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Immunology

D-Index
67
Citations
15924
World Ranking
2668
National Ranking
107

Overview

Naohito Ohno is affiliated with Tokyo University of Pharmacy and Life Sciences in Japan. Their research spans multiple fields including Medicine, Biochemistry, Genetics and Molecular Biology, and Agricultural and Biological Sciences. Their work also covers subfields such as Plant Science, Molecular Biology, Pharmacology, Surgery, and Pulmonary and Respiratory Medicine.

The scientist's main research topics include:

  • Polysaccharides and Plant Cell Walls
  • Kawasaki Disease and Coronary Complications
  • Fungal Biology and Applications
  • Microbial Metabolites in Food Biotechnology
  • Coronary Artery Anomalies
  • Antifungal resistance and susceptibility
  • Studies on Chitinases and Chitosanases

Naohito Ohno has published extensively in various scientific journals. Frequent publication venues include:

  • International journal of medicinal mushrooms
  • Biological and Pharmaceutical Bulletin
  • Carbohydrate Research
  • International Journal of Molecular Sciences
  • Nature Communications

Recent notable papers by Ohno and colleagues include:

  • "Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding protein expression" (2023, Nature Communications)
  • "Biological Activity of High-Purity β-1,3-1,6-Glucan Derived from the Black Yeast Aureobasidium pullulans: A Literature Review" (2021, Nutrients)
  • "CDCP1 on Dendritic Cells Contributes to the Development of a Model of Kawasaki Disease" (2021, The Journal of Immunology)
  • "Development of a novel β-1,6-glucan-specific detection system using functionally-modified recombinant endo-β-1,6-glucanase" (2020, Journal of Biological Chemistry)
  • "Latent 1,3-β-D-glucan acts as an adjuvant for allergen-specific IgE production induced by Japanese cedar pollen exposure" (2020, Allergology International)

Among frequent co-authors, Naohito Ohno has collaborated with:

  • Yoshiyuki Adachi
  • Daisuke Yamanaka
  • Kenichi Ishibashi
  • Akitomo Motoi
  • Noriko N. Miura

Best Publications

  • Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans.

    Shinobu Saijo;Noriyuki Fujikado;Takahisa Furuta;Soo Hyun Chung

  • Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

    Shinobu Saijo;Satoshi Ikeda;Keiko Yamabe;Shigeru Kakuta

  • The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors.

    Hiromitsu Hara;Chitose Ishihara;Arata Takeuchi;Takayuki Imanishi

  • Saccharomyces cerevisiae- and Candida albicans-Derived Mannan Induced Production of Tumor Necrosis Factor Alpha by Human Monocytes in a CD14- and Toll-Like Receptor 4-Dependent Manner

    Hiroyuki Tada;Eiji Nemoto;Hidetoshi Shimauchi;Toshihiko Watanabe

  • Inhibition of Dectin-1 Signaling Ameliorates Colitis by Inducing Lactobacillus-Mediated Regulatory T Cell Expansion in the Intestine

    Ce Tang;Ce Tang;Tomonori Kamiya;Yang Liu;Yang Liu;Motohiko Kadoki;Motohiko Kadoki

  • Characterization of β-Glucan Recognition Site on C-Type Lectin, Dectin 1

    Yoshiyuki Adachi;Takashi Ishii;Yoshihiko Ikeda;Akiyoshi Hoshino

  • Antitumor β-Glucan from the Cultured Fruit Body of Agaricus blazei

    Naohito Ohno;Mai Furukawa;Noriko N. Miura;Yoshiyuki Adachi

  • Enhancement of Cytokine Production by Macrophages Stimulated with (1→3)-β-D-Glucan, Grifolan (GRN), Isolated from Grifola frondosa

    Yoshiyuki Adachi;Mitsuhiro Okazaki;Naohito Ohno;Toshiro Yadomae

  • Antitumor 1,3-β-Glucan from Cultured Fruit Body of Sparassis crispa

    Naohito Ohno;Noriko N. Miura;Mitsuhiro Nakajima;Toshiro Yadomae

  • Structure-Activity Relationship of (1→3)-β-D-Glucans in the Induction of Cytokine Production from Macrophages, in Vitro

