1987 - Fellow of Alfred P. Sloan Foundation
His primary scientific interests are in Organic chemistry, Biochemistry, Primary biliary cirrhosis, Pyruvate dehydrogenase complex and Cystic fibrosis transmembrane conductance regulator. The Organic chemistry study which covers Solid-phase synthesis that intersects with Stereoselectivity and Isoquinoline. His Biochemistry research is multidisciplinary, incorporating elements of Transfection and Cell biology.
The Primary biliary cirrhosis study combines topics in areas such as Autoantibody and Molecular mimicry. The various areas that he examines in his Pyruvate dehydrogenase complex study include Antibody, Hapten and Peptide. His work carried out in the field of Cystic fibrosis transmembrane conductance regulator brings together such families of science as Chloride channel, Flavones, Ion transporter and Cyclic nucleotide-binding domain.
Mark J. Kurth focuses on Organic chemistry, Stereochemistry, Combinatorial chemistry, Cycloaddition and Medicinal chemistry. Mark J. Kurth frequently studies issues relating to Solid-phase synthesis and Organic chemistry. His biological study spans a wide range of topics, including Electrophile, Asymmetric induction, Cystic fibrosis transmembrane conductance regulator and Stereoselectivity.
His Cycloaddition research is multidisciplinary, incorporating perspectives in Hydantoin, Intramolecular force and Nitrile. His Nitrile research integrates issues from Oxide and 1,3-Dipolar cycloaddition. His research on Medicinal chemistry frequently links to adjacent areas such as Ring.
Mark J. Kurth mainly investigates Combinatorial chemistry, Organic chemistry, Davis–Beirut reaction, Cycloaddition and Catalysis. His Combinatorial chemistry study incorporates themes from Quinoline, Stereochemistry and Substrate. His specific area of interest is Organic chemistry, where he studies Isoxazole.
Mark J. Kurth interconnects Nitrile, Intramolecular force and Azide in the investigation of issues within Cycloaddition. His Catalysis study integrates concerns from other disciplines, such as Photochemistry and Aryl. His Potentiator research includes elements of Biochemistry and Cystic fibrosis transmembrane conductance regulator.
His primary areas of study are Biochemistry, Molecule, Cycloaddition, Catalysis and Cystic fibrosis transmembrane conductance regulator. His studies in Biochemistry integrate themes in fields like Autoantibody and Innate immune system. His Molecule research is within the category of Organic chemistry.
His work deals with themes such as Combinatorial chemistry, Small Molecule Libraries, Stereochemistry and Nitrile, which intersect with Cycloaddition. His Stereochemistry study combines topics from a wide range of disciplines, such as Biological activity and Adenosine. His Cystic fibrosis transmembrane conductance regulator research incorporates themes from EC50, Potency, Structure–activity relationship and Moiety.
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Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization.
Ann Cassidy-Stone;Jerry E. Chipuk;Elena Ingerman;Cheng Song.
Developmental Cell (2008)
Mechanism-based corrector combination restores ΔF508-CFTR folding and function
Tsukasa Okiyoneda;Guido Veit;Johanna F Dekkers;Miklos Bagdany.
Nature Chemical Biology (2013)
Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium*
Carlo F Selmi;Carlo F Selmi;David L. Balkwill;Pietro Invernizzi;Aftab A. Ansari.
Hepatology (2003)
"Analogous" Organic Synthesis of Small-Compound Libraries: Validation of Combinatorial Chemistry in Small-Molecule Synthesis
Chixu Chen;Lisa A. Ahlberg Randall;R. Bryan Miller;A. Daniel Jones.
Journal of the American Chemical Society (1994)
Carbon-carbon bond forming solid-phase reactions
Beth A. Lorsbach;Mark J. Kurth.
Chemical Reviews (1999)
Novel CFTR Chloride Channel Activators Identified by Screening of Combinatorial Libraries Based on Flavone and Benzoquinolizinium Lead Compounds
Luis J.V. Galietta;Mark F. Springsteel;Masahiro Eda;Edmund J. Niedzinski.
Journal of Biological Chemistry (2001)
Chemical Xenobiotics and Mitochondrial Autoantigens in Primary Biliary Cirrhosis: Identification of Antibodies against a Common Environmental, Cosmetic, and Food Additive, 2-Octynoic Acid
Katsushi Amano;Katsushi Amano;Patrick S C Leung;Roman Rieger;Chao Quan.
Journal of Immunology (2005)
Carbon-carbon bond-forming solid-phase reactions. Part II.
Robert E. Sammelson and;Mark J. Kurth.
Chemical Reviews (2001)
Cyclic amino acid derivatives
Kyung Ho Park;Mark J. Kurth.
Tetrahedron (2002)
Immunoreactivity of Organic Mimeotopes of the E2 Component of Pyruvate Dehydrogenase: Connecting Xenobiotics with Primary Biliary Cirrhosis
S Alice Long;Chao Quan;Judy Van de Water;Michael H Nantz.
Journal of Immunology (2001)
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