World's Best Scientists 2026 revealed!

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Genetics

D-Index
104
Citations
68255
World Ranking
639
National Ranking
323

Molecular Biology

D-Index
104
Citations
68255
World Ranking
455
National Ranking
256

Research.com Recognitions

  • 2014 - Fellow, National Academy of Inventors

Overview

Phillip D. Zamore is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant number of publications in these fields. Additional research interests include agricultural and biological sciences.

The scientist's work spans various subfields, including molecular biology, plant science, cancer research, genetics, and public health. Their research covers several main topics such as chromosomal and genetic variations, CRISPR and genetic engineering, advanced biosensing and bioanalysis techniques, microRNA in disease regulation, RNA research and splicing, RNA interference and gene delivery, and RNA modifications and cancer.

Phillip D. Zamore has contributed to multiple publications in frequent venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • Nature Reviews Molecular Cell Biology
  • Nature
  • Nature Genetics

Recent papers authored or co-authored by Phillip D. Zamore include:

  • The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility, 2020, Nature Genetics
  • Thermus thermophilus Argonaute Functions in the Completion of DNA Replication, 2020, Cell
  • Relaxed targeting rules help PIWI proteins silence transposons, 2023, Nature
  • Terminal modification, sequence, length, and PIWI-protein identity determine piRNA stability, 2021, Molecular Cell
  • GTSF1 accelerates target RNA cleavage by PIWI-clade Argonaute proteins, 2022, Nature

Frequent co-authors collaborating with Phillip D. Zamore include:

  • Ildar Gainetdinov
  • Amena Arif
  • Karina Jouravleva
  • Katharine Cecchini
  • Deniz M. Özata

Recognition of Phillip D. Zamore's contributions includes being named a Fellow of the National Academy of Inventors in 2014.

Best Publications

  • RNAi: Double-Stranded RNA Directs the ATP-Dependent Cleavage of mRNA at 21 to 23 Nucleotide Intervals

    Phillip D. Zamore;Thomas Tuschl;Phillip A. Sharp;David P. Bartel

  • Asymmetry in the assembly of the RNAi enzyme complex.

    Dianne S. Schwarz;György Hutvágner;Tingting Du;Zuoshang Xu

  • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA.

    György Hutvágner;Juanita McLachlan;Amy E. Pasquinelli;Éva Bálint

  • A microRNA in a multiple-turnover RNAi enzyme complex.

    György Hutvágner;Phillip D. Zamore

  • Small silencing RNAs: an expanding universe

    Megha Ghildiyal;Phillip D. Zamore

  • ATP requirements and small interfering RNA structure in the RNA interference pathway.

    Antti Nykänen;Benjamin Haley;Phillip D. Zamore

  • Ribo-gnome: the big world of small RNAs

    Phillip D. Zamore;Benjamin Haley

  • Targeted mRNA degradation by double-stranded RNA in vitro

    Thomas Tuschl;Phillip D. Zamore;Ruth Lehmann;David P. Bartel

  • A Distinct Small RNA Pathway Silences Selfish Genetic Elements in the Germline

    Vasily V. Vagin;Alla A. Sigova;Chengjian Li;Herve Seitz

  • Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

    Christian B. Matranga;Yukihide Tomari;Chanseok Shin;David P. Bartel

  • Diversifying microRNA sequence and function

    Stefan L. Ameres;Phillip D. Zamore

  • Perspective: machines for RNAi

    Yukihide Tomari;Phillip D. Zamore

  • A biochemical framework for RNA silencing in plants

    Guiliang Tang;Brenda J. Reinhart;David P. Bartel;Phillip D. Zamore

  • Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

    Benjamin R. Carone;Lucas Fauquier;Naomi Habib;Jeremy M. Shea

  • microPrimer: the biogenesis and function of microRNA

    Tingting Du;Phillip D. Zamore

  • PIWI-interacting RNAs: small RNAs with big functions

    Deniz M. Ozata;Ildar Gainetdinov;Ansgar Zoch;Dónal O’Carroll

  • Sequence-specific inhibition of small RNA function

    Gyorgy Hutvagner;Phillip D. Zamore

  • Rna sequence-specific mediators of rna interference

    Thomas Tuschl;Phillip D. Zamore;Phillip A. Sharp;David P. Bartel

  • RNAi: nature abhors a double-strand.

    György Hutvágner;Phillip D Zamore

  • Molecular biology. RNA interference

    P A Sharp;P D Zamore

Frequent Co-Authors

Zhiping Weng
Zhiping Weng University of Massachusetts Chan Medical School
Thomas Tuschl
Thomas Tuschl Rockefeller University
Neil Aronin
Neil Aronin University of Massachusetts Chan Medical School
Yukihide Tomari
Yukihide Tomari University of Tokyo
William E. Theurkauf
William E. Theurkauf University of Massachusetts Chan Medical School
Guiliang Tang
Guiliang Tang Michigan Technological University
Craig C. Mello
Craig C. Mello University of Massachusetts Chan Medical School

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