What is he best known for?
The fields of study he is best known for:
James C. Whisstock mainly investigates Biochemistry, Protein structure, Cell biology, Perforin and Serpin.
His Biochemistry research incorporates elements of Biophysics and In vivo.
James C. Whisstock has researched Protein structure in several fields, including Theoretical computer science, Protein secondary structure, Peptide sequence, Conformational change and Reactive center.
The various areas that James C. Whisstock examines in his Cell biology study include Inflammation, Receptor, Immune system and Platelet.
His research on Perforin also deals with topics like
- Complement membrane attack complex that connect with fields like Cholesterol-dependent cytolysin,
- Cell membrane, which have a strong connection to Transmembrane protein.
His study in Serpin is interdisciplinary in nature, drawing from both Phylogenetics, Antithrombin and Function.
His most cited work include:
- Prediction of protein function from protein sequence and structure. (1202 citations)
- The serpins are an expanding superfamily of structurally similar but functionally diverse proteins - Evolution, mechanism of inhibition, novel functions, and a revised nomenclature (1046 citations)
- MUSTANG: a multiple structural alignment algorithm. (563 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Biochemistry, Cell biology, Serpin, Protein structure and Perforin.
His study in Protease, Enzyme, Proteases, Peptide sequence and Binding site falls within the category of Biochemistry.
His studies in Enzyme integrate themes in fields like Amino acid, Plasmodium falciparum and Aminopeptidase.
He combines subjects such as Drosophila melanogaster, Drosophila Protein, Secretion and Cell membrane with his study of Cell biology.
His research integrates issues of Crystallography, Molecular biology and Biophysics, Conformational change in his study of Serpin.
His Complement membrane attack complex research extends to Perforin, which is thematically connected.
He most often published in these fields:
- Biochemistry (41.03%)
- Cell biology (33.15%)
- Serpin (21.47%)
What were the highlights of his more recent work (between 2015-2021)?
- Cell biology (33.15%)
- Perforin (18.48%)
- Complement membrane attack complex (10.87%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Cell biology, Perforin, Complement membrane attack complex, MACPF and Plasmin.
His biological study spans a wide range of topics, including Drosophila melanogaster and Drosophila Protein.
Cytotoxic T cell and Biochemistry are the subject areas of his Perforin study.
His work carried out in the field of Biochemistry brings together such families of science as Pathogen and Myeloma protein.
James C. Whisstock has included themes like Biophysics, Macrophage and Transmembrane protein in his Complement membrane attack complex study.
His MACPF research includes themes of Pore forming protein and Cholesterol-dependent cytolysin.
Between 2015 and 2021, his most popular works were:
- Correction: Corrigendum: N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin (70 citations)
- Structure of the poly-C9 component of the complement membrane attack complex. (66 citations)
- Understanding CD30 biology and therapeutic targeting: a historical perspective providing insight into future directions (61 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Perforin, Cell biology, MACPF, Genetics and Biophysics.
As part of his research on Perforin, studies on Cytotoxic T cell and Biochemistry are part of the effort.
Many of his research projects under Cytotoxic T cell are closely connected to Electron microscope with Electron microscope, tying the diverse disciplines of science together.
His Cell biology research is multidisciplinary, incorporating perspectives in Mutation, Cell, Liver infection and Hepatocyte growth factor.
His MACPF research focuses on subjects like Granzyme B, which are linked to Natural killer cell, Secretion, Degranulation and Endoplasmic reticulum.
His Biophysics study integrates concerns from other disciplines, such as Nanotechnology, Protein domain, Membrane, Membrane protein and Complement membrane attack complex.
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