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Biology and Biochemistry

D-Index
54
Citations
8175
World Ranking
15836
National Ranking
1244

Overview

Olga Sayanova is affiliated with Rothamsted Research in the United Kingdom. Their research primarily focuses on biochemistry, genetics, and molecular biology, with particular emphasis on molecular biology, biochemistry, renewable energy, sustainability and the environment, biomedical engineering, and biotechnology. The main topics of their work include lipid metabolism and biosynthesis, microbial metabolic engineering and bioproduction, algal biology and biofuel production, biodiesel production and applications, plant tissue culture and regeneration, transgenic plants and applications, as well as CRISPR and genetic engineering.

Olga Sayanova has published extensively in several scientific journals. Key papers include:

  • Overexpression of an endogenous type 2 diacylglycerol acyltransferase in the marine diatom Phaeodactylum tricornutum enhances lipid production and omega-3 long-chain polyunsaturated fatty acid content, 2020, Biotechnology for Biofuels
  • High level accumulation of EPA and DHA in field-grown transgenic Camelina - a multi-territory evaluation of TAG accumulation and heterogeneity, 2020, Plant Biotechnology Journal
  • Plastidial acyl carrier protein Δ9-desaturase modulates eicosapentaenoic acid biosynthesis and triacylglycerol accumulation in Phaeodactylum tricornutum, 2021, The Plant Journal
  • Nutritional enhancement in plants - green and greener, 2020, Current Opinion in Biotechnology
  • Using field evaluation and systematic iteration to rationalize the accumulation of omega-3 long-chain polyunsaturated fatty acids in transgenic Camelina sativa, 2022, Plant Biotechnology Journal

Their frequent coauthors include:

  • Johnathan A. Napier
  • Richard P. Haslam
  • Richard T. Smith
  • Kirsty L. Hassall
  • Lihua Han

Olga Sayanova's work is published primarily in venues such as:

  • Plant Biotechnology Journal
  • Biotechnology for Biofuels
  • The Plant Journal
  • Current Opinion in Biotechnology
  • Algal Research

Best Publications

  • Production of very long chain polyunsaturated omega-3 and omega-6 fatty acids in plants

    Baoxiu Qi;Baoxiu Qi;Tom Fraser;Sam Mugford;Gary Dobson

  • Expression of a borage desaturase cDNA containing an N-terminal cytochrome b5 domain results in the accumulation of high levels of Δ6-desaturated fatty acids in transgenic tobacco

    O. V. Sayanova;M. A. Smith;P. Lapinskas;A. K. Stobart

  • Successful high-level accumulation of fish oil omega-3 long-chain polyunsaturated fatty acids in a transgenic oilseed crop

    Noemi Ruiz-Lopez;Richard P. Haslam;Johnathan A. Napier;Olga Sayanova

  • An alternative to fish oils: Metabolic engineering of oil-seed crops to produce omega-3 long chain polyunsaturated fatty acids.

    Mónica Venegas-Calerón;Olga Sayanova;Johnathan A. Napier

  • Eicosapentaenoic acid: biosynthetic routes and the potential for synthesis in transgenic plants.

    Olga V. Sayanova;Johnathan A. Napier

  • Metabolic engineering of Phaeodactylum tricornutum for the enhanced accumulation of omega-3 long chain polyunsaturated fatty acids.

    Mary L. Hamilton;Richard P. Haslam;Johnathan A. Napier;Olga Sayanova

  • Heterologous reconstitution in yeast of the polyunsaturated fatty acid biosynthetic pathway

    Frédéric Beaudoin;Louise V. Michaelson;Sandra J. Hey;Mervyn J. Lewis

  • A nutritionally-enhanced oil from transgenic Camelina sativa effectively replaces fish oil as a source of eicosapentaenoic acid for fish

    Monica Betancor;Matthew Sprague;Sarah Usher;Olga Sayanova

  • Metabolic engineering of the omega-3 long chain polyunsaturated fatty acid biosynthetic pathway into transgenic plants

    Noemi Ruiz-López;Olga Sayanova;Johnathan A. Napier;Richard P. Haslam

  • Modulation of lipid biosynthesis by stress in diatoms.

    Olga Sayanova;Virginie Mimouni;Lionel Ulmann;Annick Morant-Manceau

  • Identification of Primula fatty acid Δ6-desaturases with n-3 substrate preferences1

    Olga V. Sayanova;Frédéric Beaudoin;Louise V. Michaelson;Peter R. Shewry

  • Evaluation of a high-EPA oil from transgenic Camelina sativa in feeds for Atlantic salmon (Salmo salar L.): Effects on tissue fatty acid composition, histology and gene expression.

    Monica Betancor;Matthew Sprague;Olga Sayanova;Sarah Usher

  • A growing family of cytochrome b5-domain fusion proteins

    Johnathan A. Napier;Olga Sayanova;Petra Sperling;Ernst Heinz

  • Towards the Industrial Production of Omega-3 Long Chain Polyunsaturated Fatty Acids from a Genetically Modified Diatom Phaeodactylum tricornutum

    Mary L. Hamilton;Joanna Warwick;Anya Terry;Michael J. Allen

  • Histidine-41 of the Cytochrome b 5Domain of the Borage Δ6 Fatty Acid Desaturase Is Essential for Enzyme Activity

    Olga Sayanova;Peter R. Shewry;Johnathan A. Napier

  • A Saccharomyces cerevisiae Gene Required for Heterologous Fatty Acid Elongase Activity Encodes a Microsomal β-Keto-reductase

    Frédéric Beaudoin;Ken Gable;Olga Sayanova;Teresa Dunn

  • Fatty acid desaturases from the microalga Thalassiosira pseudonana.

    Thierry Tonon;Olga Sayanova;Louise V. Michaelson;Renwei Qing

  • Overexpression of acetyl-CoA synthetase (ACS) enhances the biosynthesis of neutral lipids and starch in the green microalga Chlamydomonas reinhardtii

    Rocío Rengel;Richard T. Smith;Richard P. Haslam;Olga Sayanova

  • Heterotrophic Production of Omega-3 Long-Chain Polyunsaturated Fatty Acids by Trophically Converted Marine Diatom Phaeodactylum tricornutum

    Mary L. Hamilton;Stephen Powers;Johnathan A. Napier;Olga Sayanova

  • The role of cytochrome b5 fusion desaturases in the synthesis of polyunsaturated fatty acids.

    Johnathan A Napier;Louise V Michaelson;Olga Sayanova

Frequent Co-Authors

Johnathan A. Napier
Johnathan A. Napier Rothamsted Research
Richard P. Haslam
Richard P. Haslam Rothamsted Research
Peter R. Shewry
Peter R. Shewry Rothamsted Research
Colin M. Lazarus
Colin M. Lazarus University of Bristol
Douglas R. Tocher
Douglas R. Tocher Shantou University
Ernst Heinz
Ernst Heinz Universität Hamburg
Ulrich Zähringer
Ulrich Zähringer Research Center Borstel - Leibniz-Center for Medicine and Biosciences
Sten Stymne
Sten Stymne Swedish University of Agricultural Sciences
Philip C. Calder
Philip C. Calder University of Southampton
John A. Pickett
John A. Pickett Cardiff University

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