D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 56 Citations 9,415 294 World Ranking 6329 National Ranking 1966

Research.com Recognitions

Awards & Achievements

1987 - Fellow of Alfred P. Sloan Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Catalysis
  • Enzyme

His primary scientific interests are in Organic chemistry, Biochemistry, Primary biliary cirrhosis, Pyruvate dehydrogenase complex and Cystic fibrosis transmembrane conductance regulator. The Organic chemistry study which covers Solid-phase synthesis that intersects with Stereoselectivity and Isoquinoline. His Biochemistry research is multidisciplinary, incorporating elements of Transfection and Cell biology.

The Primary biliary cirrhosis study combines topics in areas such as Autoantibody and Molecular mimicry. The various areas that he examines in his Pyruvate dehydrogenase complex study include Antibody, Hapten and Peptide. His work carried out in the field of Cystic fibrosis transmembrane conductance regulator brings together such families of science as Chloride channel, Flavones, Ion transporter and Cyclic nucleotide-binding domain.

His most cited work include:

  • Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization. (760 citations)
  • "Analogous" Organic Synthesis of Small-Compound Libraries: Validation of Combinatorial Chemistry in Small-Molecule Synthesis (261 citations)
  • Mechanism-based corrector combination restores ΔF508-CFTR folding and function (255 citations)

What are the main themes of his work throughout his whole career to date?

Mark J. Kurth focuses on Organic chemistry, Stereochemistry, Combinatorial chemistry, Cycloaddition and Medicinal chemistry. Mark J. Kurth frequently studies issues relating to Solid-phase synthesis and Organic chemistry. His biological study spans a wide range of topics, including Electrophile, Asymmetric induction, Cystic fibrosis transmembrane conductance regulator and Stereoselectivity.

His Cycloaddition research is multidisciplinary, incorporating perspectives in Hydantoin, Intramolecular force and Nitrile. His Nitrile research integrates issues from Oxide and 1,3-Dipolar cycloaddition. His research on Medicinal chemistry frequently links to adjacent areas such as Ring.

He most often published in these fields:

  • Organic chemistry (30.79%)
  • Stereochemistry (22.25%)
  • Combinatorial chemistry (17.30%)

What were the highlights of his more recent work (between 2011-2021)?

  • Combinatorial chemistry (17.30%)
  • Organic chemistry (30.79%)
  • Davis–Beirut reaction (2.92%)

In recent papers he was focusing on the following fields of study:

Mark J. Kurth mainly investigates Combinatorial chemistry, Organic chemistry, Davis–Beirut reaction, Cycloaddition and Catalysis. His Combinatorial chemistry study incorporates themes from Quinoline, Stereochemistry and Substrate. His specific area of interest is Organic chemistry, where he studies Isoxazole.

Mark J. Kurth interconnects Nitrile, Intramolecular force and Azide in the investigation of issues within Cycloaddition. His Catalysis study integrates concerns from other disciplines, such as Photochemistry and Aryl. His Potentiator research includes elements of Biochemistry and Cystic fibrosis transmembrane conductance regulator.

Between 2011 and 2021, his most popular works were:

  • Mechanism-based corrector combination restores ΔF508-CFTR folding and function (255 citations)
  • One-pot–Two-step Cascade Synthesis of Quinazolinotriazolobenzodiazepines (52 citations)
  • Multicomponent Assembly of Highly Substituted Indoles by Dual Palladium‐Catalyzed Coupling Reactions (48 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Catalysis
  • Enzyme

His primary areas of study are Biochemistry, Molecule, Cycloaddition, Catalysis and Cystic fibrosis transmembrane conductance regulator. His studies in Biochemistry integrate themes in fields like Autoantibody and Innate immune system. His Molecule research is within the category of Organic chemistry.

His work deals with themes such as Combinatorial chemistry, Small Molecule Libraries, Stereochemistry and Nitrile, which intersect with Cycloaddition. His Stereochemistry study combines topics from a wide range of disciplines, such as Biological activity and Adenosine. His Cystic fibrosis transmembrane conductance regulator research incorporates themes from EC50, Potency, Structure–activity relationship and Moiety.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization.

Ann Cassidy-Stone;Jerry E. Chipuk;Elena Ingerman;Cheng Song.
Developmental Cell (2008)

941 Citations

Mechanism-based corrector combination restores ΔF508-CFTR folding and function

Tsukasa Okiyoneda;Guido Veit;Johanna F Dekkers;Miklos Bagdany.
Nature Chemical Biology (2013)

321 Citations

Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium*

Carlo F Selmi;Carlo F Selmi;David L. Balkwill;Pietro Invernizzi;Aftab A. Ansari.
Hepatology (2003)

297 Citations

"Analogous" Organic Synthesis of Small-Compound Libraries: Validation of Combinatorial Chemistry in Small-Molecule Synthesis

Chixu Chen;Lisa A. Ahlberg Randall;R. Bryan Miller;A. Daniel Jones.
Journal of the American Chemical Society (1994)

266 Citations

Carbon-carbon bond forming solid-phase reactions

Beth A. Lorsbach;Mark J. Kurth.
Chemical Reviews (1999)

248 Citations

Novel CFTR Chloride Channel Activators Identified by Screening of Combinatorial Libraries Based on Flavone and Benzoquinolizinium Lead Compounds

Luis J.V. Galietta;Mark F. Springsteel;Masahiro Eda;Edmund J. Niedzinski.
Journal of Biological Chemistry (2001)

234 Citations

Chemical Xenobiotics and Mitochondrial Autoantigens in Primary Biliary Cirrhosis: Identification of Antibodies against a Common Environmental, Cosmetic, and Food Additive, 2-Octynoic Acid

Katsushi Amano;Katsushi Amano;Patrick S C Leung;Roman Rieger;Chao Quan.
Journal of Immunology (2005)

231 Citations

Carbon-carbon bond-forming solid-phase reactions. Part II.

Robert E. Sammelson and;Mark J. Kurth.
Chemical Reviews (2001)

226 Citations

Cyclic amino acid derivatives

Kyung Ho Park;Mark J. Kurth.
Tetrahedron (2002)

200 Citations

Immunoreactivity of Organic Mimeotopes of the E2 Component of Pyruvate Dehydrogenase: Connecting Xenobiotics with Primary Biliary Cirrhosis

S Alice Long;Chao Quan;Judy Van de Water;Michael H Nantz.
Journal of Immunology (2001)

190 Citations

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