World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
70
Citations
86122
World Ranking
2223
National Ranking
279

Overview

Chris Wallace is affiliated with the University of Cambridge in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with significant work also related to Medicine.

Wallace's research interests are concentrated in several subfields and topics. The subfields include Molecular Biology, Genetics, Immunology, Cancer Research, and Hematology. Key topics of their work cover Genetic Associations and Epidemiology, Gene expression and cancer classification, Bioinformatics and Genomic Networks, Genetic Mapping and Diversity in Plants and Animals, Genetic and phenotypic traits in livestock, Single-cell and spatial transcriptomics, and Autoimmune and Inflammatory Disorders Research.

The scientist has contributed to numerous publications, including highly cited papers such as:

  • Mendelian randomization, 2022, Nature Reviews Methods Primers
  • Combining evidence from Mendelian randomization and colocalization: Review and comparison of approaches, 2022, The American Journal of Human Genetics
  • Eliciting priors and relaxing the single causal variant assumption in colocalisation analyses, 2020, PLoS Genetics
  • A more accurate method for colocalisation analysis allowing for multiple causal variants, 2021, PLoS Genetics
  • A disease-associated gene desert directs macrophage inflammation through ETS2, 2024, Nature

Frequent co-authors collaborating with Wallace include:

  • Guillermo Reales
  • Thomas Willis
  • Lucy R. Wedderburn
  • Elena Vigorito
  • Paul Kirk

Their research has been published in a range of venues, most notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • PLoS Genetics
  • The American Journal of Human Genetics
  • Cochrane Database of Systematic Reviews

Best Publications

  • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)

    R C Turner;R R Holman;C A Cull;I M Stratton

  • Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. UK Prospective Diabetes Study Group.

    Stearne;SL Palmer;Hammersley;SL Franklin

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock

  • Bayesian test for colocalisation between pairs of genetic association studies using summary statistics.

    Claudia Giambartolomei;Damjan Vukcevic;Eric E. Schadt;Lude Franke

  • Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 39

    M R Stearne;S L Palmer;M S Hammersley;S L Franklin

  • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

    Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li

  • Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.

    John A. Todd;Neil M. Walker;Jason D. Cooper;Deborah J. Smyth

  • Genome-wide association study identifies eight loci associated with blood pressure

    Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin

  • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

    Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock

  • Correction: Corrigendum: Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis

    John Bowes;Ashley Budu-Aggrey;Ulrike Huffmeier;Steffen Uebe

  • Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters

    Biola M Javierre;Oliver S Burren;Steven P Wilder;Roman Kreuzhuber

  • Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

    Gosia Trynka;Karen A Hunt;Nicholas A Bockett;Jihane Romanos

  • Genome-wide association analysis identifies 20 loci that influence adult height

    M N Weedon;H Lango;C M Lindgren;C M Lindgren;C Wallace

  • Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

    Nick Craddock;Matthew E. Hurles;Niall Cardin;Richard D. Pearson

  • Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.

    Melanie Kolz;Toby Johnson;Toby Johnson;Toby Johnson;Serena Sanna;Alexander Teumer

  • Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.

    Suna Onengut-Gumuscu;Wei-Min Chen;Oliver Burren;Nick J Cooper

  • Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

    Sergey Nejentsev;Joanna M. M. Howson;Neil M. Walker;Jeffrey Szeszko

  • Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

    Cecilia M. Lindgren;Iris M. Heid;Joshua C. Randall;Claudia Lamina

  • Pervasive sharing of genetic effects in autoimmune disease.

    Chris Cotsapas;Benjamin F. Voight;Benjamin F. Voight;Elizabeth Rossin;Kasper Lage;Kasper Lage;Kasper Lage

  • Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

    M. Kolz;T. Johnson;S. Sanna;A. Teumer

Frequent Co-Authors

John A. Todd
John A. Todd University of Oxford
Mark J. Caulfield
Mark J. Caulfield Queen Mary University of London
Patricia B. Munroe
Patricia B. Munroe Queen Mary University of London
Martin Farrall
Martin Farrall University of Oxford
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Deborah J. Smyth
Deborah J. Smyth University of Cambridge
Anna F. Dominiczak
Anna F. Dominiczak University of Glasgow
Willem H. Ouwehand
Willem H. Ouwehand University of Cambridge
Morris J. Brown
Morris J. Brown Queen Mary University of London
Linda S. Wicker
Linda S. Wicker University of Oxford

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