D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 55 Citations 11,033 152 World Ranking 7568 National Ranking 176

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

Luis J. V. Galietta mainly focuses on Cystic fibrosis transmembrane conductance regulator, Chloride channel, Cystic fibrosis, Biochemistry and Biophysics. His biological study spans a wide range of topics, including Epithelial sodium channel, Green fluorescent protein, Molecular biology, Apical membrane and Pharmacology. Chloride channel is a subfield of Cell biology that Luis J. V. Galietta tackles.

His Cell biology research incorporates themes from Secretion, Lung and Pathology. His study in Cystic fibrosis is interdisciplinary in nature, drawing from both Channel blocker, Forskolin, Genetic heterogeneity, Pancreatic disease and Haplotype. His research in Biophysics focuses on subjects like Structure–activity relationship, which are connected to Signal transduction, In vivo and Inhibitory postsynaptic potential.

His most cited work include:

  • TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity (939 citations)
  • Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin–induced intestinal fluid secretion (602 citations)
  • Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening (477 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cystic fibrosis transmembrane conductance regulator, Chloride channel, Cystic fibrosis, Cell biology and Biochemistry. As a part of the same scientific family, Luis J. V. Galietta mostly works in the field of Cystic fibrosis transmembrane conductance regulator, focusing on Molecular biology and, on occasion, Cell culture. His study explores the link between Chloride channel and topics such as Potentiator that cross with problems in Gating, Binding site and ΔF508.

His Cystic fibrosis study combines topics in areas such as Cancer research, Immunology, Endoplasmic reticulum, Small molecule and Pharmacology. The concepts of his Cell biology study are interwoven with issues in Respiratory epithelium, Lung, Mucociliary clearance, Transmembrane protein and Ion channel. His biological study deals with issues like Biophysics, which deal with fields such as Ion transporter, Intracellular and Extracellular.

He most often published in these fields:

  • Cystic fibrosis transmembrane conductance regulator (39.69%)
  • Chloride channel (37.11%)
  • Cystic fibrosis (35.05%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cystic fibrosis (35.05%)
  • Cell biology (28.87%)
  • Cystic fibrosis transmembrane conductance regulator (39.69%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cystic fibrosis, Cell biology, Cystic fibrosis transmembrane conductance regulator, Chloride channel and Mutation. The study incorporates disciplines such as Cell culture, Inflammation, Potentiator, Molecular biology and Small molecule in addition to Cystic fibrosis. His Cell biology research incorporates elements of Autophagy, Epithelium, Respiratory epithelium and Ex vivo.

By researching both Cystic fibrosis transmembrane conductance regulator and Surface plasmon resonance, Luis J. V. Galietta produces research that crosses academic boundaries. His research integrates issues of Purinergic receptor and Subcellular localization in his study of Chloride channel. His research in Mutation intersects with topics in Thiazole and Mutant.

Between 2017 and 2021, his most popular works were:

  • Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis (24 citations)
  • Increased expression of ATP12A proton pump in cystic fibrosis airways (22 citations)
  • Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools. (20 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

The scientist’s investigation covers issues in Cystic fibrosis, Mutation, Cystic fibrosis transmembrane conductance regulator, Cell culture and Chloride channel. His Cystic fibrosis study integrates concerns from other disciplines, such as Inflammation, Molecular biology, Disease and Intensive care medicine. Luis J. V. Galietta works mostly in the field of Mutation, limiting it down to topics relating to Mutant and, in certain cases, Pharmacology, Structure–activity relationship, Agonist and Small molecule, as a part of the same area of interest.

In his works, Luis J. V. Galietta undertakes multidisciplinary study on Cystic fibrosis transmembrane conductance regulator and Induced pluripotent stem cell. Luis J. V. Galietta combines subjects such as Purinergic receptor, TRPV4, Intracellular, Calcium signaling and Activator with his study of Chloride channel. As a part of the same scientific study, he usually deals with the Cytokine, concentrating on Respiratory epithelium and frequently concerns with Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

Antonella Caputo;Emanuela Caci;Loretta Ferrera;Nicoletta Pedemonte.
Science (2008)

1203 Citations

Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin–induced intestinal fluid secretion

Tonghui Ma;Jay R. Thiagarajah;Hong Yang;Nitin D. Sonawane.
Journal of Clinical Investigation (2002)

757 Citations

Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening

Nicoletta Pedemonte;Gergely L. Lukacs;Kai Du;Emanuela Caci.
Journal of Clinical Investigation (2005)

609 Citations

Chloride channels as drug targets

Alan S. Verkman;Luis J. V. Galietta.
Nature Reviews Drug Discovery (2009)

481 Citations

Green fluorescent protein-based halide indicators with improved chloride and iodide affinities.

Luis J.V Galietta;Peter M Haggie;A.S Verkman.
FEBS Letters (2001)

360 Citations

Structure and Function of TMEM16 Proteins (Anoctamins)

Nicoletta Pedemonte;Luis J. V. Galietta.
Physiological Reviews (2014)

360 Citations

Discovery of Glycine Hydrazide Pore-occluding CFTR Inhibitors: Mechanism, Structure–Activity Analysis, and In Vivo Efficacy

Chatchai Muanprasat;N.D. Sonawane;Danieli Salinas;Alessandro Taddei.
The Journal of General Physiology (2004)

287 Citations

Nanomolar Affinity Small Molecule Correctors of Defective ΔF508-CFTR Chloride Channel Gating

Hong Yang;Anang A. Shelat;R. Kiplin Guy;Vadiraj S. Gopinath.
Journal of Biological Chemistry (2003)

247 Citations

High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening.

Tonghui Ma;L. Vetrivel;Hong Yang;Nicoletta Pedemonte.
Journal of Biological Chemistry (2002)

235 Citations

Novel CFTR Chloride Channel Activators Identified by Screening of Combinatorial Libraries Based on Flavone and Benzoquinolizinium Lead Compounds

Luis J.V. Galietta;Mark F. Springsteel;Masahiro Eda;Edmund J. Niedzinski.
Journal of Biological Chemistry (2001)

234 Citations

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