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Biology and Biochemistry

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86
Citations
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World Ranking
2992
National Ranking
222

Medicine

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86
Citations
24913
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14222
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Overview

Robin R. Ali is affiliated with King's College London in the United Kingdom and conducts research primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work focuses extensively on Molecular Biology and Ophthalmology, with additional studies spanning Cellular and Molecular Neuroscience, Radiology, Nuclear Medicine and Imaging, and Physiology.

The scientist's main research topics include Retinal Development and Disorders, Retinal Diseases and Treatments, and Photoreceptor and Optogenetics research. Other noted areas of interest are RNA regulation and disease, Cellular transport and secretion, CRISPR and Genetic Engineering, and Retinopathy of Prematurity Studies.

Robin R. Ali has contributed to a number of peer-reviewed publications over recent years. Significant recent papers include:

  • Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors, 2021, Cell Reports
  • Nanotube-like processes facilitate material transfer between photoreceptors, 2021, EMBO Reports
  • Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1 Disruption Using CRISPR-Cas9, 2020, Molecular Therapy
  • Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium, 2020, Translational Vision Science & Technology
  • Pou2f1 and Pou2f2 cooperate to control the timing of cone photoreceptor production in the developing mouse retina, 2020, Development

The researcher has also been involved in book publication, notably "Clinical Laboratory Diagnostics: Use and Assessment of Clinical Laboratory Results" published in 2024 by Bright Sky Publications eBooks.

Collaborations have been frequent with other researchers, including Alexander J. Smith, James Bainbridge, R. A. Pearson, Anastasios Georgiadis, and Michel Michaelides, reflecting a network of coauthors across multiple projects and studies.

Key venues where Robin R. Ali has published frequently include bioRxiv (Cold Spring Harbor Laboratory), Human Gene Therapy, Stem Cell Reports, Translational Vision Science & Technology, and Cells. These publication venues highlight a concentration on both preprint sharing and peer-reviewed journals centered around gene therapy, stem cell research, and vision science.

Best Publications

  • Effect of gene therapy on visual function in Leber's congenital amaurosis.

    James W B Bainbridge;Alexander J Smith;Susie S Barker;Scott Robbie

  • Retinal Repair by Transplantation of Photoreceptor Precursors

    R. E. MacLaren;R. A. Pearson;A. MacNeil;R. H. Douglas

  • Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

    H Bobby Gaspar;Kathryn L Parsley;Steven Howe;Doug King

  • Long-Term Effect of Gene Therapy on Leber’s Congenital Amaurosis

    James W B Bainbridge;James W B Bainbridge;Manjit S Mehat;Venki Sundaram;Scott J Robbie

  • Effective gene therapy with nonintegrating lentiviral vectors

    Rafael J Yáñez-Muñoz;Rafael J Yáñez-Muñoz;Rafael J Yáñez-Muñoz;Kamaljit S Balaggan;Angus MacNeil;Steven J Howe

  • Restoration of vision after transplantation of photoreceptors

    R. A. Pearson;A. C. Barber;M. Rizzi;C. Hippert

  • Retinal Ganglion Cell Apoptosis in Glaucoma Is Related to Intraocular Pressure and IOP-Induced Effects on Extracellular Matrix

    Li Guo;Stephen E. Moss;Robert A. Alexander;Robin R. Ali

  • Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina

    Anai Gonzalez-Cordero;Emma L West;Rachael A Pearson;Yanai Duran

  • Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy

    Robin R. Ali;Gian-Marco Sarra;Clare Stephens;Mahesh de Alwis

  • Gene Transfer into the Mouse Retina Mediated by an Adeno-Associated Viral Vector

    Robin R. Ali;Martin B. Reichel;Adrian J. Thrasher;Roland J. Levinsky

  • Repair of the degenerate retina by photoreceptor transplantation

    Amanda C. Barber;Claire Hippert;Yanai Duran;Emma L. West

  • Efficient and Selective AAV2-Mediated Gene Transfer Directed to Human Vascular Endothelial Cells

    Stuart A. Nicklin;Hildegard Buening;Kate L. Dishart;Mahesh de Alwis

  • Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors.

    R. A. Pearson;A. Gonzalez-Cordero;E. L. West;J. R. Ribeiro

  • Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector.

    S. L. Hart;C. V. Arancibia-Carcamo;M. A. Wolfert;C. Mailhos

  • The Drusenlike Phenotype in Aging Ccl2-Knockout Mice Is Caused by an Accelerated Accumulation of Swollen Autofluorescent Subretinal Macrophages

    Ulrich F O Luhmann;Scott Robbie;Peter M G Munro;Susie E Barker

  • Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA.

    Tony Sourisseau;Anastasios Georgiadis;Anna Tsapara;Robin R. Ali

  • Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors

    Anai Gonzalez-Cordero;Kamil Kruczek;Arifa Naeem;Milan Fernando

  • In vivo gene transfer to the mouse eye using an HIV-based lentiviral vector; efficient long-term transduction of corneal endothelium and retinal pigment epithelium.

    J. W. B. Bainbridge;C. Stephens;K. Parsley;C. Demaison

  • Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium

    G Le Meur;K Stieger;A J Smith;M Weber

  • Transplantation of human embryonic stem cell-derived retinal pigment epithelial cells in macular degeneration

    Manjit S Mehat;Venki Sundaram;Caterina Ripamonti;Anthony G Robson

Frequent Co-Authors

Jane C. Sowden
Jane C. Sowden University College London
Adrian J. Thrasher
Adrian J. Thrasher University College London
Andrew D. Dick
Andrew D. Dick University of Bristol
Shomi S. Bhattacharya
Shomi S. Bhattacharya University College London
David Hunt
David Hunt University of Edinburgh
Anthony T. Moore
Anthony T. Moore University of California, San Francisco
Andrew R. Webster
Andrew R. Webster University College London
Gary S. Rubin
Gary S. Rubin University College London
Sara E. Mole
Sara E. Mole University College London
Simon N. Waddington
Simon N. Waddington University College London

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