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Overview

William MacNee is affiliated with the University of Edinburgh in the United Kingdom and focuses primarily on Medicine, with a specialization in Pulmonary and Respiratory Medicine. Their research contributions also span Cardiology and Cardiovascular Medicine, Physiology, Emergency Medical Services, and Public Health, Environmental and Occupational Health.

Their work frequently addresses Chronic Obstructive Pulmonary Disease (COPD) Research, which is the dominant topic in their portfolio. Other main topics include Respiratory Support and Mechanisms, Asthma and respiratory diseases, Pediatric health and respiratory diseases, Injury Epidemiology and Prevention, Balance, Gait, and Falls Prevention, and Cardiovascular and exercise physiology.

William MacNee has collaborated repeatedly with several researchers in the field. Frequent co-authors include:

  • Ruth Tal-Singer
  • Ian B. Wilkinson
  • Divya Mohan
  • Marie Fisk
  • Charlotte E. Bolton

Their published research appears in multiple specialized journals, including:

  • European Respiratory Journal
  • Age and Ageing
  • Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation
  • PLoS ONE
  • Journal of Nuclear Medicine

Recent papers authored by or involving William MacNee include:

  • Markers of disease activity in COPD: an 8-year mortality study in the ECLIPSE cohort, 2020, European Respiratory Journal
  • Short physical performance battery as a practical tool to assess mortality risk in chronic obstructive pulmonary disease, 2020, Age and Ageing
  • Risk assessment for hospital admission in patients with COPD; a multi-centre UK prospective observational study, 2020, PLoS ONE
  • Short Physical Performance Battery: What Does Each Sub-Test Measure in Patients with Chronic Obstructive Pulmonary Disease?, 2020, Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation
  • Consensus Recommendations on the Use of18F-FDG PET/CT in Lung Disease, 2020, Journal of Nuclear Medicine

The research conducted by William MacNee mainly revolves around chronic respiratory illnesses, especially COPD. Their studies frequently evaluate disease activity markers, mortality risks, hospital admission risks, and performance measurement tools related to COPD management.

Best Publications

  • Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper

    B. R. Celli;W. MacNee;A. Agusti;Antonio R Anzueto

  • Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease

    John R. Hurst;Jørgen Vestbo;Jørgen Vestbo;Antonio Anzueto;Nicholas Locantore

  • Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study.

    Craig A. Poland;Rodger Duffin;Ian Kinloch;Andrew Maynard

  • Particulate air pollution and acute health effects

    A. Seaton;D. Godden;W. MacNee;K. Donaldson

  • Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines.

    David M Brown;Martin R Wilson;William MacNee;Vicki Stone

  • Characterisation of COPD heterogeneity in the ECLIPSE cohort

    Àlvar Agustí;Peter Ma Calverley;Bartolome R Celli;Harvey O Coxson

  • Chronic obstructive pulmonary disease phenotypes: the future of COPD.

    Mei Lan K. Han;Alvar Agusti;Peter M. Calverley;Bartolome R. Celli

  • High-Dose Acetylcysteine in Idiopathic Pulmonary Fibrosis

    Maurits Demedts;Juergen Behr;Roland Buhl;Ulrich Costabel

  • Oxidative stress and regulation of glutathione in lung inflammation

    I Rahman;W MacNee

  • Combustion-derived nanoparticles: A review of their toxicology following inhalation exposure

    Ken Donaldson;Lang Tran;Luis Albert Jimenez;Rodger Duffin

  • Changes in forced expiratory volume in 1 second over time in copd

    Jørgen Vestbo;Jørgen Vestbo;Lisa D. Edwards;Paul D. Scanlon;Julie C. Yates

  • Outcomes for COPD pharmacological trials: From lung function to biomarkers

    M. Cazzola;W. MacNee;F.J. Martinez;K.F. Rabe

  • Systemic oxidative stress in asthma, COPD, and smokers.

    I Rahman;D Morrison;K Donaldson;W MacNee

  • Ultrafine (nanometre) particle mediated lung injury

    K Donaldson;X.Y Li;W MacNee

  • Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype.

    Alvar Agustí;Lisa D. Edwards;Stephen I. Rennard;William MacNee

  • Adverse cardiovascular effects of air pollution

    Nicholas L Mills;Ken Donaldson;Paddy W Hadoke;Nicholas A Boon

  • Ambient particle inhalation and the cardiovascular system: potential mechanisms.

    Ken Donaldson;Vicki Stone;Anthony Seaton;William MacNee

  • Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE).

    J Vestbo;W Anderson;H O Coxson;C Crim

  • Pathogenesis of chronic obstructive pulmonary disease.

    William MacNee

  • Oxidative stress and lung inflammation in airways disease.

    William MacNee

Frequent Co-Authors

Ken Donaldson
Ken Donaldson University of Edinburgh
Ruth Tal-Singer
Ruth Tal-Singer GlaxoSmithKline (United Kingdom)
Alvar Agusti
Alvar Agusti University of Barcelona
Jørgen Vestbo
Jørgen Vestbo University of Manchester
Emiel F.M. Wouters
Emiel F.M. Wouters Maastricht University
Irfan Rahman
Irfan Rahman University of Rochester
David A. Lomas
David A. Lomas University College London
Bartolome R. Celli
Bartolome R. Celli Brigham and Women's Hospital
Peter M.A. Calverley
Peter M.A. Calverley University of Liverpool
Harvey O. Coxson
Harvey O. Coxson University of British Columbia

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