His main research concerns Virology, Coronavirus, Antibody, Protein folding and Epitope. Yee-Joo Tan works mostly in the field of Virology, limiting it down to concerns involving Molecular biology and, occasionally, Complementary DNA, Transfection and Open reading frame. Yee-Joo Tan interconnects Fusion protein, Antigen and Vaccination in the investigation of issues within Antibody.
His studies examine the connections between Protein folding and genetics, as well as such issues in Crystallography, with regards to Two state folding, Biophysics and Protein aggregation. His Epitope study combines topics in areas such as T cell and Virus. To a larger extent, Yee-Joo Tan studies Programmed cell death with the aim of understanding Caspase 3.
Yee-Joo Tan spends much of his time researching Virology, Virus, Antibody, Molecular biology and Coronavirus. His research integrates issues of Epitope, Immunology and Monoclonal antibody in his study of Virology. His work on Serology is typically connected to Severe acute respiratory syndrome coronavirus 2 as part of general Antibody study, connecting several disciplines of science.
As part of the same scientific family, Yee-Joo Tan usually focuses on Molecular biology, concentrating on Peptide sequence and intersecting with Plasma protein binding. His study in Viral replication is interdisciplinary in nature, drawing from both RNA and Cell biology. His research in Cell biology intersects with topics in Apoptosis, Programmed cell death and Immunoprecipitation.
Virology, Antibody, Virus, Monoclonal antibody and T cell are his primary areas of study. He studies Virology, namely Outbreak. His Outbreak research includes themes of Cytotoxic T cell, Immunodominance, Common cold and Pathogenesis.
His Antibody study incorporates themes from Immune system and Zika virus. Yee-Joo Tan combines subjects such as Transcriptional activity and Minichromosome with his study of Virus. The concepts of his Monoclonal antibody study are interwoven with issues in Influenza A virus subtype H5N1 and Nucleolus, Cell biology, Cytoplasm.
His primary scientific interests are in Virology, Antibody, Serology, Outbreak and Herd immunity. In most of his Virology studies, his work intersects topics such as Common cold. When carried out as part of a general Antibody research project, his work on Vaccine efficacy is frequently linked to work in Pandemic and Severe acute respiratory syndrome coronavirus 2, therefore connecting diverse disciplines of study.
His Vaccine efficacy research is multidisciplinary, incorporating elements of Biosafety level, Isotype and Cross neutralization. The various areas that Yee-Joo Tan examines in his Outbreak study include Epitope, Cytotoxic T cell, Immunodominance, T cell and Pathogenesis. He has researched Herd immunity in several fields, including Virus, Asymptomatic and Disease.
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Autophagy (2016)
SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls.
Nina Le Bert;Anthony T Tan;Kamini Kunasegaran;Christine Y L Tham.
Nature (2020)
A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2-spike protein-protein interaction.
Chee Wah Tan;Wan Ni Chia;Xijian Qin;Pei Liu.
Nature Biotechnology (2020)
Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection.
Oi Wing Ng;Adeline Chia;Anthony T. Tan;Ramesh S. Jadi.
Vaccine (2016)
Negative activation enthalpies in the kinetics of protein folding.
Mikael Oliveberg;Yee-Joo Tan;Alan R. Fersht.
Proceedings of the National Academy of Sciences of the United States of America (1995)
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Autophagy (2016)
Overexpression of 7a, a Protein Specifically Encoded by the Severe Acute Respiratory Syndrome Coronavirus, Induces Apoptosis via a Caspase-Dependent Pathway
Yee Joo Tan;Burtram C. Fielding;Phuay Yee Goh;Shuo Shen.
Journal of Virology (2004)
Dual effect of nitric oxide on SARS-CoV replication: viral RNA production and palmitoylation of the S protein are affected.
Sara Åkerström;Vithiagaran Gunalan;Choong Tat Keng;Yee Joo Tan.
Virology (2009)
Protein folding from a highly disordered denatured state: The folding pathway of chymotrypsin inhibitor 2 at atomic resolution
Steven L. Kazmirski;Kam Bo Wong;Stefan M V Freund;Yee Joo Tan.
Proceedings of the National Academy of Sciences of the United States of America (2001)
The Changing Nature of the Protein Folding Transition State: Implications for the Shape of the Free-energy Profile for Folding
Mikael Oliveberg;Yee-Joo Tan;Maria Silow;Alan R Fersht.
Journal of Molecular Biology (1998)
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