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Chemistry

D-Index
86
Citations
28012
World Ranking
2517
National Ranking
881

Research.com Recognitions

  • 2004 - Fellow of Alfred P. Sloan Foundation
  • 2002 - Hellman Fellow

Overview

Dirk Trauner is a researcher affiliated with the University of Pennsylvania in the United States. Their scientific work spans the fields of Biochemistry, Genetics and Molecular Biology, and Chemistry, with a notable focus on molecular and organic chemistry as well as cellular and molecular neuroscience and pharmacology.

Their primary research areas cover a range of specialized topics, including:

  • Photochromic and Fluorescence Chemistry
  • Photoreceptor and Optogenetics Research
  • Click Chemistry and Applications
  • Chemical Synthesis and Analysis
  • Synthetic Organic Chemistry Methods
  • Carbohydrate Chemistry and Synthesis
  • Chemical Synthesis and Alkaloids

Among frequently published journals, Trauner has significant contributions to:

  • Synfacts
  • Journal of the American Chemical Society
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Cambridge Structural Database
  • Angewandte Chemie International Edition

Their recent notable publications include:

  • "PHOTACs enable optical control of protein degradation," 2020, Science Advances
  • "Computational Design and Synthesis of a Deeply Red-Shifted and Bistable Azobenzene," 2020, Journal of the American Chemical Society
  • "Microtubules control cellular shape and coherence in amoeboid migrating cells," 2020, The Journal of Cell Biology
  • "Optical Manipulation of F-Actin with Photoswitchable Small Molecules," 2020, Journal of the American Chemical Society
  • "Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton," 2020, Nature Communications

Frequent collaborators in their work include Johannes Morstein, Klaus-Peter Ruehmann, Anna C. Impastato, Christopher J. Arp, and A. Novák, reflecting a multidisciplinary and collaborative research approach.

Throughout their career, Trauner has received recognition such as the Fellow of Alfred P. Sloan Foundation award in 2004 and was named a Hellman Fellow in 2002.

Best Publications

  • The B-alkyl Suzuki-Miyaura cross-coupling reaction: Development, mechanistic study, and applications in natural product synthesis

    Sherry R. Chemler;Dirk Trauner;Samuel J. Danishefsky

  • Light-activated ion channels for remote control of neuronal firing.

    Matthew Banghart;Katharine Borges;Ehud Isacoff;Dirk Trauner

  • In Vivo Photopharmacology.

    Katharina Hüll;Johannes Morstein;Dirk Trauner

  • A Roadmap to Success in Photopharmacology

    Johannes Broichhagen;James Allen Frank;Dirk Trauner

  • Allosteric control of an ionotropic glutamate receptor with an optical switch.

    Matthew Volgraf;Pau Gorostiza;Rika Numano;Rika Numano;Richard H Kramer;Richard H Kramer

  • Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose

    Natalie R. Johnston;Ryan K. Mitchell;Elizabeth Haythorne;Maria Paiva Pessoa

  • Reversible photomechanical switching of individual engineered molecules at a metallic surface.

    Matthew J. Comstock;Matthew J. Comstock;Niv Levy;Niv Levy;Armen Kirakosian;Armen Kirakosian;Jongweon Cho;Jongweon Cho

  • Optogenetic dissection of a behavioural module in the vertebrate spinal cord

    Claire Wyart;Filippo Del Bene;Erica Warp;Ethan K. Scott;Ethan K. Scott

  • Extraction of photogenerated electrons and holes from a covalent organic framework integrated heterojunction.

    Mona Calik;Florian Auras;Laura M. Salonen;Kathrin Bader

  • Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death

    Malgorzata Borowiak;Malgorzata Borowiak;Wallis Nahaboo;Martin Reynders;Katharina Nekolla

  • Remote Control of Neuronal Activity with a Light-Gated Glutamate Receptor

    Stephanie Szobota;Pau Gorostiza;Filippo Del Bene;Claire Wyart

  • Biosynthetic and biomimetic electrocyclizations.

    Christopher M. Beaudry;Jeremiah P. Malerich;Dirk Trauner

  • Photochemical control of endogenous ion channels and cellular excitability

    Doris L Fortin;Matthew R Banghart;Timothy W Dunn;Katharine Borges

  • Photochemical Restoration of Visual Responses in Blind Mice

    Aleksandra Polosukhina;Jeffrey Litt;Ivan Tochitsky;Joseph Nemargut

  • PHOTACs enable optical control of protein degradation.

    Martin Reynders;Martin Reynders;Bryan S. Matsuura;Marleen Bérouti;Marleen Bérouti;Daniele Simoneschi

  • Photochromic Blockers of Voltage‐Gated Potassium Channels

    Matthew R. Banghart;Alexandre Mourot;Doris L. Fortin;Jennifer Z. Yao

  • A red-shifted, fast-relaxing azobenzene photoswitch for visible light control of an ionotropic glutamate receptor.

    Michael A. Kienzler;Andreas Reiner;Eric Trautman;Stan Yoo

  • Enantioselective Nazarov Reactions through Catalytic Asymmetric Proton Transfer

    Guangxin Liang;Dirk Trauner

  • Optical control of metabotropic glutamate receptors

    Joshua Levitz;Carlos Pantoja;Benjamin Gaub;Harald Janovjak;Harald Janovjak

  • DieB-Alkyl-Suzuki-Miyaura-Kreuzkupplung: Entwicklung, Untersuchungen zum Mechanismus und Anwendungen in der Naturstoffsynthese

    Sherry R. Chemler;Dirk Trauner;Samuel J. Danishefsky

  • Optochemical genetics.

    Unknown

Frequent Co-Authors

Ehud Y. Isacoff
Ehud Y. Isacoff University of California, Berkeley
Richard H. Kramer
Richard H. Kramer University of California, Berkeley
Peter Mayer
Peter Mayer Ludwig-Maximilians-Universität München
Johann Mulzer
Johann Mulzer University of Vienna
John G. Flannery
John G. Flannery University of California, Berkeley
Guy A. Rutter
Guy A. Rutter Imperial College London
Jan W. Bats
Jan W. Bats Goethe University Frankfurt
Rolf Müller
Rolf Müller Saarland University
Carsten Schultz
Carsten Schultz Oregon Health & Science University
Xiang Zhang
Xiang Zhang University of Hong Kong

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