2015 - Fellow of the American Academy of Arts and Sciences
1988 - Fellow of the American Association for the Advancement of Science (AAAS)
Her primary areas of study are Retinal, Genetic enhancement, Retina, Cis-trans-Isomerases and RPE65. In her study, which falls under the umbrella issue of Retinal, Cone cell and Degenerative disease is strongly linked to Retinopathy. Her Genetic enhancement research is multidisciplinary, incorporating elements of Vector, Disease, Transduction and Neuroscience, Optic nerve.
Her Retina research includes elements of Genetics, Anatomy and Cell biology. Her Cis-trans-Isomerases investigation overlaps with other disciplines such as Ophthalmology and Visual acuity. Her RPE65 research includes themes of Leber's congenital amaurosis and Gene therapy of the human retina.
Her main research concerns Retinal, Genetic enhancement, Cell biology, Retina and Ophthalmology. She interconnects Retinopathy, Genetics and Disease in the investigation of issues within Retinal. Her Genetic enhancement study integrates concerns from other disciplines, such as Adeno-associated virus, Transgene, Bioinformatics, Viral vector and Neuroscience.
Her Retina study incorporates themes from Anatomy, Optic nerve and Pathology. Jean Bennett frequently studies issues relating to Clinical trial and Ophthalmology. Her RPE65 research incorporates themes from Leber's congenital amaurosis and Mutation.
Jean Bennett focuses on Retinal, RPE65, Ophthalmology, Genetic enhancement and Disease. Her work carried out in the field of Retinal brings together such families of science as Retina and Pathology. Her RPE65 research is multidisciplinary, relying on both Retinitis pigmentosa, Retinal dystrophy and Mutation.
Her Ophthalmology study frequently involves adjacent topics like Gene. Her Genetic enhancement study combines topics in areas such as Adeno-associated virus, Bioinformatics and Cell biology. Her biological study spans a wide range of topics, including Genetics and Oncology.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis
Albert M. Maguire;Francesca Simonelli;Eric A. Pierce;Edward N. Pugh.
The New England Journal of Medicine (2008)
Gene therapy restores vision in a canine model of childhood blindness.
Gregory M. Acland;Gustavo D. Aguirre;Jharna Ray;Qi Zhang.
Nature Genetics (2001)
Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial
Albert M. Maguire;Albert M. Maguire;Katherine A. High;Katherine A. High;Alberto Auricchio;J. Fraser Wright;J. Fraser Wright.
The Lancet (2009)
Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial
Stephen Russell;Jean Bennett;Jennifer A. Wellman;Daniel C. Chung.
The Lancet (2017)
Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.
Samuel J Reich;Joshua Fosnot;Akiko Kuroki;Waixing Tang.
Molecular Vision (2003)
Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.
Francesca Simonelli;Albert M Maguire;Albert M Maguire;Francesco Testa;Eric A Pierce.
Molecular Therapy (2010)
Lateral connectivity and contextual interactions in macaque primary visual cortex.
Dan D Stettler;Aniruddha Das;Jean Bennett;Charles D Gilbert.
Long-Term Restoration of Rod and Cone Vision by Single Dose rAAV-Mediated Gene Transfer to the Retina in a Canine Model of Childhood Blindness
Gregory M. Acland;Gustavo D. Aguirre;Jean Bennett;Tomas S. Aleman.
Molecular Therapy (2005)
Mutation of a nuclear receptor gene, NR2E3 , causes enhanced S cone syndrome, a disorder of retinal cell fate
Neena B. Haider;Samuel G. Jacobson;Artur V. Cideciyan;Ruth Swiderski.
Nature Genetics (2000)
The molecular basis of antibody formation: a paradox
W J Dreyer;J C Bennett.
Proceedings of the National Academy of Sciences of the United States of America (1965)
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