2026 David A. Lomas: Medicine Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Medicine	120	3745	3507	370	355	585	54392

Overview

David A. Lomas is affiliated with University College London in the United Kingdom. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a particular focus on pulmonary and respiratory medicine, cancer research, molecular biology, cell biology, and oncology.

Their work covers several main topics of study, including:

Protease and Inhibitor Mechanisms
Peptidase Inhibition and Analysis
Chronic Obstructive Pulmonary Disease (COPD) Research
Signaling Pathways in Disease
Endoplasmic Reticulum Stress and Disease
Trace Elements in Health
Blood Coagulation and Thrombosis Mechanisms

David A. Lomas has a publication record that includes papers in a number of prominent venues. Frequent publication venues are:

bioRxiv (Cold Spring Harbor Laboratory)
European Respiratory Journal
FEBS Journal
EMBO Molecular Medicine
Science Advances

Recent published papers demonstrate a focus on alpha-1 antitrypsin deficiency and related molecular and structural biology, including:

"Alpha ₁ -Antitrypsin Deficiency," 2020, New England Journal of Medicine
"Hepatobiliary phenotypes of adults with alpha-1 antitrypsin deficiency," 2021, Gut
"The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins: EVOLUTION, MECHANISM OF INHIBITION, NOVEL FUNCTIONS, AND A REVISED NOMENCLATURE," 2021, UNC Libraries
"Development of a small molecule that corrects misfolding and increases secretion of Z α ₁ -antitrypsin," 2021, EMBO Molecular Medicine
"The structural basis for Z α ₁ -antitrypsin polymerization in the liver," 2020, Science Advances

David A. Lomas collaborates frequently with several coauthors, including:

James A. Irving
Riccardo Ronzoni
Alistair M. Jagger
Annamaria Fra
Aileen Marshall

Best Publications

Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease

John R. Hurst;Jørgen Vestbo;Jørgen Vestbo;Antonio Anzueto;Nicholas Locantore

3465
Citations
Characterisation of COPD heterogeneity in the ECLIPSE cohort

Àlvar Agustí;Peter Ma Calverley;Bartolome R Celli;Harvey O Coxson

1496
Citations
Genetic mechanisms of critical illness in Covid-19.

E. Pairo-Castineira;E. Pairo-Castineira;S. Clohisey;L. Klaric;A. D. Bretherick

1445
Citations
Acute Exacerbations of Chronic Obstructive Pulmonary Disease: Identification of Biologic Clusters and Their Biomarkers

Mona Bafadhel;Susan McKenna;Sarah Terry;Vijay Mistry

1269
Citations
The mechanism of Z alpha 1-antitrypsin accumulation in the liver.

D A Lomas;D L Evans;J T Finch;R W Carrell

1231
Citations
Changes in forced expiratory volume in 1 second over time in copd

Jørgen Vestbo;Jørgen Vestbo;Lisa D. Edwards;Paul D. Scanlon;Julie C. Yates

1106
Citations
Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD

David A. Lipson;Frank Barnhart;Noushin Brealey;Jean Brooks

1089
Citations
Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype.

Alvar Agustí;Lisa D. Edwards;Stephen I. Rennard;William MacNee

973
Citations
A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

Sreekumar G. Pillai;Dongliang Ge;Guohua Zhu;Xiangyang Kong

872
Citations
Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE).

J Vestbo;W Anderson;H O Coxson;C Crim

802
Citations
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

Kosuke Yusa;S. Tamir Rashid;Helene Strick-Marchand;Helene Strick-Marchand;Ignacio Varela

783
Citations
Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells

S. Tamir Rashid;Sebastien Corbineau;Nick Hannan;Stefan J. Marciniak

699
Citations
Blood Eosinophils to Direct Corticosteroid Treatment of Exacerbations of Chronic Obstructive Pulmonary Disease: A Randomized Placebo-Controlled Trial

Mona Bafadhel;Susan McKenna;Sarah Terry;Vijay Mistry

688
Citations
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.

Rachael A Evans;Hamish McAuley;Ewen M Harrison;Aarti Shikotra

624
Citations
Alpha1-antitrypsin deficiency--a model for conformational diseases.

Robin W Carrell;David A Lomas

554
Citations
Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease.

Bartolome R. Celli;Nicholas Locantore;Julie Yates;Ruth Tal-Singer

518
Citations
Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort.

Joy Miller;Lisa D Edwards;Alvar Agustí;Per Bakke

494
Citations
Endoplasmic reticulum dysfunction in neurological disease

Benoit D Roussel;Benoit D Roussel;Antonina J Kruppa;Elena Miranda;Damian C Crowther

472
Citations
Variants in FAM13A are associated with chronic obstructive pulmonary disease

Michael H. Cho;Nadia Boutaoui;Barbara J. Klanderman;Jody S. Sylvia

463
Citations
The Mechanism of Z α1-Antitrypsin Accumulation in the Liver

D A Lomas

0
Citations

Frequent Co-Authors

Edwin K. Silverman Brigham and Women's Hospital

Per Bakke University of Bergen

Ruth Tal-Singer GlaxoSmithKline (United Kingdom)

Jørgen Vestbo University of Manchester

Michael H. Cho Harvard University

Amund Gulsvik University of Bergen

Alvar Agusti University of Barcelona

Emiel F.M. Wouters Maastricht University

William MacNee University of Edinburgh

Peter Lange University of Copenhagen

External Links

Personal website of David A. Lomas

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