2023 - Research.com Biology and Biochemistry in China Leader Award
2012 - Fellow, The World Academy of Sciences
His primary areas of investigation include Cell biology, Cancer research, Signal transduction, Molecular biology and Transcription factor. His Cell biology research incorporates themes from TRIF, TNF Receptor-Associated Factor 3, Receptor, Peptide sequence and Death domain. His studies in Cancer research integrate themes in fields like TRADD, NF-κB, FADD, Caspase 8 and TRAF3.
His work carried out in the field of Signal transduction brings together such families of science as Interferon, Kinase and Tumor Necrosis Factor Receptor-Associated Factors. His study in Transcription factor is interdisciplinary in nature, drawing from both Protein subunit, Gene expression, Signal transducing adaptor protein and Virology. His biological study spans a wide range of topics, including CARD domain, RIG-I, RIG-I-like receptor and MDA5.
His main research concerns Cell biology, Signal transduction, Molecular biology, Transcription factor and Innate immune system. His Cell biology research is multidisciplinary, relying on both Receptor and Ubiquitin, Ubiquitin ligase. His Signal transduction study combines topics in areas such as Interferon, Virology, Cancer research and TRIF.
The study incorporates disciplines such as RIG-I and MDA5 in addition to Virology. As a member of one scientific family, Hong-Bing Shu mostly works in the field of Molecular biology, focusing on Tumor necrosis factor alpha and, on occasion, Protein kinase A and Zinc finger. His work investigates the relationship between Transcription factor and topics such as Gene knockdown that intersect with problems in RNA interference.
His scientific interests lie mostly in Cell biology, Innate immune system, DNA, Immune system and Signal transducing adaptor protein. Hong-Bing Shu studies Cell biology, focusing on Signal transduction in particular. His Innate immune system research is multidisciplinary, incorporating elements of Regulator, Gene and Phosphatase, Phosphorylation.
His Immune system research includes themes of Protein kinase A, ATP synthase and Pathogenesis. His research investigates the connection between Signal transducing adaptor protein and topics such as Deubiquitination that intersect with problems in Plasma protein binding, HEK 293 cells and Kinase. He has included themes like TRIF and Zinc finger in his TLR3 study.
Cell biology, Innate immune system, IRF3, Signal transducing adaptor protein and DNA are his primary areas of study. His Cell biology research incorporates elements of RNA, RIG-I, RNA virus, Ubiquitin and Immune system. The concepts of his Innate immune system study are interwoven with issues in Cytoplasm, Signal transduction, Second messenger system, Phosphorylation and SUMO protein.
His Signal transducing adaptor protein study incorporates themes from Transcription and Deubiquitination. He combines subjects such as Ubiquitin ligase, TLR3, TRIF and TLR4 with his study of Deubiquitination. The various areas that Hong-Bing Shu examines in his Gene knockdown study include Autophagy, Interferon and Transcription factor.
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TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways
Hailing Hsu;Hong Bing Shu;Ming Gui Pan;David V. Goeddel.
Cell (1996)
VISA Is an Adapter Protein Required for Virus-Triggered IFN-β Signaling
Liang-Guo Xu;Yan-Yi Wang;Ke-Jun Han;Lian-Yun Li.
Molecular Cell (2005)
TNF-dependent Recruitment of the Protein Kinase RIP to the TNF receptor-1 Signaling Complex
Hailing Hsu;Jianing Huang;Hong-Bing Shu;Vijay Baichwal.
Immunity (1996)
The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
Bo Zhong;Yan Yang;Shu Li;Yan Yi Wang.
Immunity (2008)
FADD: Essential for Embryo Development and Signaling from Some, But Not All, Inducers of Apoptosis
Wen-Chen Yeh;José Luis de la Pompa;Mila E. McCurrach;Hong-Bing Shu.
Science (1998)
Requirement for Casper (c-FLIP) in Regulation of Death Receptor–Induced Apoptosis and Embryonic Development
Wen-Chen Yeh;Annick Itie;Andrew J Elia;Michelle Ng.
Immunity (2000)
Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.
Robin Lesley;Ying Xu;Susan L Kalled;Donna M Hess.
Immunity (2004)
Casper is a FADD- and caspase-related inducer of apoptosis.
Hong-Bing Shu;David R Halpin;David V Goeddel.
Immunity (1997)
The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
Hong Bing Shu;Masahiro Takeuchi;David V. Goeddel.
Proceedings of the National Academy of Sciences of the United States of America (1996)
TALL‐1 is a novel member of the TNF family that is down‐regulated by mitogens
Hong-Bing Shu;Wen-Hui Hu;Holly Johnson.
Journal of Leukocyte Biology (1999)
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