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Overview

James G. McCormack is affiliated with McC+R&D Consulting Ltd in the United Kingdom. Their research focuses primarily on biochemistry, genetics, and molecular biology, with additional contributions in the field of medicine.

The scientist's work spans several subfields including molecular biology and physiology. Core topics covered in their research include mitochondrial function and pathology, adipose tissue and metabolism, and ATP synthase and ATPases research.

James G. McCormack has published in the Journal of Biological Chemistry, among other venues. A recent publication is titled "The roles of cytosolic and intramitochondrial Ca2+ and the mitochondrial Ca2+-uniporter (MCU) in the stimulation of mammalian oxidative phosphorylation," published in 2020.

  • Guy A. Rutter
  • Andrew P. Halestrap
  • Richard M. Denton

Frequent co-authors working with James G. McCormack include:

  • Guy A. Rutter
  • Andrew P. Halestrap
  • Richard M. Denton

Best Publications

  • Role of calcium ions in regulation of mammalian intramitochondrial metabolism

    J. G. McCormack;A. P. Halestrap;R. M. Denton

  • Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions

    William C. Stanley;Gary D. Lopaschuk;Jennifer L. Hall;James G. McCormack

  • Regulation of energy substrate metabolism in the diabetic heart

    William C Stanley;Gary D Lopaschuk;James G McCormack

  • The effects of calcium ions and adenine nucleotides on the activity of pig heart 2-oxoglutarate dehydrogenase complex.

    J G McCormack;R M Denton

  • On the role of the calcium transport cycle in heart and other mammalian mitochondria

    Richard M. Denton;James G. McCormack

  • Ca2+ As a Second Messenger within Mitochondria of the Heart and other Tissues

    R M Denton;J G McCormack

  • Ca2+ transport by mammalian mitochondria and its role in hormone action.

    R. M. Denton;J. G. McCormack

  • Ranolazine Stimulates Glucose Oxidation in Normoxic, Ischemic, and Reperfused Ischemic Rat Hearts

    James G. McCormack;Rick L. Barr;Andrew A. Wolff;Gary D. Lopaschuk

  • Role of calcium ions in the regulation of intramitochondrial metabolism. Effects of Na+, Mg2+ and ruthenium red on the Ca2+-stimulated oxidation of oxoglutarate and on pyruvate dehydrogenase activity in intact rat heart mitochondria.

    R M Denton;J G McCormack;N J Edgell

  • Proteome Analysis Reveals Phosphorylation of ATP Synthase β-Subunit in Human Skeletal Muscle and Proteins with Potential Roles in Type 2 Diabetes

    Kurt Højlund;Krzysztof Wrzesinski;Peter Mose Larsen;Stephen J. Fey

  • Mitochondrial Ca2+ Transport and the Role of Intramitochondrial Ca2+ in the Regulation of Energy Metabolism

    James G. McCormack;Richard M. Denton

  • Cardioprotective effects of ranolazine (RS-43285) in the isolated perfused rabbit heart

    Michael R Gralinski;Shawn C Black;Kenneth S Kilgore;Arthur Y Chou

  • Regulation of glycogen synthase by glucose and glycogen: a possible role for AMP-activated protein kinase.

    Reza Halse;Lee G.D. Fryer;James G. McCormack;David Carling

  • Studies on mitochondrial Ca2+-transportand matrix Ca2+ using fura-2-loaded rat heart mitochondria

    James G. McCormack;Helen M. Browne;Nicola J. Dawes

  • Pharmacological approaches to inhibit endogenous glucose production as a means of anti-diabetic therapy.

    James G. McCormack;Niels Westergaard;Marit Kristiansen;Christian L. Brand

  • Effects of Tumor Necrosis Factor-α on Insulin Action in Cultured Human Muscle Cells

    Reza Halse;Samantha L. Pearson;James G. McCormack;Stephen J. Yeaman

  • The role of mitochondrial Ca2+ transport and matrix Ca2+ in signal transduction in mammalian tissues

    James G. McCormack;Richard M. Denton

  • Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells

    Emily L. Abbot;James G. McCormack;Christine Reynet;David G. Hassall

  • Direct evidence for a role of intramitochondrial Ca2+ in the regulation of oxidative phosphorylation in the stimulated rat heart. Studies using 31P n.m.r. and ruthenium red

    J F Unitt;J G McCormack;D Reid;L K MacLachlan

  • Ranolazine: a novel metabolic modulator for the treatment of angina.

    James G McCormack;William C Stanley;Andrew A Wolff

Frequent Co-Authors

Richard M. Denton
Richard M. Denton University of Bristol
Guy A. Rutter
Guy A. Rutter Imperial College London
Stephen J. Yeaman
Stephen J. Yeaman Newcastle University
Andrew P. Thomas
Andrew P. Thomas Rutgers, The State University of New Jersey
Andrew P. Halestrap
Andrew P. Halestrap University of Bristol
Peter Roepstorff
Peter Roepstorff University of Southern Denmark
Brian A. Hemmings
Brian A. Hemmings Friedrich Miescher Institute
Victor M. Darley-Usmar
Victor M. Darley-Usmar University of Alabama at Birmingham
David Carling
David Carling Imperial College London

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