World's Best Scientists 2026 revealed!
John R. Perfect

John R. Perfect

Award Badge
Microbiology
USA
2026

D-Index & Metrics

Microbiology

D-Index
147
Citations
81886
World Ranking
40
National Ranking
21

Medicine

D-Index
147
Citations
82489
World Ranking
1279
National Ranking
741

Research.com Recognitions

  • 2026 - Research.com Microbiology in United States Leader Award
  • 2025 - Research.com Microbiology in United States Leader Award
  • 2022 - Research.com Microbiology in United States Leader Award
  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

John R. Perfect is affiliated with Duke University in the United States. Their research primarily focuses on Medicine, with a strong emphasis on subfields such as Epidemiology and Infectious Diseases. Additional areas of study include Plant Science, Molecular Biology, and Cell Biology.

Their work extensively covers topics related to fungal infections and antimicrobial resistance, reflecting the following main topics:

  • Antifungal resistance and susceptibility
  • Fungal Infections and Studies
  • Nail Diseases and Treatments
  • Plant Pathogens and Fungal Diseases
  • Infectious Diseases and Mycology
  • Antimicrobial Resistance in Staphylococcus
  • Yeasts and Rust Fungi Studies

Notable recent papers authored or co-authored by John R. Perfect include:

  • Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance, 2020, The Lancet Infectious Diseases
  • ECMM/ISHAM recommendations for clinical management of COVID-19 associated mucormycosis in low- and middle-income countries, 2021, Mycoses
  • Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM, 2021, The Lancet Infectious Diseases
  • Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM, 2024, The Lancet Infectious Diseases
  • Core Recommendations for Antifungal Stewardship: A Statement of the Mycoses Study Group Education and Research Consortium, 2020, The Journal of Infectious Diseases

John R. Perfect regularly publishes in several key journals, with multiple contributions in the following venues:

  • Clinical Infectious Diseases
  • Medical Mycology
  • The Lancet Infectious Diseases
  • mBio
  • American Journal of Transplantation

Frequent collaborators in their research include Oliver A. Cornely, Martin Hoenigl, Luis Ostrosky-Zeichner, Peter G. Pappas, and Arunaloke Chakrabarti.

The scientist has been recognized within the professional community, receiving awards such as:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2007
  • Member of the Association of American Physicians

Best Publications

  • Revised Definitions of Invasive Fungal Disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group

    Ben De Pauw;Thomas J. Walsh;J. Peter Donnelly;David A. Stevens

  • Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america.

    John R. Perfect;William E. Dismukes;Francoise Dromer;David L. Goldman

  • Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium

    J. Peter Donnelly;Sharon C. Chen;Carol A. Kauffman;William J. Steinbach

  • Posaconazole vs. Fluconazole or Itraconazole Prophylaxis in Patients with Neutropenia

    Oliver A. Cornely;Johan Maertens;Drew J. Winston;John Perfect

  • Comparison of caspofungin and amphotericin B for invasive candidiasis.

    Jorge Mora-Duarte;Robert Betts;Coleman Rotstein;Arnaldo Lopes Colombo

  • Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans.

    T G Mitchell;J R Perfect

  • Practice Guidelines for the Management of Cryptococcal Disease

    Michael S. Saag;Richard J. Graybill;Robert A. Larsen;Peter G. Pappas

  • Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever

    Thomas J. Walsh;Peter Pappas;Drew J. Winston;Hillard M. Lazarus

  • The antifungal pipeline: a reality check

    John R. Perfect

  • Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance.

    Philipp Koehler;Matteo Bassetti;Arunaloke Chakrabarti;Sharon C.A. Chen;Sharon C.A. Chen

  • Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: An externally controlled trial

    Thomas J. Walsh;Issam Raad;Thomas F. Patterson;Pranatharthi Chandrasekar

  • Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

    Bart Ferwerda;Gerben Ferwerda;Theo S. Plantinga;Janet A. Willment

  • An Official American Thoracic Society Statement: Treatment of Fungal Infections in Adult Pulmonary and Critical Care Patients

    Andrew H. Limper;Kenneth S. Knox;George A. Sarosi;Neil M. Ampel

  • Resistance to Antifungal Agents: Mechanisms and Clinical Impact

    Zeina A. Kanafani;John R. Perfect

  • Voriconazole Treatment for Less-Common, Emerging, or Refractory Fungal Infections

    John R. Perfect;Kieren A. Marr;Thomas J. Walsh;Richard N. Greenberg

  • Cryptococcosis in Human Immunodeficiency Virus-Negative Patients in the Era of Effective Azole Therapy

    Peter G. Pappas;John R. Perfect;Gretchen A. Cloud;Robert A. Larsen

  • Amphotericin B Lipid Complex for Invasive Fungal Infections: Analysis of Safety and Efficacy in 556 Cases

    Thomas J. Walsh;John W. Hiemenz;Nita L. Seibel;John R. Perfect

  • Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA.

    D L Toffaletti;T H Rude;S A Johnston;D T Durack

  • Isavuconazole Treatment for Mucormycosis: A Single-Arm Open-Label Trial and Case-Control Analysis

    Francisco M. Marty;Luis Ostrosky-Zeichner;Oliver A. Cornely;Kathleen M. Mullane

  • Combination Antifungal Therapy

    Melissa D. Johnson;Conan MacDougall;Luis Ostrosky-Zeichner;John R. Perfect

Frequent Co-Authors

Joseph Heitman
Joseph Heitman Duke University
Wiley A. Schell
Wiley A. Schell Duke University
Gary M. Cox
Gary M. Cox Duke University
Barbara D. Alexander
Barbara D. Alexander Duke University
William J. Steinbach
William J. Steinbach Duke University
Thomas J. Walsh
Thomas J. Walsh Weill Cornell Medicine
Peter G. Pappas
Peter G. Pappas University of Alabama at Birmingham
Arturo Casadevall
Arturo Casadevall Johns Hopkins University
Christina A. Cuomo
Christina A. Cuomo Broad Institute
Oliver A. Cornely
Oliver A. Cornely University of Cologne

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