D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 71 Citations 18,286 229 World Ranking 2802 National Ranking 1463
Medicine D-index 74 Citations 23,122 242 World Ranking 12480 National Ranking 6616

Research.com Recognitions

Awards & Achievements

2015 - Fellow of the American Academy of Arts and Sciences

1988 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Enzyme

Her primary areas of study are Retinal, Genetic enhancement, Retina, Cis-trans-Isomerases and RPE65. In her study, which falls under the umbrella issue of Retinal, Cone cell and Degenerative disease is strongly linked to Retinopathy. Her Genetic enhancement research is multidisciplinary, incorporating elements of Vector, Disease, Transduction and Neuroscience, Optic nerve.

Her Retina research includes elements of Genetics, Anatomy and Cell biology. Her Cis-trans-Isomerases investigation overlaps with other disciplines such as Ophthalmology and Visual acuity. Her RPE65 research includes themes of Leber's congenital amaurosis and Gene therapy of the human retina.

Her most cited work include:

  • Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis (1779 citations)
  • Gene therapy restores vision in a canine model of childhood blindness. (1048 citations)
  • Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial (674 citations)

What are the main themes of her work throughout her whole career to date?

Her main research concerns Retinal, Genetic enhancement, Cell biology, Retina and Ophthalmology. She interconnects Retinopathy, Genetics and Disease in the investigation of issues within Retinal. Her Genetic enhancement study integrates concerns from other disciplines, such as Adeno-associated virus, Transgene, Bioinformatics, Viral vector and Neuroscience.

Her Retina study incorporates themes from Anatomy, Optic nerve and Pathology. Jean Bennett frequently studies issues relating to Clinical trial and Ophthalmology. Her RPE65 research incorporates themes from Leber's congenital amaurosis and Mutation.

She most often published in these fields:

  • Retinal (27.67%)
  • Genetic enhancement (28.30%)
  • Cell biology (21.80%)

What were the highlights of her more recent work (between 2017-2021)?

  • Retinal (27.67%)
  • RPE65 (18.03%)
  • Ophthalmology (21.38%)

In recent papers she was focusing on the following fields of study:

Jean Bennett focuses on Retinal, RPE65, Ophthalmology, Genetic enhancement and Disease. Her work carried out in the field of Retinal brings together such families of science as Retina and Pathology. Her RPE65 research is multidisciplinary, relying on both Retinitis pigmentosa, Retinal dystrophy and Mutation.

Her Ophthalmology study frequently involves adjacent topics like Gene. Her Genetic enhancement study combines topics in areas such as Adeno-associated virus, Bioinformatics and Cell biology. Her biological study spans a wide range of topics, including Genetics and Oncology.

Between 2017 and 2021, her most popular works were:

  • Efficacy, Safety, and Durability of Voretigene Neparvovec-rzyl in RPE65 Mutation-Associated Inherited Retinal Dystrophy: Results of Phase 1 and 3 Trials. (101 citations)
  • AAV2.7m8 is a powerful viral vector for inner ear gene therapy (58 citations)
  • Novel mobility test to assess functional vision in patients with inherited retinal dystrophies. (48 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

Albert M. Maguire;Francesca Simonelli;Eric A. Pierce;Edward N. Pugh.
The New England Journal of Medicine (2008)

2236 Citations

Gene therapy restores vision in a canine model of childhood blindness.

Gregory M. Acland;Gustavo D. Aguirre;Jharna Ray;Qi Zhang.
Nature Genetics (2001)

1389 Citations

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

Albert M. Maguire;Albert M. Maguire;Katherine A. High;Katherine A. High;Alberto Auricchio;J. Fraser Wright;J. Fraser Wright.
The Lancet (2009)

877 Citations

Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial

Stephen Russell;Jean Bennett;Jennifer A. Wellman;Daniel C. Chung.
The Lancet (2017)

733 Citations

Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.

Samuel J Reich;Joshua Fosnot;Akiko Kuroki;Waixing Tang.
Molecular Vision (2003)

688 Citations

Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.

Francesca Simonelli;Albert M Maguire;Albert M Maguire;Francesco Testa;Eric A Pierce.
Molecular Therapy (2010)

623 Citations

Lateral connectivity and contextual interactions in macaque primary visual cortex.

Dan D Stettler;Aniruddha Das;Jean Bennett;Charles D Gilbert.
Neuron (2002)

535 Citations

Long-Term Restoration of Rod and Cone Vision by Single Dose rAAV-Mediated Gene Transfer to the Retina in a Canine Model of Childhood Blindness

Gregory M. Acland;Gustavo D. Aguirre;Jean Bennett;Tomas S. Aleman.
Molecular Therapy (2005)

524 Citations

Mutation of a nuclear receptor gene, NR2E3 , causes enhanced S cone syndrome, a disorder of retinal cell fate

Neena B. Haider;Samuel G. Jacobson;Artur V. Cideciyan;Ruth Swiderski.
Nature Genetics (2000)

466 Citations

The molecular basis of antibody formation: a paradox

W J Dreyer;J C Bennett.
Proceedings of the National Academy of Sciences of the United States of America (1965)

458 Citations

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