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D-Index & Metrics

Microbiology

D-Index
66
Citations
13302
World Ranking
2434
National Ranking
985

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Bruce S. Klein is affiliated with the University of Wisconsin-Madison in the United States. Their research centers primarily on medicine, with a particular focus on immunology and microbiology. Klein has contributed extensively to the understanding of infectious diseases, epidemiology, and immunology, emphasizing fungal infections and antifungal resistance.

Klein's frequent research topics include:

  • Antifungal resistance and susceptibility
  • Fungal infections and studies
  • Asthma and respiratory diseases
  • Infectious diseases and mycology
  • T-cell and B-cell immunology
  • Plant pathogens and fungal diseases
  • Immune responses and vaccinations

Their notable recent publications cover a range of subjects related to fungal threats and immune responses. Selected papers include:

  • "Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture," 2020, published in mBio
  • "Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation," 2020, Cell Host & Microbe
  • "The Future of Fungi: Threats and Opportunities," 2022, G3 Genes Genomes Genetics
  • "Fungal Impacts on Earth's Ecosystems," 2025, Nature
  • "Focus on Fungi," 2024, Cell

Klein collaborates frequently with a core group of researchers, including:

  • Lucas dos Santos Dias
  • Marcel Wüthrich
  • Hannah E. Dobson
  • Jatin M. Vyas
  • Cleison Ledesma Taira

Their work is regularly published in several scientific venues, with the highest number of publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio
  • The Journal of Immunology
  • Journal of Fungi
  • Cell Host & Microbe

Bruce S. Klein's research spans several subfields, including infectious diseases, epidemiology, immunology, physiology, and plant science, reflecting a multidisciplinary approach to medical and biological research.

Among the recognitions Klein has received is election as a Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture.

    Matthew C. Fisher;Sarah J. Gurr;Christina A. Cuomo;David S. Blehert

  • Recognition by human V gamma 9/V delta 2 T cells of a GroEL homolog on Daudi Burkitt's lymphoma cells

    Paul Fisch;Miroslav Malkovsky;Susan Kovats;Els Sturm

  • Isolation of Blastomyces dermatitidis in soil associated with a large outbreak of blastomycosis in Wisconsin.

    Klein Bs;Vergeront Jm;Weeks Rj;Kumar Un

  • Global Control of Dimorphism and Virulence in Fungi

    Julie C. Nemecek;Marcel Wüthrich;Bruce S. Klein

  • Pulmonary neuroendocrine cells amplify allergic asthma responses

    Pengfei Sui;Pengfei Sui;Darin L. Wiesner;Jinhao Xu;Jinhao Xu;Yan Zhang;Yan Zhang

  • Virulence factors of medically important fungi.

    L H Hogan;B S Klein;S M Levitz

  • Dimorphism and virulence in fungi

    Bruce S. Klein;Brad Tebbets

  • Advances in combating fungal diseases: vaccines on the threshold

    Jim E. Cutler;George S. Deepe;Bruce S. Klein

  • Adaptive Immunity to Fungi

    Marcel Wüthrich;George S. Deepe;Bruce Klein

  • Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice

    Marcel Wüthrich;Benjamin Gern;Chiung Yu Hung;Karen Ersland

  • Vaccine Immunity to Pathogenic Fungi Overcomes the Requirement for CD4 Help in Exogenous Antigen Presentation to CD8+ T Cells Implications for Vaccine Development in Immune-deficient Hosts

    Marcel Wüthrich;Hanna I. Filutowicz;Tom Warner;George S. Deepe

  • Reduction of nosocomial infection during pediatric intensive care by protective isolation.

    Bruce S. Klein;William H. Perloff;Dennis G. Maki

  • Two outbreaks of blastomycosis along rivers in Wisconsin. Isolation of Blastomyces dermatitidis from riverbank soil and evidence of its transmission along waterways.

    Bruce S. Klein;James M. Vergeront;Arthur F. Disalvo;Leo Kaufman

  • Targeted gene disruption reveals an adhesin indispensable for pathogenicity of Blastomyces dermatitidis.

    T. Tristan Brandhorst;Marcel Wüthrich;Thomas Warner;Bruce Klein

  • Clinical Manifestations and Treatment of Blastomycosis.

    Joseph A. McBride;Gregory M. Gauthier;Bruce S. Klein

  • T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity.

    Ryan W. Nelson;Daniel Beisang;Noah J. Tubo;Thamotharampillai Dileepan

  • Altered expression of surface alpha-1,3-glucan in genetically related strains of Blastomyces dermatitidis that differ in virulence.

    L H Hogan;B S Klein

  • Linking fungal morphogenesis with virulence.

    Peggy J. Rooney;Bruce S. Klein

  • The WI-1 antigen of Blastomyces dermatitidis yeasts mediates binding to human macrophage CD11b/CD18 (CR3) and CD14.

    S. L. Newman;Sudha Chaturvedi;B. S. Klein

  • The role of respiratory syncytial virus and other viral pathogens in acute otitis media

    Bruce S. Klein;Fe Reyes Dollete;Robert H. Yolken

  • Adaptive Immunity to Fungi

    Akash Verma;Marcel Wüthrich;George Deepe;Bruce Klein

Frequent Co-Authors

George S. Deepe
George S. Deepe University of Cincinnati
Jeffrey P. Davis
Jeffrey P. Davis Children's Hospital of Wisconsin
Garry T. Cole
Garry T. Cole The University of Texas at San Antonio
Christina A. Cuomo
Christina A. Cuomo Broad Institute
Jeniel E. Nett
Jeniel E. Nett University of Wisconsin–Madison
Leo Kaufman
Leo Kaufman Centers for Disease Control and Prevention
William E. Goldman
William E. Goldman University of North Carolina at Chapel Hill
Arturo Casadevall
Arturo Casadevall Johns Hopkins University
Stuart M. Levitz
Stuart M. Levitz University of Massachusetts Chan Medical School
David R. Andes
David R. Andes University of Wisconsin–Madison

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