigham and Women's Hospital
Andrew J. Elia
Andrew J. Elia Princess Margaret Cancer Centre
Andrew Wakeham
Andrew Wakeham Princess Margaret Cancer Centre
Zhigao Bu
Zhigao Bu Harbin Veterinary Research Institute
Xian-Zheng Zhang
Xian-Zheng Zhang Wuhan University

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