Xin Lin

Overview

Best Publications

• An improvement of the 2ˆ(-delta delta CT) method for quantitative real-time polymerase chain reaction data analysis.

  Xiayu Rao;Xuelin Huang;Zhicheng Zhou;Xin Lin

  1486
  Citations

• Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation.

  Mako Nakaya;Yichuan Xiao;Xiaofei Zhou;Jae Hoon Chang

  768
  Citations

• The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

  Wei Lei Yang;Jing Wang;Chia Hsin Chan;Szu Wei Lee;Szu Wei Lee

  657
  Citations

• The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens

  Yen Michael S. Hsu;Yongliang Zhang;Yun You;Donghai Wang

  495
  Citations

• A requirement for CARMA1 in TCR-induced NF-kappa B activation.

  Donghai Wang;Yun You;Sara M. Case;Linda M. McAllister-Lucas

  426
  Citations

• Phosphorylation of CARMA1 plays a critical role in T cell receptor-mediated NF-κB activation

  Reiko Matsumoto;Reiko Matsumoto;Donghai Wang;Marzenna Blonska;Hongxiu Li;Hongxiu Li

  381
  Citations

• Protein Kinase C-θ Participates in NF-κB Activation Induced by CD3-CD28 Costimulation through Selective Activation of IκB Kinase β

  Xin Lin;Alison O'Mahony;Yajun Mu;Romas Geleziunas

  379
  Citations

• Ubiquitination of RIP Is Required for Tumor Necrosis Factor α-induced NF-κB Activation

  Hongxiu Li;Masayuki Kobayashi;Marzenna Blonska;Yun You

  369
  Citations

• C-type lectin receptors Dectin-3 and Dectin-2 form a heterodimeric pattern-recognition receptor for host defense against fungal infection.

  Le Le Zhu;Xue Qiang Zhao;Changying Jiang;Yun You

  333
  Citations

• Human T-Cell Leukemia Virus Type 1 Tax Induction of NF-κB Involves Activation of the IκB Kinase α (IKKα) and IKKβ Cellular Kinases

  Romas Geleziunas;Sharon Ferrell;Xin Lin;Yajun Mu

  324
  Citations

• Constitutively Active Type I Insulin-Like Growth Factor Receptor Causes Transformation and Xenograft Growth of Immortalized Mammary Epithelial Cells and Is Accompanied by an Epithelial-to-Mesenchymal Transition Mediated by NF-κB and Snail

  Hyun Jung Kim;Beate C. Litzenburger;Xiaojiang Cui;David A. Delgado

  318
  Citations

• The 90-kDa Ribosomal S6 Kinase (pp90rsk) Phosphorylates the N-terminal Regulatory Domain of IκBα and Stimulates Its Degradation in Vitro

  Lucy Ghoda;Xin Lin;Warner C. Greene

  301
  Citations

• The Proto-Oncogene Cot Kinase Participates in CD3/CD28 Induction of NF-κB Acting through the NF-κB-Inducing Kinase and IκB Kinases

  Xin Lin;Emmett T Cunningham;Yajun Mu;Romas Geleziunas

  299
  Citations

• CD3/CD28 Costimulation-Induced NF-κB Activation Is Mediated by Recruitment of Protein Kinase C-θ, Bcl10, and IκB Kinase β to the Immunological Synapse through CARMA1

  Donghai Wang;Reiko Matsumoto;Yun You;Tuanjie Che

  294
  Citations

• IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion.

  Li Chuan Chan;Chia Wei Li;Weiya Xia;Jung Mao Hsu

  288
  Citations

• Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma.

  D G Jackson-Bernitsas;H Ichikawa;Y Takada;J N Myers

  268
  Citations

• Differential use of CARD9 by dectin-1 in macrophages and dendritic cells.

  Helen S. Goodridge;Takahiro Shimada;Andrea J. Wolf;Yen Michael S. Hsu

  257
  Citations

• NF-κB signaling pathways regulated by CARMA family of scaffold proteins

  Marzenna Blonska;Xin Lin

  240
  Citations

• Molecular Determinants of NF-κB-Inducing Kinase Action

  Xin Lin;Yajun Mu;Emmett T. Cunningham;Kenneth B. Marcu

  221
  Citations

• TAK1 Is Recruited to the Tumor Necrosis Factor-α (TNF-α) Receptor 1 Complex in a Receptor-interacting Protein (RIP)-dependent Manner and Cooperates with MEKK3 Leading to NF-κB Activation

  Marzenna Blonska;Prashant B. Shambharkar;Masayuki Kobayashi;Dongyu Zhang

  184
  Citations