What is he best known for?
The fields of study he is best known for:
Frédéric Becq mainly investigates Cystic fibrosis transmembrane conductance regulator, Chloride channel, Biochemistry, Cell biology and Cystic fibrosis.
His Cystic fibrosis transmembrane conductance regulator study improves the overall literature in Internal medicine.
His research in Chloride channel intersects with topics in Transport protein, Wild type, Chloride channel activity, IBMX and Theophylline.
His work in the fields of Biochemistry, such as Secretion, ATP-binding cassette transporter and Chinese hamster ovary cell, intersects with other areas such as Spermatocyte and Sulfate permease.
He has included themes like Vascular smooth muscle and Transfection in his Cell biology study.
Frédéric Becq interconnects Endoplasmic reticulum, Stereochemistry, Miglustat and Pathology in the investigation of issues within Cystic fibrosis.
His most cited work include:
- Interleukin-1β Secretion Is Impaired by Inhibitors of the Atp Binding Cassette Transporter, ABC1 (217 citations)
- ABC1, an ATP Binding Cassette Transporter Required for Phagocytosis of Apoptotic Cells, Generates a Regulated Anion Flux after Expression in Xenopus laevis Oocytes (139 citations)
- Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the α-glucosidase inhibitor miglustat (131 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Cystic fibrosis transmembrane conductance regulator, Cystic fibrosis, Cell biology, Chloride channel and Biochemistry.
Frédéric Becq combines subjects such as Apical membrane, Molecular biology, Endocrinology and Forskolin with his study of Cystic fibrosis transmembrane conductance regulator.
Frédéric Becq focuses mostly in the field of Cystic fibrosis, narrowing it down to topics relating to Mutation and, in certain cases, Phenotype.
His study in Cell biology is interdisciplinary in nature, drawing from both Secretion, Cell culture and Ion transporter.
Frédéric Becq focuses mostly in the field of Chloride channel, narrowing it down to matters related to IBMX and, in some cases, Xanthine.
His research links Biophysics with Biochemistry.
He most often published in these fields:
- Cystic fibrosis transmembrane conductance regulator (52.23%)
- Cystic fibrosis (42.68%)
- Cell biology (38.85%)
What were the highlights of his more recent work (between 2014-2021)?
- Cystic fibrosis (42.68%)
- Cell biology (38.85%)
- Cystic fibrosis transmembrane conductance regulator (52.23%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cystic fibrosis, Cell biology, Cystic fibrosis transmembrane conductance regulator, Chloride channel and Mutation.
His biological study spans a wide range of topics, including Inflammation, Cancer research, Mutant and Potentiator.
His Cell biology study combines topics in areas such as Secretion, Cell and Sertoli cell.
His Cystic fibrosis transmembrane conductance regulator research is multidisciplinary, incorporating elements of Function, Transmembrane protein, Molecular biology, Endoplasmic reticulum and Forskolin.
While the research belongs to areas of Chloride channel, Frédéric Becq spends his time largely on the problem of TRPC6, intersecting his research to questions surrounding TRPM7, TRPV4, Tyrosine kinase and Adenylyl cyclase.
His studies deal with areas such as Phenotype, Epididymis, Internal medicine and Endocrinology as well as Mutation.
Between 2014 and 2021, his most popular works were:
- Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis (29 citations)
- Synthetic deoxynojirimycin derivatives bearing a thiolated, fluorinated or unsaturated N-alkyl chain: identification of potent α-glucosidase and trehalase inhibitors as well as F508del-CFTR correctors. (15 citations)
- SERCA and PMCA pumps contribute to the deregulation of Ca2 + homeostasis in human CF epithelial cells (14 citations)
In his most recent research, the most cited papers focused on:
Frédéric Becq spends much of his time researching Cystic fibrosis transmembrane conductance regulator, Cystic fibrosis, Cell biology, Stereochemistry and Function.
His studies in Cystic fibrosis transmembrane conductance regulator integrate themes in fields like Transient receptor potential channel, TRPV6, Molecular biology, Endoplasmic reticulum and Western blot.
Endoplasmic reticulum is a primary field of his research addressed under Biochemistry.
His biological study spans a wide range of topics, including Mutation, Therapeutic approach, Mutant and Genetic counseling.
Frédéric Becq studies Cell biology, namely Mitochondrion.
His Function study which covers Patch clamp that intersects with Chloride channel.
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