World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
79
Citations
18913
World Ranking
1051
National Ranking
550

Overview

Peixuan Guo is affiliated with The Ohio State University in the United States. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Ecology, Biomedical Engineering, Cancer Research, and Oncology.

The scientist's work covers significant topics such as RNA Interference and Gene Delivery, Advanced Biosensing and Bioanalysis Techniques, Bacteriophages and Microbial Interactions, RNA and Protein Synthesis Mechanisms, MicroRNA in Disease Regulation, Extracellular Vesicles in Disease, and Nanopore and Nanochannel Transport Studies.

Guo has collaborated frequently with several researchers, including Daniel W. Binzel, Xin Li, Hongzhi Wang, Dan Shu, and Kai Jin. These partnerships have contributed to a robust body of work in their fields of study.

Their publications have appeared repeatedly in leading journals and venues such as Nanomedicine Nanotechnology Biology and Medicine, Molecular Therapy - Nucleic Acids, Molecular Pharmaceutics, ACS Nano, and Biomaterials. These outlets reflect the interdisciplinary and applied nature of the research.

Among recent papers authored by or associated with Peixuan Guo are:

  • Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy (2020, Nature Communications)
  • Thermostability, Tunability, and Tenacity of RNA as Rubbery Anionic Polymeric Materials in Nanotechnology and Nanomedicine-Specific Cancer Targeting with Undetectable Toxicity (2021, Chemical Reviews)
  • Multivalent rubber-like RNA nanoparticles for targeted co-delivery of paclitaxel and MiRNA to silence the drug efflux transporter and liver cancer drug resistance (2020, Journal of Controlled Release)
  • RNA Nanoparticles as Rubber for Compelling Vessel Extravasation to Enhance Tumor Targeting and for Fast Renal Excretion to Reduce Toxicity (2020, ACS Nano)
  • Non-Small-Cell Lung Cancer Regression by siRNA Delivered Through Exosomes That Display EGFR RNA Aptamer (2021, Nucleic Acid Therapeutics)

Best Publications

  • The emerging field of RNA nanotechnology

    Peixuan Guo

  • Solid-state and biological nanopore for real-time sensing of single chemical and sequencing of DNA

    Farzin Haque;Jinghong Li;Hai-Chen Wu;Xing-Jie Liang

  • Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for delivery of therapeutics.

    Dan Shu;Yi Shu;Farzin Haque;Sherine Abdelmawla

  • Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression

    Fengmei Pi;Daniel W. Binzel;Tae Jin Lee;Tae Jin Lee;Zhefeng Li

  • Inter-RNA Interaction of Phage φ29 pRNA to Form a Hexameric Complex for Viral DNA Transportation

    Peixuan Guo;Chunlin Zhang;Chaoping Chen;Kyle Garver

  • A small viral RNA is required for in vitro packaging of bacteriophage phi 29 DNA

    Peixuan Guo;Stephen Erickson;Dwight Anderson

  • Engineering RNA for Targeted siRNA Delivery and Medical Application

    Peixuan Guo;Oana Coban;Nicholas M Snead;Joe Trebley

  • Advancement of the Emerging Field of RNA Nanotechnology.

    Daniel Jasinski;Farzin Haque;Daniel W Binzel;Peixuan Guo

  • Translocation of double-stranded DNA through membrane-adapted phi29 motor protein nanopores

    David Wendell;Peng Jing;Jia Geng;Varuni Subramaniam;Varuni Subramaniam

  • Prohead and DNA-gp3-dependent ATPase activity of the DNA packaging protein gp16 of bacteriophage φ29☆

    Peixuan Guo;Charlene Peterson;Dwight Anderson

  • Controllable self-assembly of nanoparticles for specific delivery of multiple therapeutic molecules to cancer cells using RNA nanotechnology.

    Annette Khaled;Songchuan Guo;Feng Li;Peixuan Guo

  • Systemic Delivery of Anti-miRNA for Suppression of Triple Negative Breast Cancer Utilizing RNA Nanotechnology.

    Dan Shu;Hui Li;Yi Shu;Gaofeng Xiong

  • Stable RNA nanoparticles as potential new generation drugs for cancer therapy

    Yi Shu;Fengmei Pi;Ashwani Sharma;Mehdi Rajabi

  • Bottom-up Assembly of RNA Arrays and Superstructures as Potential Parts in Nanotechnology.

    Dan Shu;Wulf-Dieter Moll;Zhaoxiang Deng;Chengde Mao

  • Specific delivery of therapeutic RNAs to cancer cells via the dimerization mechanism of phi29 motor pRNA.

    Songchuan Guo;Nuska Tschammer;Sulma Mohammed;Peixuan Guo

  • Ultrastable Synergistic Tetravalent RNA Nanoparticles for Targeting to Cancers

    Farzin Haque;Dan Shu;Yi Shu;Luda S. Shlyakhtenko

  • RNA nanotechnology: engineering, assembly and applications in detection, gene delivery and therapy.

    Peixuan Guo

  • Counting of six pRNAs of phi29 DNA-packaging motor with customized single-molecule dual-view system

    Dan Shu;Hui Zhang;Jiashun Jin;Peixuan Guo

  • A defined system for in vitro packaging of DNA-gp3 of the Bacillus subtilis bacteriophage phi 29

    Peixuan Guo;Shelley Grimes;Dwight Anderson

  • Fabrication of 14 different RNA nanoparticles for specific tumor targeting without accumulation in normal organs

    Yi Shu;Farzin Haque;Dan Shu;Wei Li

Frequent Co-Authors

B. Mark Evers
B. Mark Evers University of Kentucky
Wah Chiu
Wah Chiu Stanford University
Dwight L. Anderson
Dwight L. Anderson University of Minnesota
Yuri L. Lyubchenko
Yuri L. Lyubchenko University of Nebraska Medical Center
Carlo M. Croce
Carlo M. Croce The Ohio State University
Zhifeng Shao
Zhifeng Shao Shanghai Jiao Tong University
Jeong-Woo Choi
Jeong-Woo Choi Sogang University
Xing-Jie Liang
Xing-Jie Liang National Center for Nanoscience and Technology, China
Balveen Kaur
Balveen Kaur Augusta University
Chia-Yang Liu
Chia-Yang Liu Indiana University

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