World's Best Scientists 2026 revealed!
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Immunology
Japan
2026
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Medicine
Japan
2026

D-Index & Metrics

Immunology

D-Index
162
Citations
100821
World Ranking
72
National Ranking
5

Medicine

D-Index
162
Citations
100979
World Ranking
712
National Ranking
10

Research.com Recognitions

  • 2026 - Research.com Immunology in Japan Leader Award
  • 2026 - Research.com Medicine in Japan Leader Award
  • 2025 - Research.com Immunology in Japan Leader Award
  • 2023 - Research.com Immunology in Japan Leader Award
  • 2023 - Research.com Medicine in Japan Leader Award
  • 2022 - Research.com Immunology in Japan Leader Award
  • 2022 - Research.com Medicine in Japan Leader Award

Overview

Yoichiro Iwakura is affiliated with the Tokyo University of Science in Japan. Their research focuses predominantly on medicine and immunology, with a significant number of publications in related fields such as molecular biology, epidemiology, oncology, and pharmacology.

The scientist's work spans several key topics, including:

  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Immune Response and Inflammation
  • T-cell and B-cell Immunology
  • IL-33, ST2, and ILC Pathways
  • Antifungal resistance and susceptibility
  • Dermatology and Skin Diseases

They have contributed to multiple papers of note, including:

  • Gasdermin D-mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma, 2022, Science Immunology
  • Obesity accelerates hair thinning by stem cell-centric converging mechanisms, 2021, Nature
  • An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity, 2022, Cell
  • Arthritis flares mediated by tissue-resident memory T cells in the joint, 2021, Cell Reports
  • Interleukin-17 family members in health and disease, 2021, International Immunology

Frequent co-authors collaborating with Iwakura include:

  • Shinobu Saijo (9 publications)
  • Yoshiyuki Adachi (7 publications)
  • Ko Sato (7 publications)
  • Emi Kanno (7 publications)
  • Hiromasa Tanno (7 publications)

The scientist's research is published in several prominent venues such as:

  • Scientific Reports (7 publications)
  • Nature Communications (6 publications)
  • Frontiers in Immunology (6 publications)
  • International Journal of Molecular Sciences (4 publications)
  • Cell Reports (3 publications)

Best Publications

  • Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

    Shin Yoshimoto;Tze Mun Loo;Tze Mun Loo;Koji Atarashi;Hiroaki Kanda

  • IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis

    Yutaka Komiyama;Susumu Nakae;Taizo Matsuki;Aya Nambu

  • Suppression of Immune Induction of Collagen-Induced Arthritis in IL-17-Deficient Mice

    Susumu Nakae;Aya Nambu;Katsuko Sudo;Yoichiro Iwakura

  • Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

    Kojiro Sato;Ayako Suematsu;Kazuo Okamoto;Akira Yamaguchi

  • Functional Specialization of Interleukin-17 Family Members

    Yoichiro Iwakura;Harumichi Ishigame;Shinobu Saijo;Susumu Nakae

  • Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses

    Susumu Nakae;Yutaka Komiyama;Aya Nambu;Katsuko Sudo

  • Essential role of MD-2 in LPS responsiveness and TLR4 distribution.

    Yoshinori Nagai;Sachiko Akashi;Masakazu Nagafuku;Masato Ogata

  • IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

    Shean J Aujla;Yvonne R Chan;Mingquan Zheng;Mingjian Fei

  • The IL-23/IL-17 axis in inflammation

    Yoichiro Iwakura;Harumichi Ishigame

  • IL-1 is required for tumor invasiveness and angiogenesis

    Elena Voronov;Dror S. Shouval;Yakov Krelin;Emanuela Cagnano

  • Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses

    Harumichi Ishigame;Shigeru Kakuta;Takeshi Nagai;Motohiko Kadoki

  • Development of Chronic Inflammatory Arthropathy Resembling Rheumatoid Arthritis in Interleukin 1 Receptor Antagonist–Deficient Mice

    Reiko Horai;Shinobu Saijo;Hidetoshi Tanioka;Susumu Nakae

  • Lack of Interleukin-1β Decreases the Severity of Atherosclerosis in ApoE-Deficient Mice

    Hirokazu Kirii;Tamikazu Niwa;Yasuhiro Yamada;Hisayasu Wada

  • Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury.

    Takashi Shichita;Yuki Sugiyama;Hiroaki Ooboshi;Hiroaki Ooboshi;Hiroshi Sugimori

  • Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells.

    Kazuyoshi Takeda;Yoshihiro Hayakawa;Mark J. Smyth;Nobuhiko Kayagaki

  • A protective function for interleukin 17A in T cell–mediated intestinal inflammation

    William O'Connor;Masahito Kamanaka;Carmen J Booth;Terrence Town;Terrence Town

  • Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction

    Meena S. Madhur;Heinrich E. Lob;Louise A. McCann;Yoichiro Iwakura

  • Production of Mice Deficient in Genes for Interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 Receptor Antagonist Shows that IL-1β Is Crucial in Turpentine-induced Fever Development and Glucocorticoid Secretion

    Reiko Horai;Masahide Asano;Katsuko Sudo;Hirotaka Kanuka

  • Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans.

    Shinobu Saijo;Noriyuki Fujikado;Takahisa Furuta;Soo Hyun Chung

  • Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

    Shinobu Saijo;Satoshi Ikeda;Keiko Yamabe;Shigeru Kakuta

Frequent Co-Authors

Shinobu Saijo
Shinobu Saijo Chiba University
Masahide Asano
Masahide Asano Kyoto University
Katsuko Sudo
Katsuko Sudo Tokyo Medical University
Susumu Nakae
Susumu Nakae Hiroshima University
Naohito Ohno
Naohito Ohno Tokyo University of Pharmacy and Life Sciences
Shizuo Akira
Shizuo Akira Osaka University
Seiji Shioda
Seiji Shioda Shonan University of Medical Sciences
Akio Nakane
Akio Nakane Hirosaki University
Kiyoshi Takeda
Kiyoshi Takeda Osaka University
Yoshiyuki Adachi
Yoshiyuki Adachi Tokyo University of Pharmacy and Life Sciences

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Related Online Degrees & Career Pathways

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Overall, combining immunology studies with targeted nursing education can enhance career opportunities, especially for those aiming to work in clinical settings or healthcare research focusing on immune system disorders.

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