World's Best Scientists 2026 revealed!
Juan Pedro Martinez-Barbera

Juan Pedro Martinez-Barbera

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
11715
World Ranking
14397
National Ranking
1131

Overview

Juan Pedro Martinez-Barbera is affiliated with University College London in the United Kingdom. Their research spans multiple fields within medicine and biochemistry, genetics, and molecular biology, with a notable focus on endocrinology, diabetes, metabolism, molecular biology, and genetics.

Their work covers a range of key topics, centered primarily on pituitary gland disorders and treatments, as well as glioma diagnosis and treatment. Additional research interests include cancer, hypoxia, metabolism, telomeres, telomerase, and senescence. Other specialized topics include retinoids in leukemia and cellular processes, ubiquitin and proteasome pathways, and ocular oncology and treatments.

Juan Pedro Martinez-Barbera has published extensively, contributing to scientific literature in several venues. The most frequent publication venues include:

  • Neuro-Oncology
  • Neuropathology and Applied Neurobiology
  • Endocrine Abstracts
  • Journal of the Endocrine Society
  • UNC Libraries

Among their recent publications are the following papers:

  • Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer, 2023, Cancer Cell
  • Galactose-modified duocarmycin prodrugs as senolytics, 2020, Aging Cell
  • Hypothalamic syndrome, 2022, Nature Reviews Disease Primers
  • Contemporary Biological Insights and Clinical Management of Craniopharyngioma, 2022, Endocrine Reviews
  • Cell senescence in neuropathology: A focus on neurodegeneration and tumours, 2020, Neuropathology and Applied Neurobiology

The scientist has collaborated frequently with several co-authors throughout their career. These include:

  • John Apps
  • Romain Guiho
  • Thomas S. Jacques
  • Jesús Gil
  • Todd C. Hankinson

Juan Pedro Martinez-Barbera's body of work demonstrates cross-disciplinary involvement, combining clinical and molecular approaches primarily in endocrinology and cancer research contexts. Their contributions have focused on elucidating mechanisms related to cellular senescence, molecular pathways in cancer, and disorders of the pituitary gland and brain tumors.

Best Publications

  • Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse

    Mehul T. Dattani;Juan-Pedro Martinez-Barbera;Paul Q. Thomas;Joshua M. Brickman

  • mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

    Nicolás Herranz;Suchira Gallage;Massimiliano Mellone;Torsten Wuestefeld

  • The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain

    Bjarke Abrahamsen;Jing Zhao;Curtis O. Asante;Cruz Miguel Cendan

  • Heterozygous mutations of OTX2 cause severe ocular malformations.

    Nicola K. Ragge;Nicola K. Ragge;Nicola K. Ragge;Alison G. Brown;Charlotte M. Poloschek;Birgit Lorenz

  • Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas.

    Roque Bort;Juan Pedro Martinez-Barbera;Rosa S. P. Beddington;Kenneth S. Zaret

  • Over- and underdosage of SOX3 is associated with infundibular hypoplasia and hypopituitarism

    Kathryn S. Woods;Maria Cundall;James Turton;Karine Rizotti

  • Sox2+ Stem/Progenitor Cells in the Adult Mouse Pituitary Support Organ Homeostasis and Have Tumor-Inducing Potential

    Cynthia Lilian Andoniadou;Danielle Matsushima;Seyedeh Neda Mousavy Gharavy;Massimo Signore

  • Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans

    Carles Gaston-Massuet;Cynthia Lilian Andoniadou;Massimo Signore;Sujatha A. Jayakody

  • In Vivo Genetic Ablation by Cre-Mediated Expression of Diphtheria Toxin Fragment A

    Anna Ivanova;Massimo Signore;Nadia Caro;Nicholas D.E. Greene

  • Cardiac glycosides are broad-spectrum senolytics

    A Guerrero;N Herranz;B Sun;Wagner

  • HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death

    Nieves Peltzer;Eva Rieser;Lucia Taraborrelli;Peter Draber

  • Loss-of-function mutations in IGSF1 cause an X-linked syndrome of central hypothyroidism and testicular enlargement

    Yu Sun;Beata Bak;Nadia Schoenmakers;A. S Paul Van Trotsenburg

  • Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target

    John R. Apps;John R. Apps;Gabriela Carreno;Jose Mario Gonzalez-Meljem;Scott Haston

  • SOX2 Plays a Critical Role in the Pituitary, Forebrain, and Eye during Human Embryonic Development

    Daniel Kelberman;Sandra C. P. de Castro;Shuwen Huang;John A. Crolla

  • Identification of novel pathways involved in the pathogenesis of human adamantinomatous craniopharyngioma.

    Cynthia L. Andoniadou;Carles Gaston-Massuet;Rukmini Reddy;Ralph P. Schneider

  • Paracrine roles of cellular senescence in promoting tumourigenesis.

    Jose Mario Gonzalez-Meljem;John Richard Apps;Helen Christina Fraser;Juan Pedro Martinez-Barbera

  • Defining the Integration Capacity of Embryonic Stem Cell-Derived Photoreceptor Precursors†‡§

    Emma L. West;Anai Gonzalez-Cordero;Claire Hippert;Fumitaka Osakada

  • Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2.

    Juan Pedro Martinez-Barbera;Massimo Signore;Pietro Pilo Boyl;Eduardo Puelles

  • The Homeobox Gene Hesx1 Is Required in the Anterior Neural Ectoderm for Normal Forebrain Formation

    Juan Pedro Martinez-Barbera;Tristan A Rodriguez;Rosa S.P Beddington

  • Novel FGF8 Mutations Associated with Recessive Holoprosencephaly, Craniofacial Defects, and Hypothalamo-Pituitary Dysfunction

    Mark J. McCabe;Carles Gaston-Massuet;Vaitsa Tziaferi;Louise C. Gregory

Frequent Co-Authors

Mehul T. Dattani
Mehul T. Dattani University College London
Jesús Gil
Jesús Gil Imperial College London
Antonio Simeone
Antonio Simeone King's College London
Dario Acampora
Dario Acampora King's College London
Hywel Williams
Hywel Williams University College London
Dominic J. Withers
Dominic J. Withers Imperial College London
Lars Zender
Lars Zender German Cancer Research Center
Paul Thomas
Paul Thomas University of Adelaide
Rosa S. P. Beddington
Rosa S. P. Beddington Medical Research Council
Stefan Krauss
Stefan Krauss University of Oslo

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