    Mitsuhiro Okazaki;Yoshiyuki Adachi;Naohito Ohno;Toshiro Yadomae

  • SOLUBILIZATION OF YEAST CELL-WALL BETA -(1 3)-D-GLUCAN BY SODIUM HYPOCHLORITE OXIDATION AND DIMETHYL SULFOXIDE EXTRACTION

    Naohito Ohno;Michiharu Uchiyama;Aiko Tsuzuki;Kazuhiro Tokunaka

  • The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory

    Keisuke Yoshida;Toshio Maekawa;Yujuan Zhu;Claire Renard-Guillet

  • Immunomodulation by orally administered β-glucan in mice

    Iwao Suzuki;Koichi Hashimoto;Naohito Ohno;Hideki Tanaka

  • MPO-ANCA induces IL-17 production by activated neutrophils in vitro via classical complement pathway-dependent manner

    Akiyoshi Hoshino;Tomokazu Nagao;Tomokazu Nagao;Noriko Nagi-Miura;Naohito Ohno

  • Immunopharmacological and immunotoxicological activities of a water-soluble (1→3)-β-d-glucan, CSBG from Candida spp.

    Kazuhiro Tokunaka;Naohito Ohno;Yoshiyuki Adachi;Shigenori Tanaka

  • Deoxynucleic Acids from Cryptococcus neoformans Activate Myeloid Dendritic Cells via a TLR9-Dependent Pathway

    Kiwamu Nakamura;Akiko Miyazato;Gang Xiao;Masumitsu Hatta

  • Toll-Like Receptor 9-Dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids from Candida albicans

    Akiko Miyazato;Akiko Miyazato;Kiwamu Nakamura;Natsuo Yamamoto;Héctor M. Mora-Montes

  • Comparison of the Immunopharmacological Activities of Triple and Single-Helical Schizophyllan in Mice

    Naohito Ohno;Noriko N. Miura;Norihisa Chiba;Yoshiyuki Adachi

  • Dectin-1 is not required for the host defense to Cryptococcus neoformans.

    Kiwamu Nakamura;Kiwamu Nakamura;Takeshi Kinjo;Shinobu Saijo;Akiko Miyazato

  • Induction of human neutrophil chemotaxis by Candida albicans-derived β-1,6-long glycoside side-chain-branched β-glucan

    Tadashi Sato;Kazuhisa Iwabuchi;Isao Nagaoka;Yoshiyuki Adachi

  • NMR characterization of the structure of a β-(1→3)-d-glucan isolate from cultured fruit bodies of Sparassis crispa

    Rui Tada;Toshie Harada;Noriko Nagi-Miura;Yoshiyuki Adachi

  • Immunopharmacological Characterization of a Highly Branched Fungal (1→3)-β-D-Glucan, OL-2,Isolated from Omphalia lapidescens

    Naohito Ohno;Kazuo Saito;Jiro Nemoto;Shinya Kaneko

  • Effect of SCG, 1,3-β- D -Glucan from Sparassis crispa on the Hematopoietic Response in Cyclophosphamide Induced Leukopenic Mice

    Toshie Harada;Noriko Miura;Yoshiyuki Adachi;Mitsuhiro Nakajima

  • Limited contribution of Toll-like receptor 2 and 4 to the host response to a fungal infectious pathogen, Cryptococcus neoformans

    Kiwamu Nakamura;Kiwamu Nakamura;Kazuya Miyagi;Yoshinobu Koguchi;Yuki Kinjo

Frequent Co-Authors

Yoshiyuki Adachi
Yoshiyuki Adachi Tokyo University of Pharmacy and Life Sciences
Toshiro Yadomae
Toshiro Yadomae University of Tokyo
Kazuo Suzuki
Kazuo Suzuki Teikyo University
Yoichiro Iwakura
Yoichiro Iwakura Tokyo University of Science
Hiroshi Tamura
Hiroshi Tamura Juntendo University
Shinobu Saijo
Shinobu Saijo Chiba University
Shizuo Akira
Shizuo Akira Osaka University
Kenichi Ishibashi
Kenichi Ishibashi Meiji Pharmaceutical University
Yoshiki Yamaguchi
Yoshiki Yamaguchi Tohoku Medical and Pharmaceutical University
Kiyoshi Takeda
Kiyoshi Takeda Osaka University

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