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Brian O'Rourke

D-Index & Metrics

Biology and Biochemistry

D-Index
98
Citations
32212
World Ranking
1682
National Ranking
936

Brian O'Rourke publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Brian O'Rourke sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 356 publications — 86th percentile

86% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Brian O'Rourke D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Brian O'Rourke sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 98 D-Index — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Brian O'Rourke is affiliated with Johns Hopkins University in the United States. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology, with notable specialization in molecular biology, cardiology and cardiovascular medicine, pathology and forensic medicine, physiology, and surgery.

The main topics of Brian O'Rourke's work include mitochondrial function and pathology, cardiac ischemia and reperfusion, mesenchymal stem cell research, tissue engineering and regenerative medicine, adipose tissue and metabolism, cardiovascular function and risk factors, and cardiac electrophysiology and arrhythmias.

Frequent publication venues for their work include Circulation Research, bioRxiv (Cold Spring Harbor Laboratory), Biophysical Journal, Journal of Molecular and Cellular Cardiology, and Journal of Biological Chemistry.

Notable recent papers by Brian O'Rourke are as follows:

  • ATM-CHK 2-Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress, 2020, The EMBO Journal
  • Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs, 2020, Genome Medicine
  • Blood-derived mitochondrial DNA copy number is associated with gene expression across multiple tissues and is predictive for incident neurodegenerative disease, 2021, Genome Research
  • MCU Overexpression Rescues Inotropy and Reverses Heart Failure by Reducing SR Ca 2+ Leak, 2021, Circulation Research
  • Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy, 2021, Science Translational Medicine

Frequent coauthors collaborating with Brian O'Rourke include Deepthi Ashok, Ting Liu, Kyriakos N. Papanicolaou, D. Brian Foster, and Rita N. Bárcia.

Best Publications

  • Mitochondrial ATP-Dependent Potassium Channels Novel Effectors of Cardioprotection?

    Yongge Liu;Toshiaki Sato;Brian O’Rourke;Eduardo Marban

  • Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms.

    Lili A. Barouch;Robert W. Harrison;Michael W. Skaf;Gisele O. Rosas

  • Mechanisms of Altered Excitation-Contraction Coupling in Canine Tachycardia-Induced Heart Failure, II Model Studies

    Raimond L. Winslow;Jeremy Rice;Saleet Jafri;Eduardo Marbán

  • Sudden Cardiac Death Prediction and Prevention: Report From a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop

    Glenn I. Fishman;Sumeet S. Chugh;John P. Dimarco;Christine M. Albert

  • Ionic Mechanism of Action Potential Prolongation in Ventricular Myocytes From Dogs With Pacing-Induced Heart Failure

    Stefan Kääb;H. Bradley Nuss;Nipavan Chiamvimonvat;Brian O'Rourke

  • Cytoprotective role of Ca2+- activated K+ channels in the cardiac inner mitochondrial membrane.

    Wenhong Xu;Yongge Liu;Sheng Wang;Todd McDonald

  • Synchronized Whole Cell Oscillations in Mitochondrial Metabolism Triggered by a Local Release of Reactive Oxygen Species in Cardiac Myocytes

    Miguel A. Aon;Sonia Cortassa;Eduardo Marbán;Brian O'Rourke

  • Evidence for Mitochondrial K+ Channels and Their Role in Cardioprotection

    Brian O’Rourke

  • Mitochondrial ATP-Sensitive Potassium Channels Attenuate Matrix Ca2+ Overload During Simulated Ischemia and Reperfusion: Possible Mechanism of Cardioprotection

    Mitsushige Murata;Masaharu Akao;Brian O'Rourke;Eduardo Marbán

  • Nitric Oxide Regulates Exocytosis by S-Nitrosylation of N-ethylmaleimide-Sensitive Factor

