D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 81 Citations 22,575 194 World Ranking 1628 National Ranking 941

Research.com Recognitions

Awards & Achievements

2018 - Member of the National Academy of Sciences

1995 - Hellman Fellow

1993 - Fellow of Alfred P. Sloan Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • DNA
  • Neuron

Ehud Y. Isacoff mainly focuses on Biophysics, Ion channel, Neuroscience, Gating and Shaker. His Biophysics research is multidisciplinary, incorporating elements of Biochemistry, Patch clamp, Fluorescence and Transmembrane protein. His Ion channel research incorporates elements of Ionotropic glutamate receptor, Stereochemistry and Binding site.

His research in Binding site tackles topics such as Allosteric enzyme which are related to areas like Cell biology. His Neuroscience research includes elements of Glutamate receptor, Glutamatergic, Signaling proteins and Anatomy. His Gating study incorporates themes from Protein structure, Voltage clamp, Membrane potential and Analytical chemistry.

His most cited work include:

  • A Selective Turn-On Fluorescent Sensor for Imaging Copper in Living Cells (643 citations)
  • Light-activated ion channels for remote control of neuronal firing. (588 citations)
  • Direct Physical Measure of Conformational Rearrangement Underlying Potassium Channel Gating (510 citations)

What are the main themes of his work throughout his whole career to date?

Ehud Y. Isacoff mostly deals with Biophysics, Neuroscience, Ion channel, Cell biology and Biochemistry. His Biophysics research includes themes of Receptor and Metabotropic glutamate receptor. His Neuroscience research integrates issues from Glutamate receptor, Neurotransmission and Anatomy.

His Glutamate receptor study deals with Biological neural network intersecting with Premovement neuronal activity. His biological study deals with issues like Photoswitch, which deal with fields such as Stereochemistry and Ligand. Ehud Y. Isacoff interconnects HEK 293 cells, Endogeny and Membrane protein in the investigation of issues within Cell biology.

He most often published in these fields:

  • Biophysics (53.71%)
  • Neuroscience (70.00%)
  • Ion channel (38.00%)

What were the highlights of his more recent work (between 2015-2021)?

  • Neuroscience (70.00%)
  • Biophysics (53.71%)
  • Cell biology (36.57%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Neuroscience, Biophysics, Cell biology, G protein-coupled receptor and Receptor. He studies Neuroscience, namely Optogenetics. His work deals with themes such as Biochemistry, Cooperativity, Ion channel and Class C GPCR, which intersect with Biophysics.

His Ion channel research is multidisciplinary, relying on both Synapse and Second messenger system. His work on Endoplasmic reticulum as part of general Cell biology study is frequently connected to Epithelial sodium channel, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. Ehud Y. Isacoff has researched Receptor in several fields, including Photoswitch and Intracellular.

Between 2015 and 2021, his most popular works were:

  • Molecular basis for multimerization in the activation of the epidermal growth factor receptor (85 citations)
  • Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors (79 citations)
  • Input-Specific Plasticity and Homeostasis at the Drosophila Larval Neuromuscular Junction. (75 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • DNA
  • Biochemistry

Ehud Y. Isacoff focuses on Neuroscience, Biochemistry, Metaplasticity, Synaptic scaling and Nonsynaptic plasticity. His studies in Neuroscience integrate themes in fields like Therapeutic strategy and Dorsal raphe nucleus. His work carried out in the field of Biochemistry brings together such families of science as Biophysics and Calcium channel.

The various areas that he examines in his Biophysics study include G protein-coupled receptor, Metabotropic glutamate receptor, Class C GPCR, Metabotropic glutamate receptor 2 and ORAI1. The study incorporates disciplines such as Glutamatergic and Excitatory postsynaptic potential in addition to Metaplasticity. Ehud Y. Isacoff focuses mostly in the field of Ionotropic glutamate receptor, narrowing it down to matters related to Cell biology and, in some cases, Retinitis pigmentosa.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Light-activated ion channels for remote control of neuronal firing.

Matthew Banghart;Katharine Borges;Ehud Isacoff;Dirk Trauner.
Nature Neuroscience (2004)

833 Citations

A Selective Turn-On Fluorescent Sensor for Imaging Copper in Living Cells

Li Zeng;Evan W. Miller;Arnd Pralle;Ehud Y. Isacoff.
Journal of the American Chemical Society (2006)

803 Citations

Direct Physical Measure of Conformational Rearrangement Underlying Potassium Channel Gating

Lidia M. Mannuzzu;Mario M. Moronne;Ehud Y. Isacoff.
Science (1996)

782 Citations

Subunit counting in membrane-bound proteins.

Maximilian H Ulbrich;Ehud Y Isacoff.
Nature Methods (2007)

773 Citations

Neurexin mediates the assembly of presynaptic terminals.

Camin Dean;Francisco G Scholl;Jenny Choih;Shannon DeMaria.
Nature Neuroscience (2003)

662 Citations

Allosteric control of an ionotropic glutamate receptor with an optical switch.

Matthew Volgraf;Pau Gorostiza;Rika Numano;Rika Numano;Richard H Kramer;Richard H Kramer.
Nature Chemical Biology (2006)

630 Citations

Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes.

Ehud Y. Isacoff;Yuh Nung Jan;Lily Yeh Jan.
Nature (1990)

630 Citations

A selective, cell-permeable optical probe for hydrogen peroxide in living cells.

Michelle C. Y. Chang;Arnd Pralle;Ehud Y. Isacoff;Christopher J. Chang.
Journal of the American Chemical Society (2004)

598 Citations

Transmembrane Movement of the Shaker K+ Channel S4

H.Peter Larsson;Oliver S. Baker;Dalvinder S. Dhillon;Ehud Y. Isacoff.
Neuron (1996)

585 Citations

Boronate-Based Fluorescent Probes for Imaging Cellular Hydrogen Peroxide

Evan W Miller;Aaron E Albers;Arnd Pralle;Ehud Y Isacoff.
Journal of the American Chemical Society (2005)

550 Citations

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