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Biology and Biochemistry

D-Index
84
Citations
22405
World Ranking
3372
National Ranking
1696

Research.com Recognitions

  • 2020 - National Institutes of Health Director's Pioneer Award
  • 2017 - Polish Academy of Science
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Magdalena Zernicka-Goetz is affiliated with the California Institute of Technology in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with significant contributions to medicine. The main areas of study include molecular biology, public health, environmental and occupational health, cell biology, biomedical engineering, and immunology.

The scientist's work focuses on various topics within biomedical research, notably pluripotent stem cells research, reproductive biology and fertility, CRISPR and genetic engineering, single-cell and spatial transcriptomics, renal and related cancers, 3D printing in biomedical research, and reproductive system and pregnancy.

Magdalena Zernicka-Goetz has frequently published in a range of scientific venues. Notable publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature Cell Biology
  • Nature
  • eLife

The scientist has collaborated often with colleagues including Bailey A. T. Weatherbee, Meng Zhu, Gianluca Amadei, Carlos W. Gantner, and Marta N. Shahbazi.

Recent papers by Magdalena Zernicka-Goetz include:

  • "PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications" (2021, Nature Cell Biology)
  • "Embryo model completes gastrulation to neurulation and organogenesis" (2022, Nature)
  • "Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids" (2021, eLife)
  • "Pluripotent stem cell-derived model of the post-implantation human embryo" (2023, Nature)
  • "Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism" (2020, Nature Communications)

The scientist has received several awards including the National Institutes of Health Director's Pioneer Award in 2020 and recognition from the Polish Academy of Science in 2017. Magdalena Zernicka-Goetz is also a member of the European Molecular Biology Organization (EMBO) and a fellow of The Academy of Medical Sciences, United Kingdom.

Best Publications

  • Specific interference with gene function by double-stranded RNA in early mouse development

    Florence Wianny;Magdalena Zernicka-Goetz

  • G&T-seq: parallel sequencing of single-cell genomes and transcriptomes

    Iain C Macaulay;Wilfried Haerty;Parveen Kumar;Yang I Li;Yang I Li

  • Self-organization of the in vitro attached human embryo

    Alessia Deglincerti;Gist F. Croft;Lauren N. Pietila;Magdalena Zernicka-Goetz

  • Self-organization of the human embryo in the absence of maternal tissues

    Marta N. Shahbazi;Agnieszka Jedrusik;Sanna Vuoristo;Gaelle Recher;Gaelle Recher

  • A Genome-Wide Study of Gene Activity Reveals Developmental Signaling Pathways in the Preimplantation Mouse Embryo

    Q.Tian Wang;Karolina Piotrowska;Maria Anna Ciemerych;Ljiljana Milenkovic

  • Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos

    Mubeen Goolam;Antonio Scialdone;Antonio Scialdone;Sarah J.L. Graham;Iain C. Macaulay

  • Self-Organizing Properties of Mouse Pluripotent Cells Initiate Morphogenesis upon Implantation

    Ivan Bedzhov;Ivan Bedzhov;Magdalena Zernicka-Goetz;Magdalena Zernicka-Goetz

  • Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential

    Helen Bolton;Sarah J. L. Graham;Niels Van der Aa;Parveen Kumar

  • Citrullination regulates pluripotency and histone H1 binding to chromatin

    Maria A Christophorou;Gonçalo Castelo-Branco;Richard P Halley-Stott;Clara Slade Oliveira

  • Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro

    Sarah Ellys Harrison;Berna Sozen;Berna Sozen;Neophytos Christodoulou;Christos Kyprianou

  • Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo

    Magdalena Zernicka-Goetz;Samantha A. Morris;Alexander W. Bruce

  • Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo

    Samantha A. Morris;Roy T. Y. Teo;Huiliang Li;Paul Robson

  • Role for sperm in spatial patterning of the early mouse embryo

    Karolina Piotrowska;Magdalena Zernicka-Goetz

  • Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo

    Berenika Plusa;Stephen Frankenberg;Andrew Chalmers;Andrew Chalmers;Anna Katerina Hadjantonakis

  • Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures

    Berna Sozen;Berna Sozen;Gianluca Amadei;Andy Cox;Ran Wang

  • Role of Cdx2 and cell polarity in cell allocation and specification of trophectoderm and inner cell mass in the mouse embryo

    Agnieszka Jedrusik;David-Emlyn Parfitt;Guoji Guo;Maria Skamagki

  • Dynamic distribution of the replacement histone variant H3.3 in the mouse oocyte and preimplantation embryos.

    Maria-Elena Torres-Padilla;Andrew J. Bannister;Paul J. Hurd;Tony Kouzarides

  • Four-cell stage mouse blastomeres have different developmental properties

    Karolina Piotrowska-Nitsche;Aitana Perea-Gomez;Aitana Perea-Gomez;Seiki Haraguchi;Seiki Haraguchi;Magdalena Zernicka-Goetz

  • Blastomeres arising from the first cleavage division have distinguishable fates in normal mouse development.

    Karolina Piotrowska;Florence Wianny;Roger A. Pedersen;Roger A. Pedersen;Magdalena Zernicka-Goetz

  • Self-Assembly of Embryonic and Two Extraembryonic Stem Cell Types Into Gastrulating Embryo-like Structures

    Berna Sozen;Gianluca Amadei;Andy Cox;Ran Wang

Frequent Co-Authors

David M. Glover
David M. Glover California Institute of Technology
Thierry Voet
Thierry Voet KU Leuven
John C. Marioni
John C. Marioni European Bioinformatics Institute
Jonathon Pines
Jonathon Pines Institute of Cancer Research
Anna-Katerina Hadjantonakis
Anna-Katerina Hadjantonakis Memorial Sloan Kettering Cancer Center
Bernard Maro
Bernard Maro Tel Aviv University
Paul Robson
Paul Robson University of Connecticut
Wolf Reik
Wolf Reik Babraham Institute
Virginia E. Papaioannou
Virginia E. Papaioannou Columbia University Medical Center
Eric A. Miska
Eric A. Miska University of Cambridge

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