    Kenji Matsushita;Craig N Morrell;Beatrice Cambien;Shui Xiang Yang

  • Myocardial KATP Channels in Preconditioning

    Brian O’Rourke

  • An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics

    Sonia Cortassa;Miguel A. Aon;Eduardo Marbán;Raimond L. Winslow

  • ACTIVATION OF MITOCHONDRIAL ATP-DEPENDENT POTASSIUM CHANNELS BY NITRIC OXIDE

    Norihito Sasaki;Toshiaki Sato;Andreas Ohler;Brian O’Rourke

  • Modulation of Mitochondrial ATP-Dependent K+ Channels by Protein Kinase C

    Toshiaki Sato;Brian O’Rourke;Eduardo Marbán

  • Elevated Cytosolic Na+ Decreases Mitochondrial Ca2+ Uptake During Excitation-Contraction Coupling and Impairs Energetic Adaptation in Cardiac Myocytes

    Christoph Maack;Sonia Cortassa;Miguel A. Aon;Anand N. Ganesan

  • Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cells

    Masaharu Akao;Andreas Ohler;Andreas Ohler;Brian O’Rourke;Eduardo Marbán

  • Mitochondrial Ion Channels

    Brian O’Rourke

  • Redox-optimized ROS balance: A unifying hypothesis

    M.A. Aon;S. Cortassa;B. O'Rourke

  • Oscillations of membrane current and excitability driven by metabolic oscillations in heart cells

    Brian O'Rourke;Brian M. Ramza;Eduardo Marban

  • The mitochondrial origin of postischemic arrhythmias

    Fadi G. Akar;Miguel A. Aon;Gordon F. Tomaselli;Brian O’Rourke

Frequent Co-Authors

Miguel A. Aon
Miguel A. Aon National Institutes of Health
Sonia Cortassa
Sonia Cortassa National Institutes of Health
Eduardo Marbán
Eduardo Marbán Cedars-Sinai Medical Center
David A. Kass
David A. Kass Johns Hopkins University School of Medicine
Gordon F. Tomaselli
Gordon F. Tomaselli Johns Hopkins University
Jennifer E. Van Eyk
Jennifer E. Van Eyk Cedars-Sinai Medical Center
Robert N. Cole
Robert N. Cole Johns Hopkins University School of Medicine
Charles Steenbergen
Charles Steenbergen Johns Hopkins University
Nona Sotoodehnia
Nona Sotoodehnia University of Washington
Nathan Pankratz
Nathan Pankratz University of Minnesota

External Links

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Best Scientists Citing Brian O'Rourke

Donald M. Bers

Donald M. Bers

University of California, Davis

Publications: 90

David A. Kass

David A. Kass

Johns Hopkins University School of Medicine

Publications: 76

Eduardo Marbán

Eduardo Marbán

Cedars-Sinai Medical Center

Publications: 76

Stanley Nattel

Stanley Nattel

Montreal Heart Institute

Publications: 61

Andre Terzic

Andre Terzic

Mayo Clinic

Publications: 52

Gordon F. Tomaselli

Gordon F. Tomaselli

Johns Hopkins University

Publications: 51

David F. Stowe

David F. Stowe

Medical College of Wisconsin

Publications: 50

Elizabeth Murphy

Elizabeth Murphy

National Heart Lung and Blood Institute

Publications: 50

Joshua M. Hare

Joshua M. Hare

University of Miami

Publications: 46

Miguel A. Aon

Miguel A. Aon

National Institutes of Health

Publications: 43

Derek M. Yellon

Derek M. Yellon

University College London

Publications: 43

Gerd Heusch

Gerd Heusch

University of Duisburg-Essen

Publications: 43

James N. Weiss

James N. Weiss

University of California, Los Angeles

Publications: 42

Jennifer E. Van Eyk

Jennifer E. Van Eyk

Cedars-Sinai Medical Center

Publications: 40

Zhilin Qu

Zhilin Qu

University of California, Los Angeles

Publications: 38

Rainer Schulz

Rainer Schulz

University of Giessen

Publications: 38

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