2026 John J. Rossi: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	117	286	262	170	154	625	61622

Overview

John J. Rossi is affiliated with the City Of Hope National Medical Center in the United States. Their research spans topics primarily within biochemistry, genetics, and molecular biology, and extends into medicine. The scientist has a significant focus on molecular biology, immunology, oncology, cancer research, and pulmonary and respiratory medicine.

The main areas of study in Rossi's work include RNA interference and gene delivery, advanced biosensing and bioanalysis techniques, RNA and protein synthesis mechanisms, RNA research and splicing, cancer immunotherapy and biomarkers, CRISPR and genetic engineering, and RNA modifications related to cancer.

Their notable recent papers include:

"MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial" (2020) published in Clinical Cancer Research
"Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer" (2021) published in Clinical Cancer Research
"siRNA Drugs: Here to Stay" (2021) published in Molecular Therapy
"Synthesis and use of an amphiphilic dendrimer for siRNA delivery into primary immune cells" (2020) published in Nature Protocols
"Uncovering Differently Expressed Markers and Heterogeneity on Human Pancreatic Cancer" (2020) published in Translational Oncology

Rossi has collaborated frequently with researchers including Nagy Habib, Vikash Reebye, Min-Sun Song, Mikael H. Sodergren, and Kai-Wen Huang.

The scientist's publications have appeared most commonly in the following venues:

Molecular Therapy - Nucleic Acids
Molecular Therapy
bioRxiv (Cold Spring Harbor Laboratory)
Cancer Research
Clinical Cancer Research

Best Publications

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma

Sattva S. Neelapu;Frederick L. Locke;Nancy L. Bartlett;Lazaros J. Lekakis

5830
Citations
Aptamers as targeted therapeutics: current potential and challenges

Jiehua Zhou;John Rossi

1782
Citations
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

Nan Sook Lee;Taikoh Dohjima;Gerhard Bauer;Haitang Li

1601
Citations
Unlocking the potential of the human genome with RNA interference

Gregory J. Hannon;John J. Rossi

1537
Citations
The promises and pitfalls of RNA-interference-based therapeutics

Daniela Castanotto;John J. Rossi

1523
Citations
Strategies for silencing human disease using RNA interference.

Daniel H. Kim;John J. Rossi

1367
Citations
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

Dong-Ho Kim;Mark A Behlke;Scott D Rose;Mi-Sook Chang

1214
Citations
The current state and future directions of RNAi-based therapeutics.

Ryan L. Setten;Ryan L. Setten;John J. Rossi;John J. Rossi;Si-ping Han;Si-ping Han

1149
Citations
RNAi Therapeutics: Principles, Prospects and Challenges

Lars Aagaard;John J. Rossi

1139
Citations
RNA-based therapeutics: current progress and future prospects.

John C. Burnett;John J. Rossi

1077
Citations
Ribozymes as potential anti-HIV-1 therapeutic agents.

Nava Sarver;Edouard M. Cantin;Pairoj S. Chang;Pairoj S. Chang;John A. Zaia

996
Citations
MicroRNA-directed transcriptional gene silencing in mammalian cells.

Daniel H. Kim;Pål Sætrom;Ola Snøve;John J. Rossi

894
Citations
MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.

Mitsuo Kato;Jane Zhang;Mei Wang;Linda Lanting

879
Citations
TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN.

Mitsuo Kato;Sumanth Putta;Mei Wang;Hang Yuan

687
Citations
Approaches for the sequence-specific knockdown of mRNA.

Lisa J Scherer;John J Rossi

678
Citations
Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels

James N. Kochenderfer;Robert P.T. Somerville;Tangying Lu;Victoria Shi

593
Citations
Current progress of siRNA/shRNA therapeutics in clinical trials

John C. Burnett;John J. Rossi;John J. Rossi;Katrin Tiemann

591
Citations
Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase.

Dong-Ho Kim;Michael Longo;Young Han;Patric Lundberg

550
Citations
Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells

Daniel H Kim;Louisa M Villeneuve;Kevin V Morris;John J Rossi

543
Citations
MicroRNAs in Disease and Potential Therapeutic Applications

Harris S Soifer;John J Rossi;Pål Sætrom

510
Citations

Frequent Co-Authors

John A. Zaia City Of Hope National Medical Center

Adrian Bot MannKind Corporation (United States)

Kevin V. Morris City of Hope

Ramesh Akkina Colorado State University

Stephen J. Forman City Of Hope National Medical Center

Xiwei Wu City Of Hope National Medical Center

Ling Peng Aix-Marseille University

Rama Natarajan City Of Hope National Medical Center

Arthur D. Riggs City Of Hope National Medical Center

Hans Peter Kiem Fred Hutchinson Cancer Research Center

External Links

Personal website of John J. Rossi

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