World's Best Scientists 2026 revealed!
Sakayu Shimizu

Sakayu Shimizu

Award Badge
Chemistry
Japan
2025
Award Badge
Biology and Biochemistry
Japan
2023

D-Index & Metrics

Chemistry

D-Index
91
Citations
25809
World Ranking
1998
National Ranking
107

Biology and Biochemistry

D-Index
91
Citations
26049
World Ranking
2353
National Ranking
144

Research.com Recognitions

  • 2025 - Research.com Chemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2022 - Research.com Chemistry in Japan Leader Award

Overview

Sakayu Shimizu is a researcher affiliated with Kyoto University in Japan, specializing in the fields of biochemistry, genetics, and molecular biology. Their work predominantly focuses on biochemical and molecular research, amino acid enzymes and metabolism, metabolism and genetic disorders, HIV/AIDS drug development and treatment, enzyme structure and function, and enzyme catalysis and immobilization.

Their recent published papers include the following:

  • Gene identification and enzymatic characterization of the initial enzyme in pyrimidine oxidative metabolism, uracil-thymine dehydrogenase (2024, Journal of Bioscience and Bioengineering)
  • Characterization of N-malonylurea hydrolase in the pyrimidine oxidative degradation pathway of Rhodococcus erythropolis JCM 3132 (2025, Bioscience Biotechnology and Biochemistry)
  • Three enzymes of Rhizobium radiobacter involved in the novel metabolism of two naturally occurring bioactive oxidative derivatives of l-isoleucine (2022, Bioscience Biotechnology and Biochemistry)

Shimizu frequently collaborates with other researchers in their field, including Jun Ogawa, Chee-Leong Soong, Kengo Deguchi, Michiki Takeuchi, and Nobuyuki Horinouchi. These collaborations reflect a significant engagement with peers focusing on related biochemical and molecular studies.

The scientist has published mainly in the following venues:

  • Bioscience Biotechnology and Biochemistry
  • Journal of Bioscience and Bioengineering

Their research spans several subfields including molecular biology, biochemistry, clinical biochemistry, infectious diseases, and materials chemistry. This multidisciplinary approach allows for a comprehensive examination of enzyme-related metabolic pathways and genetic factors.

Best Publications

  • Secretion of Flavins by Shewanella Species and Their Role in Extracellular Electron Transfer

    Harald von Canstein;Jun Ogawa;Sakayu Shimizu;Jonathan R. Lloyd

  • Cobalt proteins

    Michihiko Kobayashi;Michihiko Kobayashi;Sakayu Shimizu

  • Biosynthesis and regulation of microbial polyunsaturated fatty acid production.

    Milan Certik;Sakayu Shimizu

  • Metalloenzyme nitrile hydratase: Structure, regulation, and application to biotechnology

    Michihiko Kobayashi;Sakayu Shimizu

  • Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition

    Shigenobu Kishino;Michiki Takeuchi;Si Bum Park;Akiko Hirata

  • Production of conjugated fatty acids by lactic acid bacteria.

    Jun Ogawa;Shigenobu Kishino;Akinori Ando;Satoshi Sugimoto

  • Whole organism biocatalysis.

    Takeru Ishige;Kohsuke Honda;Sakayu Shimizu

  • Production of arachidonic acid by Mortierella fungi

    Yoshifumi Shinmen;Sakayu Shimizu;Kengo Akimoto;Hiroshi Kawashima

  • Conjugated linoleic acid production from linoleic acid by lactic acid bacteria

    Shigenobu Kishino;Jun Ogawa;Yoriko Omura;Kenji Matsumura

  • Enzymatic determination of serum-free fatty acids: a colorimetric method

    Sakayu Shimizu;Yoshiki Tani;Hideaki Yamada;Masayoshi Tabata

  • Bioelectrocatalytic reduction of dioxygen to water at neutral pH using bilirubin oxidase as an enzyme and 2,2′-azinobis (3-ethylbenzothiazolin-6-sulfonate) as an electron transfer mediator

    Seiya Tsujimura;Hirosuke Tatsumi;Jun Ogawa;Sakayu Shimizu

  • Engineering Cytochrome P450 BM-3 for Oxidation of Polycyclic Aromatic Hydrocarbons

    Qing-Shan Li;Jun Ogawa;Rolf D. Schmid;Sakayu Shimizu

  • Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acid biosynthesis

    Sakayu Shimizu;Kengo Akimoto;Yoshifumi Shinmen;Hiroshi Kawashima

  • Conjugated Linoleic Acid Accumulation via 10-Hydroxy-12-Octadecaenoic Acid during Microaerobic Transformation of Linoleic Acid by Lactobacillus acidophilus

    Jun Ogawa;Kenji Matsumura;Shigenobu Kishino;Yoriko Omura

  • Novel bioreduction system for the production of chiral alcohols

    M. Kataoka;K. Kita;M. Wada;Y. Yasohara

  • Synthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate by Escherichia coli transformant cells coexpressing the carbonyl reductase and glucose dehydrogenase genes.

    N. Kizaki;Y. Yasohara;J. Hasegawa;M. Wada

  • ENZYMATIC MICRODETERMINATION OF SERUM FREE FATTY ACIDS

    Sakayu Shimizu;Keiko Inoue;Yoshiki Tani;Hideaki Yamada

  • Microbial and Enzymatic Processes for the Production of Biologically and Chemically Useful Compounds [New Synthetic Methods (69)]

    Hideaki Yamada;Sakayu Shimizu

  • Versatile nitrilases: Nitrile‐hydrolysing enzymes

    Michihiko Kobayashi;Sakayu Shimizu

  • Protective Effects of Sesamin against Liver Damage Caused by Alcohol or Carbon Tetrachloride in Rodents

    Kengo Akimoto;Yoshinori Kitagawa;Tsuyoshi Akamatsu;Nobuaki Hirose

Frequent Co-Authors

Jun Ogawa
Jun Ogawa Kyoto University
Hideaki Yamada
Hideaki Yamada National Institute of Advanced Industrial Science and Technology
Masaru Tanokura
Masaru Tanokura University of Tokyo
Tohru Dairi
Tohru Dairi Hokkaido University
Armin Fiechter
Armin Fiechter ETH Zurich
Rolf D. Schmid
Rolf D. Schmid University of Stuttgart
Kunio Miki
Kunio Miki Kyoto University
Michihiro Sugano
Michihiro Sugano Kyushu University
Mitsuyoshi Ueda
Mitsuyoshi Ueda Kyoto University
Hiroshi Takagi
Hiroshi Takagi Nara Institute of Science and Technology

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students studying Chemistry in the USA, exploring related online degrees can open diverse career pathways. For example, an online associate degree in criminal justice offers a foundation in forensic science roles, where chemical analysis plays a key part in investigations.

Another promising option is pursuing a paralegal career, which often requires specific legal education. Understanding paralegal salary trends can help students assess their financial prospects in this field that blends science and law.

If you’re interested in the pharmaceutical industry, becoming a pharmaceutical sales representative is a viable route. Researching the pharma sales rep salary and career paths can guide you on how to combine your chemistry background with strong communication skills.

For those aiming higher, the path to becoming a pharmacist requires significant commitment. Knowing how long does it take to become a pharmacist helps students plan their education timeline effectively while pursuing advanced chemistry and pharmaceutical coursework.

Best Scientists Citing Sakayu Shimizu

Trending Scientists