What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
His primary areas of investigation include Mitochondrion, Biochemistry, Internal medicine, Endocrinology and Ischemic preconditioning.
His Mitochondrion research is included under the broader classification of Cell biology.
The study incorporates disciplines such as Proinflammatory cytokine, Inflammation, Lipopolysaccharide and Immunology in addition to Cell biology.
His work deals with themes such as Parkin, Naltrindole and Antioxidant, which intersect with Endocrinology.
Michael N. Sack combines subjects such as Agonist, Oxidative phosphorylation, Cardioprotection and Pharmacology with his study of Ischemic preconditioning.
Michael N. Sack has included themes like Receptor, Opioid receptor, DADLE, Insulin and Kinase in his Cardioprotection study.
His most cited work include:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
- Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS) (585 citations)
- Fatty Acid Oxidation Enzyme Gene Expression Is Downregulated in the Failing Heart (547 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Cell biology, Mitochondrion, Internal medicine, Endocrinology and Biochemistry.
His studies in Cell biology integrate themes in fields like Autophagy and Molecular biology.
His research in Mitochondrion intersects with topics in Oxidative phosphorylation, SIRT3, Sirtuin and Ischemia.
The various areas that Michael N. Sack examines in his Internal medicine study include Diabetes mellitus and Cardiology.
His study explores the link between Endocrinology and topics such as Signal transduction that cross with problems in Receptor.
His Cardioprotection course of study focuses on Ischemic preconditioning and Diazoxide, Tumor necrosis factor alpha, Phenotype, Adenosine and Respiratory system.
He most often published in these fields:
- Cell biology (39.10%)
- Mitochondrion (35.26%)
- Internal medicine (33.33%)
What were the highlights of his more recent work (between 2018-2021)?
- Cell biology (39.10%)
- Internal medicine (33.33%)
- Acetylation (14.74%)
In recent papers he was focusing on the following fields of study:
Michael N. Sack mostly deals with Cell biology, Internal medicine, Acetylation, Endocrinology and mTORC1.
His Cell biology study integrates concerns from other disciplines, such as Autophagy, Biogenesis, Lysosome, Reperfusion injury and Cell type.
His research links Cardiology with Internal medicine.
While the research belongs to areas of Cardiology, Michael N. Sack spends his time largely on the problem of Lung, intersecting his research to questions surrounding Mitochondrion.
His Acetylation research is multidisciplinary, incorporating perspectives in Enzyme assay, Reactive oxygen species, SOD2 and Pyruvate dehydrogenase complex.
His biological study focuses on Intermittent fasting.
Between 2018 and 2021, his most popular works were:
- Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop (20 citations)
- Loss of GCN5L1 in cardiac cells disrupts glucose metabolism and promotes cell death via reduced Akt/mTORC2 signaling. (11 citations)
- Cardiac-specific deletion of GCN5L1 restricts recovery from ischemia-reperfusion injury. (8 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
Michael N. Sack mainly investigates Cell biology, Mitochondrion, Cell type, Reperfusion injury and Acetylation.
His study in the field of mTORC1, Signal transduction and Regeneration is also linked to topics like Glutaminase.
His study in Mitochondrion is interdisciplinary in nature, drawing from both Heart failure, Pathogenesis, Cardiology, Internal medicine and Lung.
The Cell type study combines topics in areas such as Cardiac function curve, Mitogen-activated protein kinase, Reactive oxygen species, Viability assay and Ischemia.
The concepts of his Reperfusion injury study are interwoven with issues in Gene knockdown, mTORC2, Glycolysis, Mitochondrial ROS and Programmed cell death.
His Acetylation research incorporates elements of Histone, Protein subunit, Intracellular and Cytosol.
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