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Aleksander Edelman

Aleksander Edelman

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
6837
World Ranking
16893
National Ranking
712

Overview

Aleksander Edelman is affiliated with Université Paris Cité in France. Their research focuses mainly on Medicine and Biochemistry, Genetics and Molecular Biology, with a significant number of publications related to pulmonary and respiratory medicine.

The scientist's work spans several subfields, including pulmonary and respiratory medicine, molecular biology, cell biology, genetics, and physiology.

Key research topics covered by Edelman include cystic fibrosis research advances, neonatal respiratory health research, tracheal and airway disorders, cellular transport and secretion, bacterial genetics and biotechnology, drug transport and resistance mechanisms, and inhalation and respiratory drug delivery.

Frequent co-authors collaborating with Aleksander Edelman are:

  • Alexandre Hinzpeter
  • Isabelle Sermet-Gaudelus
  • Iwona Pranke
  • B. Chevalier
  • Aurélie Hatton

They frequently publish in several scientific venues, including:

  • Cellular and Molecular Life Sciences
  • Journal of Cystic Fibrosis
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Scientific Reports

Some of Aleksander Edelman's recent papers showcase the focus on cystic fibrosis and related respiratory cellular mechanisms:

  • Theratyping cystic fibrosis patients to guide elexacaftor/tezacaftor/ivacaftor out-of-label prescription, 2023, European Respiratory Journal
  • Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR, 2021, Cellular and Molecular Life Sciences
  • Correlating genotype with phenotype using CFTR-mediated whole-cell Cl currents in human nasal epithelial cells, 2021, The Journal of Physiology
  • Reclassifying inconclusive diagnosis after newborn screening for cystic fibrosis. Moving forward, 2021, Journal of Cystic Fibrosis
  • Differential CFTR-Interactome Proximity Labeling Procedures Identify Enrichment in Multiple SLC Transporters, 2022, International Journal of Molecular Sciences

Best Publications

  • Cytoplasmic regulation of tight-junction permeability: effect of plant cytokinins.

    C. J. Bentzel;B. Hainau;S. Ho;S. W. Hui

  • Purification and reconstitution of chloride channels from kidney and trachea.

    Donald W. Landry;Myles H. Akabas;Christopher Redhead;Aleksander Edelman

  • Molecular cloning and characterization of p64, a chloride channel protein from kidney microsomes.

    D. Landry;S. Sullivan;M. Nicolaides;C. Redhead

  • In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study

    Isabelle Sermet-Gaudelus;Isabelle Sermet-Gaudelus;Michel Renouil;Anne Fajac;Laure Bidou;Laure Bidou

  • Distribution of ClC-2 chloride channel in rat and human epithelial tissues

    Joanna Lipecka;Moëz Bali;Annick Thomas;Pascale Fanen

  • Correction of CFTR function in nasal epithelial cells from cystic fibrosis patients predicts improvement of respiratory function by CFTR modulators

    Iwona M. Pranke;Aurélie Hatton;Juliette Simonin;Jean Philippe Jais

  • Liposome-based Formulation for Intracellular Delivery of Functional Proteins

    Benoît Chatin;Mathieu Mével;Mathieu Mével;Julie Devallière;Julie Devallière;Laurence Dallet

  • NH3 is involved in the NH4+ transport induced by the functional expression of the human Rh C glycoprotein.

    Naziha Bakouh;Fatine Benjelloun;Philippe Hulin;Franck Brouillard

  • Structure-guided combination therapy to potently improve the function of mutant CFTRs

    Guido Veit;Haijin Xu;Elise Dreano;Radu G. Avramescu

  • Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel function in vitro and in vivo.

    Mathieu Le Gars;Delphyne Descamps;Delphine Roussel;Emilie Saussereau

  • Interferon-gamma downregulates CFTR gene expression in epithelial cells.

    F. Besancon;G. Przewlocki;I. Baro;A. S. Hongre

  • Down-regulation of the Anti-inflammatory Protein Annexin A1 in Cystic Fibrosis Knock-out Mice and Patients

    Noura Bensalem;Ana Paula Ventura;Benoît Vallée;Joanna Lipecka

  • Emerging Therapeutic Approaches for Cystic Fibrosis. From Gene Editing to Personalized Medicine.

    Iwona Pranke;Anita Golec;Alexandre Hinzpeter;Aleksander Edelman

  • Effect of plant cytokinins on microfilaments and tight junction permeability.

    C. J. Bentzel;B. Hainau;A. Edelman;T. Anagnostopoulos

  • Determination of intracellular K+ activity in rat kidney proximal tubular cells

    A. Edelman;S. Curci;I. Samaržija;E. Frömter

  • Pseudomonas aeruginosa LasB protease impairs innate immunity in mice and humans by targeting a lung epithelial cystic fibrosis transmembrane regulator-IL-6-antimicrobial-repair pathway

    Vinciane Saint-Criq;Bérengère Villeret;Fabien Bastaert;Saadé Kheir

  • Modulation of the hyperpolarization-activated Cl- current in human intestinal T84 epithelial cells by phosphorylation.

    J Fritsch;A Edelman

  • The testis anion transporter TAT1 (SLC26A8) physically and functionally interacts with the cystic fibrosis transmembrane conductance regulator channel: a potential role during sperm capacitation

    Baptiste Rode;Thassadite Dirami;Thassadite Dirami;Thassadite Dirami;Naziha Bakouh;Naziha Bakouh;Marthe Rizk-Rabin;Marthe Rizk-Rabin;Marthe Rizk-Rabin

  • Discovery of novel potent ΔF508-CFTR correctors that target the nucleotide binding domain

    Norbert Odolczyk;Janine Fritsch;Caroline Norez;Nathalie Servel

  • Basic protocol for transepithelial nasal potential difference measurements

    Daniel Schüler;Isabelle Sermet-Gaudelus;Michael Wilschanski;Manfred Ballmann

Frequent Co-Authors

Isabelle Sermet-Gaudelus
Isabelle Sermet-Gaudelus Necker-Enfants Malades Hospital
Michal Dadlez
Michal Dadlez Polish Academy of Sciences
Gergely L. Lukacs
Gergely L. Lukacs McGill University
Jean-Michel Sallenave
Jean-Michel Sallenave Université Paris Cité
Margarida D. Amaral
Margarida D. Amaral University of Lisbon
Thierry Bienvenu
Thierry Bienvenu Université Paris Cité
Zeger Debyser
Zeger Debyser KU Leuven
Rik Gijsbers
Rik Gijsbers KU Leuven
Michel Goossens
Michel Goossens Grenoble Alpes University

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