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Deborah J. Smyth

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
23599
World Ranking
11685
National Ranking
900

Deborah J. Smyth publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Deborah J. Smyth sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 95 publications — 4th percentile

4% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Deborah J. Smyth D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Deborah J. Smyth sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 60 D-Index — 41st percentile

41% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Deborah J. Smyth is affiliated with the University of Cambridge in the United Kingdom. Their research focus lies primarily in the fields of Immunology and Microbiology as well as Biochemistry, Genetics, and Molecular Biology. Smyth's expertise covers several subfields, including Immunology, Molecular Biology, Genetics, Oncology, and Cancer Research.

The scientist's recent publications address various aspects of immune cell function and genetic regulation, particularly related to CD4+ T cells and immune disease variants. Notable recent papers include:

  • "Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines," 2020, Nature Communications
  • "Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation," 2022, Nature Genetics
  • "Immune disease variants modulate gene expression in regulatory CD4+ T cells," 2022, Cell Genomics
  • "Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation," 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • "Multiplex melanoma families are enriched for polygenic risk," 2020, Human Molecular Genetics

Smyth frequently collaborates with other researchers, among whom the most common co-authors are Eddie Cano-Gamez, Gosia Trynka, Lara Bossini-Castillo, Blagoje Soskic, and Nikolina Nakić. These collaborations contribute to the advancement of knowledge in immune cell regulation and genetic associations.

The primary publication outlets for Smyth's work include:

  • Zenodo (CERN European Organization for Nuclear Research)
  • Nature Communications
  • Nature Genetics
  • Cell Genomics
  • bioRxiv (Cold Spring Harbor Laboratory)

The main research topics covered in Smyth's body of work are:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Single-cell and spatial transcriptomics
  • Genetic Associations and Epidemiology
  • Epigenetics and DNA Methylation
  • Cutaneous Melanoma Detection and Management
  • Cancer Genomics and Diagnostics

Overall, Smyth's research contributes to understanding the molecular and cellular mechanisms underlying immune responses, particularly through the use of advanced transcriptomic techniques and genetic analysis in the context of disease variants and cancer risk.

Best Publications

  • Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

    H Ueda;Howson Jmm.;L Esposito;J Heward

  • Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

    Jeffrey C Barrett;David G Clayton;Patrick Concannon;Beena Akolkar

  • Common genetic determinants of vitamin D insufficiency: a genome-wide association study

    Thomas J. Wang;Feng Zhang;J. Brent Richards;Bryan Kestenbaum

  • Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.

    John A. Todd;Neil M. Walker;Jason D. Cooper;Deborah J. Smyth

  • Shared and distinct genetic variants in type 1 diabetes and celiac disease.

    Deborah J. Smyth;Vincent Plagnol;Neil M. Walker;Jason D. Cooper

  • Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

    Nick Craddock;Matthew E. Hurles;Niall Cardin;Richard D. Pearson

  • A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region.

    Deborah J Smyth;Jason D Cooper;Rebecca Bailey;Sarah Field

  • Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

    Sergey Nejentsev;Joanna M. M. Howson;Neil M. Walker;Jeffrey Szeszko

  • Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage

    Ivan Angulo;Oscar Vadas;Fabien Garçon;Edward Banham-Hall

  • Replication of an Association Between the Lymphoid Tyrosine Phosphatase Locus (LYP/PTPN22) With Type 1 Diabetes, and Evidence for Its Role as a General Autoimmunity Locus

    Deborah Smyth;Jason D. Cooper;Joanne E. Collins;Joanne M. Heward

  • Population structure, differential bias and genomic control in a large-scale, case-control association study.

    David G Clayton;Neil M Walker;Deborah J Smyth;Rebecca Pask

  • Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.

    Jason D Cooper;Deborah J Smyth;Adam M Smiles;Vincent Plagnol

  • Widespread seasonal gene expression reveals annual differences in human immunity and physiology

    Xaquin Castro Dopico;Marina Evangelou;Ricardo C. Ferreira;Hui Guo

  • Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes

    Christopher E Lowe;Jason D Cooper;Todd Brusko;Neil M Walker

  • The imprinted DLK1 - MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes

    Chris Wallace;Deborah J Smyth;Meeta Maisuria-Armer;Neil M Walker

  • Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes

    Jason D. Cooper;Deborah J. Smyth;Neil M. Walker;Helen Stevens

  • A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes

    Ricardo C. Ferreira;Hui Guo;Richard M R Coulson;Deborah J. Smyth

  • A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

    Matthias Heinig;Enrico Petretto;Chris Wallace;Leonardo Bottolo

  • Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus.

    E Y M G Fung;D J Smyth;J M M Howson;J D Cooper

  • Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases

    Ricardo C. Ferreira;Daniel F. Freitag;Antony J. Cutler;Joanna M. M. Howson

Frequent Co-Authors

John A. Todd
John A. Todd University of Oxford
Jason D. Cooper
Jason D. Cooper AstraZeneca
Linda S. Wicker
Linda S. Wicker University of Oxford
Joanna M. M. Howson
Joanna M. M. Howson Novo Nordisk (United Kingdom)
Chris Wallace
Chris Wallace University of Cambridge
David B. Dunger
David B. Dunger University of Cambridge
David G. Clayton
David G. Clayton University of Cambridge
Vincent Plagnol
Vincent Plagnol University College London
Stephen S. Rich
Stephen S. Rich University of Virginia
Willem H. Ouwehand
Willem H. Ouwehand University of Cambridge

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Best Scientists Citing Deborah J. Smyth

John A. Todd

John A. Todd

University of Oxford

Publications: 144

Hakon Hakonarson

Hakon Hakonarson

Children's Hospital of Philadelphia

Publications: 95

Mark I. McCarthy

Mark I. McCarthy

Genentech

Publications: 86

Jorma Ilonen

Jorma Ilonen

University of Turku

Publications: 85

Flemming Pociot

Flemming Pociot

Steno Diabetes Center

Publications: 85

Cisca Wijmenga

Cisca Wijmenga

University Medical Center Groningen

Publications: 73

Mikael Knip

Mikael Knip

University of Helsinki

Publications: 73

Struan F.A. Grant

Struan F.A. Grant

University of Pennsylvania

Publications: 68

Stephen S. Rich

Stephen S. Rich

University of Virginia

Publications: 66

Jane Worthington

Jane Worthington

University of Manchester

Publications: 66

Peter K. Gregersen

Peter K. Gregersen

Feinstein Institute for Medical Research

Publications: 65

Åke Lernmark

Åke Lernmark

Lund University

Publications: 61

Joel N. Hirschhorn

Joel N. Hirschhorn

Boston Children's Hospital

Publications: 59

Anne Barton

Anne Barton

University of Manchester

Publications: 56

Mark J. Daly

Mark J. Daly

Massachusetts General Hospital

Publications: 55

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Constantin Polychronakos

McGill University Health Centre

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