Derek M. Yellon spends much of his time researching Internal medicine, Ischemia, Ischemic preconditioning, Reperfusion injury and Cardiology. His research combines Endocrinology and Internal medicine. His studies in Ischemia integrate themes in fields like Circulatory system, Biochemistry, Pharmacology and MAPK/ERK pathway.
His Ischemic preconditioning study incorporates themes from Anesthesia, Adenosine, Adenosine receptor, Heart metabolism and Infarction. The Reperfusion injury study combines topics in areas such as Reperfusion therapy, Protein kinase B, Cardioprotection, Nitric oxide and Mitochondrial permeability transition pore. His Cardioprotection study integrates concerns from other disciplines, such as Intensive care medicine, Signal transduction, Kinase, Cell biology and Cardiovascular agent.
The scientist’s investigation covers issues in Internal medicine, Cardiology, Ischemia, Cardioprotection and Myocardial infarction. His Internal medicine study often links to related topics such as Endocrinology. The study incorporates disciplines such as Anesthesia, Adenosine, Pharmacology and In vivo in addition to Ischemia.
His Cardioprotection research incorporates elements of Immunology, Signal transduction, Cell biology and Mitochondrial permeability transition pore. His work deals with themes such as Diabetes mellitus, Cause of death and Heart failure, which intersect with Myocardial infarction. His research investigates the link between Reperfusion injury and topics such as Protein kinase B that cross with problems in Kinase.
Internal medicine, Cardioprotection, Cardiology, Myocardial infarction and Ischemia are his primary areas of study. His biological study spans a wide range of topics, including Endocrinology and Surgery. His study in Cardioprotection is interdisciplinary in nature, drawing from both Anesthesia, Infarct size, Immunology, Intensive care medicine and Ischemic preconditioning.
His work carried out in the field of Cardiology brings together such families of science as Clinical trial and Neuroprotection. His research investigates the connection between Myocardial infarction and topics such as Diabetes mellitus that intersect with issues in Perfusion. The concepts of his Ischemia study are interwoven with issues in Blood flow, Pharmacology and Cell biology.
Derek M. Yellon mainly investigates Cardioprotection, Myocardial infarction, Internal medicine, Ischemia and Cardiology. His Cardioprotection study combines topics in areas such as Immunology, Intensive care medicine, Reperfusion injury, Pharmacology and Ischemic preconditioning. Many of his research projects under Myocardial infarction are closely connected to In patient with In patient, tying the diverse disciplines of science together.
His research integrates issues of Endocrinology and Mitochondrial permeability transition pore in his study of Internal medicine. His research investigates the connection between Ischemia and topics such as Cell biology that intersect with problems in Position paper and Artery. His Cardiology study focuses on Heart failure in particular.
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Myocardial Reperfusion Injury
Derek M Yellon;Derek J Hausenloy.
The New England Journal of Medicine (2007)
Myocardial ischemia-reperfusion injury: a neglected therapeutic target
Derek J. Hausenloy;Derek M. Yellon.
Journal of Clinical Investigation (2013)
Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction.
M S Marber;D S Latchman;J M Walker;D M Yellon.
Preconditioning the Myocardium: From Cellular Physiology to Clinical Cardiology
Derek M. Yellon;James M. Downey.
Physiological Reviews (2003)
The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia, infarction, and reperfusion
M J A Walker;M J Curtis;D J Hearse;R W F Campbell.
Cardiovascular Research (1988)
New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway.
Derek J Hausenloy;Derek M Yellon.
Cardiovascular Research (2004)
Postconditioning: A Form of “Modified Reperfusion” Protects the Myocardium by Activating the Phosphatidylinositol 3-Kinase-Akt Pathway
Andrew Tsang;Derek J. Hausenloy;Mihaela M. Mocanu;Derek M. Yellon.
Circulation Research (2004)
Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury.
M. S. Marber;R. Mestril;Shun-Hua Chi;M. R. Sayen.
Journal of Clinical Investigation (1995)
Preconditioning the human myocardium
D.M Yellon;A.M Alkhulaifi;W.B Pugsley.
The Lancet (1993)
Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury
Sang Bing Ong;Sapna Subrayan;Shiang Y. Lim;Derek M. Yellon.
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