D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 65 Citations 14,565 152 World Ranking 1844 National Ranking 50

Research.com Recognitions

Awards & Achievements

2011 - Fellow of the Royal Society, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

His scientific interests lie mostly in Cell biology, Anatomy, Gastrulation, Epiblast and Genetics. His Cell biology research is multidisciplinary, incorporating perspectives in Embryonic stem cell, Endoderm and Cellular differentiation. The study incorporates disciplines such as Lineage and Lineage markers in addition to Embryonic stem cell.

His Cellular differentiation research includes elements of Molecular biology, Stem cell and Germ cell. His work deals with themes such as Paraxial mesoderm, Lateral plate mesoderm, Mesoderm, Hindbrain and Germ layer, which intersect with Anatomy. As a part of the same scientific study, Patrick P.L. Tam usually deals with the Gastrulation, concentrating on Transplantation and frequently concerns with Bone marrow, Integrin, Biochemistry and Haematopoiesis.

His most cited work include:

  • Depletion of definitive gut endoderm in Sox17-null mutant mice. (595 citations)
  • SOX9 Binds DNA, Activates Transcription, and Coexpresses with Type II Collagen during Chondrogenesis in the Mouse (576 citations)
  • Mouse gastrulation: the formation of a mammalian body plan (461 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cell biology, Genetics, Embryonic stem cell, Embryo and Gastrulation. His Cell biology research is multidisciplinary, incorporating elements of Germ layer, Endoderm, Anatomy and Mesoderm. His study in the field of Definitive endoderm also crosses realms of Histogenesis.

His research investigates the link between Embryonic stem cell and topics such as Stem cell that cross with problems in Induced pluripotent stem cell. His studies in Gastrulation integrate themes in fields like Morphogenesis, Wnt signaling pathway and Organogenesis. His research in Epiblast intersects with topics in Ectoderm and Germ line development.

He most often published in these fields:

  • Cell biology (81.82%)
  • Genetics (27.92%)
  • Embryonic stem cell (29.87%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cell biology (81.82%)
  • Computational biology (10.39%)
  • Gene (19.16%)

In recent papers he was focusing on the following fields of study:

Patrick P.L. Tam mainly investigates Cell biology, Computational biology, Gene, Embryonic stem cell and Cell type. His research integrates issues of Germ layer and Endoderm in his study of Cell biology. His Computational biology study also includes

  • Cell which intersects with area such as Cell identity, Gene expression and Somatic cell,
  • Chromatin, which have a strong connection to Developmental biology, Ectomesenchyme, Neural crest cell differentiation and Neural stem cell.

Patrick P.L. Tam has included themes like Regulation of gene expression, Transcription factor and Stem cell in his Embryonic stem cell study. His work in Cell type covers topics such as Induced pluripotent stem cell which are related to areas like Stromal cell, Niche and Cellular differentiation. His work in Epiblast addresses issues such as Ectoderm, which are connected to fields such as DKK1 and Neuroectoderm.

Between 2018 and 2021, his most popular works were:

  • Establishment of porcine and human expanded potential stem cells (98 citations)
  • Molecular architecture of lineage allocation and tissue organization in early mouse embryo (49 citations)
  • Molecular architecture of lineage allocation and tissue organization in early mouse embryo (49 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genetics

Patrick P.L. Tam mostly deals with Cell biology, Epiblast, Germ layer, Computational biology and Transcriptome. His Cell biology research is multidisciplinary, relying on both Zebrafish, NODAL and Motile cilium. The Epiblast study combines topics in areas such as Ectoderm and Endoderm.

His Endoderm study incorporates themes from Inner cell mass, Embryonic Programming and Embryo. His study looks at the relationship between Germ layer and fields such as Cellular differentiation, as well as how they intersect with chemical problems. His study in Transcriptome is interdisciplinary in nature, drawing from both Cell and Developmental cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

SOX9 Binds DNA, Activates Transcription, and Coexpresses with Type II Collagen during Chondrogenesis in the Mouse

Ling-Jim Ng;Susan Wheatley;George E.O Muscat;John Conway-Campbell.
Developmental Biology (1997)

745 Citations

Depletion of definitive gut endoderm in Sox17-null mutant mice.

Masami Kanai-Azuma;Yoshiakira Kanai;Jacqueline M. Gad;Youichi Tajima.
Development (2002)

737 Citations

Gene function in mouse embryogenesis: get set for gastrulation.

Patrick P. L. Tam;David A. F. Loebel.
Nature Reviews Genetics (2007)

696 Citations

Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse.

Janet Rossant;Patrick P. L. Tam.
Development (2009)

674 Citations

Mouse gastrulation: the formation of a mammalian body plan

Patrick P.L Tam;Richard R Behringer.
Mechanisms of Development (1997)

616 Citations

The allocation of epiblast cells to ectodermal and germ-line lineages is influenced by the position of the cells in the gastrulating mouse embryo.

Patrick P.L. Tam;Sheila X. Zhou.
Developmental Biology (1996)

504 Citations

Mutations of CDKL5 Cause a Severe Neurodevelopmental Disorder with Infantile Spasms and Mental Retardation

Linda S. Weaving;Linda S. Weaving;John Christodoulou;John Christodoulou;Sarah L. Williamson;Sarah L. Williamson;Kathie L. Friend.
American Journal of Human Genetics (2004)

432 Citations

Cranial paraxial mesoderm and neural crest cells of the mouse embryo: co-distribution in the craniofacial mesenchyme but distinct segregation in branchial arches.

Paul A. Trainor;Patrick P. L. Tam.
Development (1995)

426 Citations

The orderly allocation of mesodermal cells to the extraembryonic structures and the anteroposterior axis during gastrulation of the mouse embryo

Simon J. Kinder;Tania E. Tsang;Gabriel A. Quinlan;Anna Katerina Hadjantonakis.
Development (1999)

420 Citations

Extrinsic regulation of pluripotent stem cells

Martin F. Pera;Patrick P. L. Tam;Patrick P. L. Tam.
Nature (2010)

379 Citations

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