World's Best Scientists 2026 revealed!
Alexander F. Schier

Alexander F. Schier

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Molecular Biology
Switzerland
2026

D-Index & Metrics

Molecular Biology

D-Index
112
Citations
52855
World Ranking
339
National Ranking
5

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Switzerland Leader Award
  • 2025 - Research.com Molecular Biology in Switzerland Leader Award
  • 2023 - Research.com Molecular Biology in Switzerland Leader Award
  • 2020 - Member of Academia Europaea
  • 2020 - Member of the National Academy of Sciences
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Alexander F. Schier is affiliated with the University of Basel in Switzerland. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions to molecular biology and cell biology. Additional areas of study include ecology, nature and landscape conservation, and physiology.

Their scientific work concentrates on key topics such as single-cell and spatial transcriptomics, zebrafish biomedical research applications, pluripotent stem cell research, congenital heart defects research, developmental biology and gene regulation, RNA research and splicing, as well as CRISPR and genetic engineering.

Frequent publication venues for their research include bioRxiv (Cold Spring Harbor Laboratory), Cell, Nature Ecology & Evolution, Current Biology, and Developmental Cell.

  • Lucia Y. Du
  • Jialin Liu
  • Adam N. Carte
  • Maxwell E. R. Shafer
  • Jay Shendure

Recent papers authored or co-authored by Alexander F. Schier include the following:

  • Cerebellar Neurodynamics Predict Decision Timing and Outcome on the Single-Trial Level, 2020, Cell
  • A single-cell time-lapse of mouse prenatal development from gastrula to birth, 2024, Nature
  • Emergence of Neuronal Diversity during Vertebrate Brain Development, 2020, Neuron
  • Single-cell biology: beyond the sum of its parts, 2020, Nature Methods
  • Gene family evolution underlies cell-type diversification in the hypothalamus of teleosts, 2021, Nature Ecology & Evolution

Alexander F. Schier's recognitions include membership in various scientific academies and organizations:

  • Member of Academia Europaea, 2020
  • Member of the National Academy of Sciences, 2020
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Spatial reconstruction of single-cell gene expression data

    Rahul Satija;Jeffrey A Farrell;David Gennert;Alexander F Schier

  • Zebrafish MiR-430 Promotes Deadenylation and Clearance of Maternal mRNAs

    Antonio J. Giraldez;Yuichiro Mishima;Jason Rihel;Russell J. Grocock

  • A genetic screen for mutations affecting embryogenesis in zebrafish

    Wolfgang Driever;Lilianna Solnica-Krezel;Alexander F. Schier;Stephan C.F. Neuhauss

  • MicroRNAs Regulate Brain Morphogenesis in Zebrafish

    Antonio J. Giraldez;Ryan M. Cinalli;Margaret E. Glasner;Anton J. Enright

  • Homeodomain-DNA recognition

    Walter J. Gehring;Yan Qiu Qian;Martin Billeter;Katsuo Furukubo-Tokunaga

  • Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs

    James A. Gagnon;Eivind Valen;Summer B. Thyme;Peng Huang;Peng Huang

  • Nodal signaling in vertebrate development.

    Alexander F. Schier

  • The EGF-CFC Protein One-Eyed Pinhead Is Essential for Nodal Signaling

    Kira Gritsman;Jiaojiao Zhang;Simon Cheng;Elizabeth Heckscher

  • Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis

    Andrea Pauli;Eivind Valen;Michael F. Lin;Manuel Garber

  • Zebrafish organizer development and germ-layer formation require nodal-related signals

    Benjamin Feldman;Michael A. Gates;Elizabeth S. Egan;Scott T. Dougan

  • Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis

    Jeffrey A. Farrell;Yiqun Wang;Samantha J. Riesenfeld;Karthik Shekhar

  • Whole-organism lineage tracing by combinatorial and cumulative genome editing

    Aaron McKenna;Gregory M. Findlay;James A. Gagnon;Marshall S. Horwitz

  • Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis

    Albrecht G. Kramer-Zucker;Felix Olale;Courtney J. Haycraft;Bradley K. Yoder

  • Non-coding RNAs as regulators of embryogenesis

    Andrea Pauli;John L. Rinn;John L. Rinn;Alexander F. Schier

  • Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo.

    Didier Y.R. Stainier;Bernadette Fouquet;Jau Nian Chen;Kerri S. Warren

  • Morphogen Gradients: From Generation to Interpretation

    Katherine W. Rogers;Alexander F. Schier

  • Nodal signalling in vertebrate development

    Alexander F. Schier;Michael M. Shen

  • Toddler: an embryonic signal that promotes cell movement via Apelin receptors.

    Andrea Pauli;Megan L. Norris;Eivind Valen;Guo-Liang Chew

  • Efficient recovery of ENU-induced mutations from the zebrafish germline.

    Lilianna Solnica-Krezel;Alexander F. Schier;Wolfgang Driever

  • Molecular Genetics of Axis Formation in Zebrafish

    Alexander F. Schier;William S. Talbot

Frequent Co-Authors

William S. Talbot
William S. Talbot Stanford University
Florian Engert
Florian Engert Harvard University
Lilianna Solnica-Krezel
Lilianna Solnica-Krezel Washington University in St. Louis
Wolfgang Driever
Wolfgang Driever University of Freiburg
Derek L. Stemple
Derek L. Stemple Camena Bioscience
Stephan C.F. Neuhauss
Stephan C.F. Neuhauss University of Zurich
Aviv Regev
Aviv Regev Genentech
Jarema Malicki
Jarema Malicki University of Sheffield
John L. Rinn
John L. Rinn University of Colorado Boulder
Didier Y. R. Stainier
Didier Y. R. Stainier Max Planck Society

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