His primary areas of investigation include Primary biliary cirrhosis, Immunology, Antibody, Autoantibody and Autoimmunity. Patrick S.C. Leung has researched Primary biliary cirrhosis in several fields, including Immunohistochemistry, Pathology, Autoimmune disease, Molecular biology and Epitope. His Immunology research includes themes of Liver disease and MEDLINE.
His studies in Antibody integrate themes in fields like Major histocompatibility complex, Pathogenesis and Pyruvate dehydrogenase complex. In his study, Primary sclerosing cholangitis is inextricably linked to Autoimmune hepatitis, which falls within the broad field of Autoantibody. His work deals with themes such as Natural killer T cell, Molecular mimicry, Antigen and Cell biology, which intersect with Autoimmunity.
Patrick S.C. Leung mostly deals with Immunology, Primary biliary cirrhosis, Antibody, Autoantibody and Autoimmunity. His Primary biliary cirrhosis study combines topics in areas such as Epitope, Biliary cirrhosis, Pyruvate dehydrogenase complex and Pathology. The study incorporates disciplines such as Molecular biology and Biochemistry in addition to Epitope.
His Antibody research incorporates elements of Intrahepatic bile ducts, Recombinant DNA and Pathogenesis. Patrick S.C. Leung studied Autoantibody and Autoimmune hepatitis that intersect with Primary sclerosing cholangitis. His work carried out in the field of Autoimmunity brings together such families of science as Molecular mimicry and Genetic predisposition.
His main research concerns Immunology, Autoimmunity, Immune system, Cancer research and Disease. His study in Immune tolerance, Allergy, Autoantibody, Immunoglobulin E and Antigen is carried out as part of his Immunology studies. His Autoantibody research incorporates themes from Genetic predisposition, Autoimmune disease, Escherichia coli, Immunopathology and Proinflammatory cytokine.
His work investigates the relationship between Escherichia coli and topics such as Xenobiotic that intersect with problems in Primary biliary cirrhosis. His research is interdisciplinary, bridging the disciplines of CD14 and Primary biliary cirrhosis. His Immune system study integrates concerns from other disciplines, such as Gut flora, Primary sclerosing cholangitis, Cholestasis and Pathogenesis.
Patrick S.C. Leung spends much of his time researching Immunology, Autoimmunity, Disease, Autoantibody and Molecular mimicry. Much of his study explores Immunology relationship to Genetic predisposition. His Autoimmunity study introduces a deeper knowledge of Antibody.
His study in Antibody is interdisciplinary in nature, drawing from both Protein Fragment and Peptide. His Disease study combines topics from a wide range of disciplines, such as Acquired immune system, Interleukin, Proinflammatory cytokine and MHC restriction. He combines subjects such as Transient elastography, Liver disease, Biochemistry, Clinical significance and Immunopathology with his study of Autoantibody.
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Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention.
James Swanson;James Swanson;Jaap Oosterlaan;Michael Andrew Murias;Sabrina Schuck.
Proceedings of the National Academy of Sciences of the United States of America (2000)
The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase.
J. Van De Water;M. E. Gershwin;P. Leung;Aftab Ansari.
Journal of Experimental Medicine (1988)
Cloning, expression, and primary structure of Metapenaeus ensis tropomyosin, the major heat-stable shrimp allergen
Patrick S.C. Leung;Ka Hou Chu;Wing Kuen Chow;Aftab Ansari.
The Journal of Allergy and Clinical Immunology (1994)
IgE reactivity against a cross-reactive allergen in crustacea and mollusca : Evidence for tropomyosin as the common allergen
Patrick S.C. Leung;Wing Kuen Chow;Sean Duffey;Hoi Shan Kwan.
The Journal of Allergy and Clinical Immunology (1996)
Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium*
Carlo F Selmi;Carlo F Selmi;David L. Balkwill;Pietro Invernizzi;Aftab A. Ansari.
Hepatology (2003)
Autoantibodies of primary biliary cirrhosis recognize dihydrolipoamide acetyltransferase and inhibit enzyme function.
J Van de Water;D Fregeau;P Davis;A Ansari.
Journal of Immunology (1988)
Molecular mimicry in primary biliary cirrhosis. Evidence for biliary epithelial expression of a molecule cross-reactive with pyruvate dehydrogenase complex-E2
J. Van De Water;J. Turchany;P. S. C. Leung;J. Lake.
Journal of Clinical Investigation (1993)
The Implication of Vitamin D and Autoimmunity: a Comprehensive Review
Chen-Yen Yang;Patrick S. C. Leung;Iannis E. Adamopoulos;Iannis E. Adamopoulos;M. Eric Gershwin.
Clinical Reviews in Allergy & Immunology (2013)
Autoimmune acute liver failure: proposed clinical and histological criteria.
R. Todd Stravitz;Jay H. Lefkowitch;Robert J. Fontana;M. Eric Gershwin.
Hepatology (2011)
Chemical Xenobiotics and Mitochondrial Autoantigens in Primary Biliary Cirrhosis: Identification of Antibodies against a Common Environmental, Cosmetic, and Food Additive, 2-Octynoic Acid
Katsushi Amano;Katsushi Amano;Patrick S C Leung;Roman Rieger;Chao Quan.
Journal of Immunology (2005)
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