Kelvin K. W. To

Overview

Best Publications

• A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.

  Jasper Fuk Woo Chan;Shuofeng Yuan;Kin Hang Kok;Kelvin Kai Wang To;Kelvin Kai Wang To

  10687
  Citations

• Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study.

  Kelvin Kai Wang To;Owen Tak Yin Tsang;Wai Shing Leung;Anthony Raymond Tam

  3620
  Citations

• Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan.

  Jasper Fuk Woo Chan;Kin Hang Kok;Kin Hang Kok;Zheng Zhu;Hin Chu;Hin Chu

  3363
  Citations

• Consistent Detection of 2019 Novel Coronavirus in Saliva.

  Kelvin Kai Wang To;Kelvin Kai Wang To;Kelvin Kai Wang To;Owen Tak Yin Tsang;Cyril Chik-Yan Yip;Cyril Chik-Yan Yip;Kwok Hung Chan

  2593
  Citations

• Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2

  Unknown

  2383
  Citations

• Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples From a Hong Kong Cohort: Systematic Review and Meta-analysis.

  Ka Shing Cheung;Ivan F.N. Hung;Pierre P.Y. Chan;K. C. Lung

  1867
  Citations

• Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial.

  Ivan Fan Ngai Hung;Kwok Cheung Lung;Eugene Yuk Keung Tso;Raymond Liu

  1765
  Citations

• Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility.

  Jasper Fuk Woo Chan;Jasper Fuk Woo Chan;Jasper Fuk Woo Chan;Anna Jinxia Zhang;Shuofeng Yuan;Vincent Kwok Man Poon

  1347
  Citations

• Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated In Vitro and with Clinical Specimens.

  Jasper Fuk-Woo Chan;Cyril Chik-Yan Yip;Kelvin Kai-Wang To;Tommy Hing-Cheung Tang

  1121
  Citations

• Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome

  Yu Chen;Weifeng Liang;Shigui Yang;Nanping Wu

  1084
  Citations

• Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease

  Jasper F. W. Chan;Susanna K. P. Lau;Kelvin K. W. To;Vincent C. C. Cheng

  1043
  Citations

• Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study.

  Hin Chu;Jasper Fuk-Woo Chan;Jasper Fuk-Woo Chan;Terrence Tsz-Tai Yuen;Huiping Shuai

  967
  Citations

• The role of community-wide wearing of face mask for control of coronavirus disease 2019 (COVID-19) epidemic due to SARS-CoV-2.

  Vincent Chi Chung Cheng;Shuk Ching Wong;Vivien Wai Man Chuang;Simon Yung Chun So

  931
  Citations

• Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection

  Ivan Fn Hung;Kelvin Kw To;Cheuk-Kwong Lee;Kar-Lung Lee

  809
  Citations

• Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data.

  Stella G Muthuri;Sudhir Venkatesan;Puja R Myles;Jo Leonardi-Bee

  793
  Citations

• Coronavirus Disease 2019 (COVID-19) Re-infection by a Phylogenetically Distinct Severe Acute Respiratory Syndrome Coronavirus 2 Strain Confirmed by Whole Genome Sequencing.

  Kelvin Kai-Wang To;Kelvin Kai-Wang To;Ivan Fan-Ngai Hung;Jonathan Daniel Ip;Allen Wing-Ho Chu

  741
  Citations

• SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells

  Unknown

  740
  Citations

• Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19.

  Hin Chu;Jasper Fuk-Woo Chan;Yixin Wang;Terrence Tsz-Tai Yuen

  723
  Citations

• Interspecies transmission and emergence of novel viruses: lessons from bats and birds.

  Jasper Fuk Woo Chan;Kelvin Kai Wang To;Herman Tse;Dong Yan Jin

  716
  Citations

• Neutralization of SARS-CoV-2 Omicron variant by sera from BNT162b2 or Coronavac vaccine recipients

  Unknown

  693
  Citations

• Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses

  Runhong Zhou;Kelvin Kai Wang To;Yik Chun Wong;Li Liu

  629
  Citations

• Infection of bat and human intestinal organoids by SARS-CoV-2.

  Jie Zhou;Cun Li;Xiaojuan Liu;Man Chun Chiu

  624
  Citations

• Active Replication of Middle East Respiratory Syndrome Coronavirus and Aberrant Induction of Inflammatory Cytokines and Chemokines in Human Macrophages: Implications for Pathogenesis

  Jie Zhou;Hin Chu;Cun Li;Bosco Ho-Yin Wong

  545
  Citations

• SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists.

  Chun Kit Yuen;Chun Kit Yuen;Joy Yan Lam;Joy Yan Lam;Wan Man Wong;Wan Man Wong;Long Fung Mak;Long Fung Mak

  521
  Citations

• Delayed Clearance of Viral Load and Marked Cytokine Activation in Severe Cases of Pandemic H1N1 2009 Influenza Virus Infection

  Kelvin K. W. To;Ivan F. N. Hung;Iris W. S. Li;Kar-Lung Lee

  503
  Citations

• Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways

  Hin Chu;Jie Zhou;Bosco Ho-Yin Wong;Cun Li

  473
  Citations