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Biology and Biochemistry

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54
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17245
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15381
National Ranking
57

Overview

Barnaby Young is affiliated with the National Centre for Infectious Diseases in Singapore. Their research primarily focuses on medicine, with a particular emphasis on infectious diseases, neurology, epidemiology, animal science and zoology, and immunology.

The scientist's research addresses a range of topics including COVID-19 clinical research studies, SARS-CoV-2 and COVID-19 research, long-term effects of COVID-19, SARS-CoV-2 detection and testing, animal virus infection studies, COVID-19 epidemiological studies, and viral gastroenteritis research and epidemiology.

Recent publications authored or co-authored by Barnaby Young include:

  • "Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore" (2020, JAMA)
  • "A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2-spike protein-protein interaction" (2020, Nature Biotechnology)
  • "Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients" (2020, Nature Communications)
  • "Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients" (2021, Cell Reports)
  • "Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures" (2020, The Lancet)

Frequent co-authors collaborating with Barnaby Young include:

  • David Chien Lye
  • Yee-Sin Leo
  • Laurent Rénia
  • Lisa F. P. Ng
  • Siew-Wai Fong

Publications have appeared in various venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • SSRN Electronic Journal
  • Open Forum Infectious Diseases
  • Clinical Microbiology and Infection
  • Research Square (Research Square)

The scientist's body of work spans over 500 publications in medicine, with 317 specifically addressing infectious diseases. Other significant subfields include neurology with 48 publications, epidemiology with 44, animal science and zoology with 21, and immunology with 19.

This researcher's work contributes to understanding the clinical and epidemiological aspects of COVID-19, testing methods for SARS-CoV-2, and the long-term impacts of the virus. Their collaboration across multiple disciplines and frequent publication in high-profile scientific venues reflects a broad engagement with ongoing research challenges within infectious diseases and related medical fields.

Best Publications

  • Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore.

    Barnaby Edward Young;Sean Wei Xiang Ong;Shirin Kalimuddin;Shirin Kalimuddin;Jenny G. Low;Jenny G. Low

  • A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2-spike protein-protein interaction.

    Chee Wah Tan;Wan Ni Chia;Xijian Qin;Pei Liu

  • Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients.

    Po Ying Chia;Po Ying Chia;Kristen Kelli Coleman;Yian Kim Tan;Sean Wei Xiang Ong

  • Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures.

    Rachael Pung;Calvin J. Chiew;Barnaby E. Young;Sarah Chin

  • Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients.

    Anthony T. Tan;Martin Linster;Chee Wah Tan;Nina Le Bert

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • Clinical and virological features of SARS-CoV-2 variants of concern: a retrospective cohort study comparing B.1.1.7 (Alpha), B.1.315 (Beta), and B.1.617.2 (Delta).

    Sean Wei Xiang Ong;Calvin J Chiew;Li Wei Ang;Tze-Minn Mak

  • Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients.

    Chek Meng Poh;Guillaume Carissimo;Bei Wang;Siti Naqiah Amrun

  • Assessing Viral Shedding and Infectivity of Tears in Coronavirus Disease 2019 (COVID-19) Patients.

    Ivan Yu Jun Seah;Danielle E. Anderson;Adrian Eng Zheng Kang;Linfa Wang

  • Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study.

    Barnaby E Young;Barnaby E Young;Siew-Wai Fong;Siew-Wai Fong;Yi-Hao Chan;Tze-Minn Mak

  • Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine-breakthrough infections: a multi-center cohort study

    Po Ying Chia;Po Ying Chia;Sean Wei Xiang Ong;Calvin J. Chiew;Li Wei Ang

  • Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study.

    Wan Ni Chia;Feng Zhu;Sean Wei Xiang Ong;Barnaby Edward Young;Barnaby Edward Young

  • Hybrid metagenomic assembly enables high-resolution analysis of resistance determinants and mobile elements in human microbiomes

    Denis Bertrand;Jim Shaw;Manesh Kalathiyappan;Amanda Hui Qi Ng

  • Risk Factors for Severe Disease and Efficacy of Treatment in Patients Infected With COVID-19: A Systematic Review, Meta-Analysis, and Meta-Regression Analysis.

    John J Y Zhang;Keng Siang Lee;Li Wei Ang;Yee Sin Leo

  • Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial

    Steven Y.C. Tong;Steven Y.C. Tong;David C. Lye;Dafna Yahav;Dafna Yahav;Archana Sud;Archana Sud

  • Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2.

    Yvonne C. F. Su;Danielle E. Anderson;Barnaby E. Young;Martin Linster

  • Epidemiological and Clinical Predictors of COVID-19.

    Yinxiaohe Sun;Vanessa Koh;Kalisvar Marimuthu;Kalisvar Marimuthu;Oon Tek Ng;Oon Tek Ng

  • Viral Dynamics and Immune Correlates of Coronavirus Disease 2019 (COVID-19) Severity.

    Barnaby E Young;Barnaby E Young;Sean W X Ong;Lisa F P Ng;Danielle E Anderson

  • Efficacy of 400 mg efavirenz versus standard 600 mg dose in HIV-infected, antiretroviral-naive adults (ENCORE1): a randomised, double-blind, placebo-controlled, non-inferiority trial.

    Rebekah L. Puls;Janaki Amin;Marcelo Losso;Praphan Phanuphak

  • Pan-Sarbecovirus Neutralizing Antibodies in BNT162b2-Immunized SARS-CoV-1 Survivors.

    Chee-Wah Tan;Wan-Ni Chia;Barnaby E. Young;Feng Zhu

Frequent Co-Authors

David C. Lye
David C. Lye Tan Tock Seng Hospital
Yee Sin Leo
Yee Sin Leo Nanyang Technological University
Lisa F. P. Ng
Lisa F. P. Ng Agency for Science, Technology and Research
Laurent Rénia
Laurent Rénia Nanyang Technological University
Raymond T. P. Lin
Raymond T. P. Lin National University of Singapore
Lin-Fa Wang
Lin-Fa Wang Duke NUS Graduate Medical School
Paul A. Tambyah
Paul A. Tambyah National University of Singapore
Vernon J. Lee
Vernon J. Lee Ministry of Health
Sebastian Maurer-Stroh
Sebastian Maurer-Stroh Agency for Science, Technology and Research
Annelies Wilder-Smith
Annelies Wilder-Smith University of Bern

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