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Ruth Lehmann

Ruth Lehmann

D-Index & Metrics

Molecular Biology

D-Index
93
Citations
29946
World Ranking
682
National Ranking
372

Research.com Recognitions

  • 2005 - Member of the National Academy of Sciences
  • 1998 - Fellow of the American Academy of Arts and Sciences

Overview

Ruth Lehmann is affiliated with MIT in the United States and specializes in the field of Biochemistry, Genetics, and Molecular Biology. Their work primarily spans molecular biology, genetics, cellular and molecular neuroscience, plant science, and cell biology.

The researcher's contributions focus on several core topics including developmental biology and gene regulation, neurobiology and insect physiology research, CRISPR and genetic engineering, RNA research and splicing, RNA and protein synthesis mechanisms, RNA modifications and cancer, and chromosomal and genetic variations.

Frequent coauthors in their publications include Torsten U. Banisch, Maija Slaidina, Selena Gupta, Benjamin Lin, and Ruoyu Chen.

Ruth Lehmann has published extensively across multiple scientific venues. The most frequent publication sites are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Development
  • Annual Review of Cell and Developmental Biology
  • Molecular Cell
  • Nature Cell Biology

Selected recent publications demonstrate a focus on Drosophila and RNA biology:

  • Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly, 2022, Science
  • Sequence-Independent Self-Assembly of Germ Granule mRNAs into Homotypic Clusters, 2020, Molecular Cell
  • Large Drosophila germline piRNA clusters are evolutionarily labile and dispensable for transposon regulation, 2021, Molecular Cell
  • A single-cell atlas of the developing Drosophila ovary identifies follicle stem cell progenitors, 2020, Genes & Development
  • A single-cell atlas reveals unanticipated cell type complexity in Drosophila ovaries, 2021, Genome Research

Awards received include membership in the National Academy of Sciences since 2005 and being a Fellow of the American Academy of Arts and Sciences since 1998.

Best Publications

  • Targeted mRNA degradation by double-stranded RNA in vitro

    Thomas Tuschl;Phillip D. Zamore;Ruth Lehmann;David P. Bartel

  • oskar organizes the germ plasm and directs localization of the posterior determinant nanos

    Anne Ephrussi;Laura K. Dickinson;Ruth Lehmann

  • Induction of germ cell formation by oskar.

    Anne Ephrussi;Ruth Lehmann

  • Determination of anteroposterior polarity in Drosophila

    Christiane Nüsslein-Volhard;Hans Georg Frohnhöfer;Ruth Lehmann

  • Regulation of zygotic gene expression in Drosophila primordial germ cells.

    Mark Van Doren;Anne L. Williamson;Ruth Lehmann

  • Nanos is the localized posterior determinant in Drosophila

    Charlotte Wang;Ruth Lehmann

  • On the phenotype and development of mutants of early neurogenesis inDrosophila melanogaster.

    Ruth Lehmann;Fernando Jiménez;Ursula Dietrich;José A. Campos-Ortega

  • The Transgenic RNAi Project at Harvard Medical School: Resources and Validation

    Lizabeth A. Perkins;Laura Holderbaum;Rong Tao;Yanhui Hu

  • Nanos and Pumilio have critical roles in the development and function of Drosophila germline stem cells

    Alexandria Forbes;Ruth Lehmann

  • Abdominal segmentation, pole cell formation, and embryonic polarity require the localized activity of oskar, a maternal gene in drosophila

    Ruth Lehmann;Christiane Nüsslein-Volhard

  • Mechanisms guiding primordial germ cell migration: strategies from different organisms

    Brian E. Richardson;Ruth Lehmann

  • Translational regulation in development.

    Daniel Curtis;Ruth Lehmann;Phillip D Zamore

  • The chemokine SDF1/CXCL12 and its receptor CXCR4 regulate mouse germ cell migration and survival

    Kathleen A. Molyneaux;Hélène Zinszner;Prabhat S. Kunwar;Kyle Schaible

  • Localization of nanos RNA controls embryonic polarity

    Elizabeth R. Gavis;Ruth Lehmann

  • The maternal gene nanos has a central role in posterior pattern formation of the Drosophila embryo.

    R. Lehmann;C. Nusslein-Volhard

  • Finger protein of novel structure encoded by hunchback, a second member of the gap class of Drosophila segmentation genes

    Diethard Tautz;Ruth Lehmann;Harald Schnürch;Reinhard Schuh

  • The Pumilio protein binds RNA through a conserved domain that defines a new class of RNA-binding proteins.

    P D Zamore;J R Williamson;R Lehmann

  • In situ hybridization to RNA

    Ruth Lehmann;Diethard Tautz

  • Translational regulation of nanos by RNA localization

    Elizabeth Rose Gavis;Ruth Lehmann

  • The Drosophila posterior-group gene nanos functions by repressing hunchback activity.

    Vivian Irish;Ruth Lehmann;Michael Akam

Frequent Co-Authors

Phillip D. Zamore
Phillip D. Zamore University of Massachusetts Chan Medical School
Gregory J. Hannon
Gregory J. Hannon University of Cambridge
Anne Ephrussi
Anne Ephrussi European Bioinformatics Institute
Diethard Tautz
Diethard Tautz Max Planck Society
José A. Campos-Ortega
José A. Campos-Ortega University of Cologne
Rui-Ming Xu
Rui-Ming Xu Chinese Academy of Sciences
Herbert Jäckle
Herbert Jäckle Max Planck Society
Norbert Perrimon
Norbert Perrimon Harvard University

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