What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Genetics, Cell biology, Gene, X chromosome and Missense mutation.
Genetics is often connected to Epilepsy in his work.
His work carried out in the field of Cell biology brings together such families of science as Corticotropic cell, Cell type and Cellular differentiation.
His work on RNA-binding protein, Messenger RNA and Phenotype as part of his general Gene study is frequently connected to Nonsense-mediated decay, thereby bridging the divide between different branches of science.
His X chromosome research incorporates elements of Molecular biology, Cell nucleus, Zinc finger and Gene mutation.
His work in Mutation addresses subjects such as Bone morphogenetic protein 4, which are connected to disciplines such as Internal medicine and Endocrinology.
His most cited work include:
- Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse (636 citations)
- Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo (490 citations)
- Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors (473 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Genetics, Cell biology, Gene, Endocrinology and Internal medicine.
In most of his Genetics studies, his work intersects topics such as Epilepsy.
His study in Cell biology is interdisciplinary in nature, drawing from both Embryonic stem cell, Regulation of gene expression, Cellular differentiation and Anatomy.
Paul Q. Thomas works mostly in the field of Cellular differentiation, limiting it down to concerns involving Progenitor cell and, occasionally, Pituitary gland and Cell type.
The Anatomy study combines topics in areas such as Gastrulation and Endoderm.
His studies deal with areas such as Homing and Bioinformatics as well as Gene.
He most often published in these fields:
- Genetics (40.58%)
- Cell biology (34.78%)
- Gene (23.19%)
What were the highlights of his more recent work (between 2017-2021)?
- CRISPR (13.04%)
- Gene (23.19%)
- Genetics (40.58%)
In recent papers he was focusing on the following fields of study:
Paul Q. Thomas mainly focuses on CRISPR, Gene, Genetics, Gene drive and Allele.
His work on Cas9 and Genome editing as part of general CRISPR research is frequently linked to Synthetic gene, thereby connecting diverse disciplines of science.
He has researched Gene in several fields, including Precision medicine and Bioinformatics.
His research ties Epilepsy and Genetics together.
His work is dedicated to discovering how Disorders of sex development, Regulation of gene expression are connected with Testis determining factor and Mutation and other disciplines.
His Conditional gene knockout research focuses on Embryonic stem cell and how it relates to Cell biology.
Between 2017 and 2021, his most popular works were:
- Large deletions induced by Cas9 cleavage. (97 citations)
- Abnormal Cell Sorting Underlies the Unique X-Linked Inheritance of PCDH19 Epilepsy (45 citations)
- Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation (25 citations)
In his most recent research, the most cited papers focused on:
Paul Q. Thomas spends much of his time researching Gene drive, Allele, CRISPR, Genetics and Cas9.
His study explores the link between Allele and topics such as Computational biology that cross with problems in Human genetics and Mutagenesis.
His CRISPR study is related to the wider topic of Gene.
His Genetics study frequently links to adjacent areas such as Epilepsy.
His work deals with themes such as Cleavage, Transgene, Subgenomic mRNA, Stereochemistry and Genome editing, which intersect with Cas9.
His study looks at the relationship between Protocadherin and topics such as Mutation, which overlap with Cell biology.
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