World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
50
Citations
8109
World Ranking
14483
National Ranking
2250

Research.com Recognitions

  • 2000 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Zhifeng Shao is affiliated with Shanghai Jiao Tong University in China and focuses on research within the broad field of Biochemistry, Genetics and Molecular Biology. Their work primarily spans molecular biology, biophysics, immunology, structural biology, and plant science.

The scientist has contributed extensively to topics including genomics and chromatin dynamics, single-cell and spatial transcriptomics, gene expression and cancer classification, RNA modifications and cancer, as well as advanced microscopy and cell image analysis techniques.

Frequent publication venues for Zhifeng Shao include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • Genomics Proteomics & Bioinformatics
  • Acta Biochimica et Biophysica Sinica
  • Research Square (Research Square)

Collaboration is a notable aspect of their work, with frequent co-authors such as Daniel M. Czajkowsky, Hua Li, Yan Guo, Chuansheng Hu, and Qiu Sun.

Recent papers authored by Zhifeng Shao include:

  • Digital colloid-enhanced Raman spectroscopy by single-molecule counting, 2024, Nature
  • CHROMATIX: computing the functional landscape of many-body chromatin interactions in transcriptionally active loci from deconvolved single cells, 2020, Genome biology
  • High-resolution single-cell 3D-models of chromatin ensembles during Drosophila embryogenesis, 2021, Nature Communications
  • Monocytic THP-1 cells diverge significantly from their primary counterparts: a comparative examination of the chromosomal conformations and transcriptomes, 2021, Hereditas
  • Nanomechanical Induction of Autophagy-Related Fluorescence in Single Cells with Atomic Force Microscopy, 2021, Advanced Science

Zhifeng Shao was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2000.

Best Publications

  • Vertical collapse of a cytolysin prepore moves its transmembrane β‐hairpins to the membrane

    Daniel M Czajkowsky;Eileen M Hotze;Zhifeng Shao;Rodney K Tweten

  • The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH

    Daniel M. Czajkowsky;Hideki Iwamoto;Timothy L. Cover;Zhifeng Shao

  • Atomic Force Microscopy of Cholera Toxin B-oligomers Bound to Bilayers of Biologically Relevant Lipids

    Jianxun Mou;Jie Yang;Zhifeng Shao

  • High-resolution atomic-force microscopy of DNA: the pitch of the double helix.

    Jianxun Mou;Daniel M. Czajkowsky;Yiyi Zhang;Zhifeng Shao

  • The human IgM pentamer is a mushroom-shaped molecule with a flexural bias

    Daniel M. Czajkowsky;Zhifeng Shao

  • Self-assembling subnanometer pores with unusual mass-transport properties

    Xibin Zhou;Guande Liu;Kazuhiro Yamato;Yi Shen

  • Borg/septin interactions and the assembly of mammalian septin heterodimers, trimers, and filaments.

    Peter J. Sheffield;Carey J. Oliver;Brandon E. Kremer;Sitong Sheng

  • Self-Assembling Organic Nanotubes with Precisely Defined, Sub-nanometer Pores: Formation and Mass Transport Characteristics

    Bing Gong;Zhifeng Shao

  • Alcohol induces interdigitated domains in unilamellar phosphatidylcholine bilayers.

    Jianxun Mou;Jie Yang;C. Huang;Zhifeng Shao

  • Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin.

    Mark S. McClain;Hideki Iwamoto;Ping Cao;Arlene D. Vinion-Dubiel

  • Progress in high resolution atomic force microscopy in biology.

    Zhifeng Shao;Jie Yang

  • Highly Conducting Transmembrane Pores Formed by Aromatic Oligoamide Macrocycles

    Amber Jade Helsel;Amy L. Brown;Kazuhiro Yamato;Wen Feng

  • VacA from Helicobacter pylori: a hexameric chloride channel.

    Hideki Iwamoto;Daniel M. Czajkowsky;Timothy L. Cover;Gabor Szabo

  • New approach for atomic force microscopy of membrane proteins. The imaging of cholera toxin.

    Jie Yang;Lukas K. Tamm;Thomas W. Tillack;Zhifeng Shao

  • Staphylococcal alpha-hemolysin can form hexamers in phospholipid bilayers.

    Daniel M Czajkowsky;Sitong Sheng;Zhifeng Shao

  • A dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation

    Arlene D. Vinion-Dubiel;Mark S. McClain;Daniel M. Czajkowsky;Hideki Iwamoto

  • Sub-kb Hi-C in D . melanogaster reveals conserved characteristics of TADs between insect and mammalian cells

    Qi Wang;Qiu Sun;Daniel M. Czajkowsky;Zhifeng Shao

  • A dimer as a building block in assembling RNA. A hexamer that gears bacterial virus phi29 DNA-translocating machinery.

    Chaoping Chen;Sitong Sheng;Zhifeng Shao;Peixuan Guo

  • Monomer-monomer interactions drive the prepore to pore conversion of a β-barrel-forming cholesterol-dependent cytolysin

    Eileen M. Hotze;Alejandro P. Heuck;Daniel M. Czajkowsky;Zhifeng Shao

  • Tris(hydroxymethyl)aminomethane (C4H11NO3) induced a ripple phase in supported unilamellar phospholipid bilayers.

    Jianxun Mou;Jie Yang;Zhifeng Shao

  • Atomic force microscopy of DNA molecules

    Jie Yang;Kunio Takeyasu;Zhifeng Shao

  • The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH (gastritisyulcersyAB toxinsyVacAymembrane protein)

    Daniel M. Czajkowsky;Hideki Iwamoto;Timothy L. Cover;Zhifeng Shao

Frequent Co-Authors

Bing Gong
Bing Gong University at Buffalo, State University of New York
Bingya Liu
Bingya Liu Shanghai Jiao Tong University
Timothy L. Cover
Timothy L. Cover Vanderbilt University Medical Center
Jun Hu
Jun Hu Chinese Academy of Sciences
Zongli Lin
Zongli Lin University of Virginia
Avril V. Somlyo
Avril V. Somlyo University of Virginia
Peixuan Guo
Peixuan Guo The Ohio State University
Rodney K. Tweten
Rodney K. Tweten University of Oklahoma Health Sciences Center
Ali Salanti
Ali Salanti Copenhagen University Hospital
Xiao Cheng Zeng
Xiao Cheng Zeng City University of Hong Kong

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