Guy A. Rutter

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
• 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
• 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award

Overview

Best Publications

• Regulation of mitochondrial ATP synthesis by calcium: Evidence for a long-term metabolic priming

  Laurence S. Jouaville;Paolo Pinton;Carlo Bastianutto;Guy A. Rutter

  962
  Citations

• Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

  Daniel A. Cunha;Paul Hekerman;Laurence Ladrière;Angie Bazarra-Castro

  706
  Citations

• The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus.

  Philipp A. Gerber;Guy A. Rutter

  591
  Citations

• Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing

  N Sekine;V Cirulli;R Regazzi;L J Brown

  517
  Citations

• Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose

  Natalie R. Johnston;Ryan K. Mitchell;Elizabeth Haythorne;Maria Paiva Pessoa

  497
  Citations

• Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis.

  Jan L Vinkenborg;Tamara J Nicolson;Elisa A Bellomo;Melissa S Koay

  465
  Citations

• Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

  Tamara J. Nicolson;Elisa A. Bellomo;Nadeeja Wijesekara;Merewyn K. Loder

  443
  Citations

• INTEGRATING CYTOSOLIC CALCIUM SIGNALS INTO MITOCHONDRIAL METABOLIC RESPONSES

  Lawrence D. Robb‐Gaspers;Paul Burnett;Guy A. Rutter;Richard M. Denton

  437
  Citations

• Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis.

  Guy A. Rutter;Gabriela da Silva Xavier;Isabelle Leclerc

  432
  Citations

• MicroRNA-124a Regulates Foxa2 Expression and Intracellular Signaling in Pancreatic β-Cell Lines

  Nadine Baroukh;Magalie A. Ravier;Merewyn K. Loder;Elaine V. Hill

  414
  Citations

• Mitochondrial calcium as a key regulator of mitochondrial ATP production in mammalian cells.

  Elinor J. Griffiths;Guy A. Rutter

  400
  Citations

• Metformin activates a duodenal Ampk-dependent pathway to lower hepatic glucose production in rats.

  Frank A Duca;Clémence D Côté;Brittany A Rasmussen;Melika Zadeh-Tahmasebi

  398
  Citations

• Pancreatic β-Cell Identity, Glucose Sensing and the Control of Insulin Secretion

  Guy A. Rutter;Timothy J. Pullen;David J. Hodson;Aida Martinez-Sanchez

  384
  Citations

• Regulation of ATP production by mitochondrial Ca2

  Andrei I. Tarasov;Elinor J. Griffiths;Guy A. Rutter

  374
  Citations

• Glucose generates sub-plasma membrane ATP microdomains in single islet beta-cells. Potential role for strategically located mitochondria.

  Helen J. Kennedy;Aristea E. Pouli;Edward K. Ainscow;Laurence S. Jouaville

  373
  Citations

• Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

  N. Wijesekara;F. F. Dai;A. B. Hardy;P. R. Giglou

  361
  Citations

• Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.

  K. Lemaire;M. A. Ravier;A. Schraenen;J. W. M. Creemers

  346
  Citations

• Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression

  Gabriela da Silva Xavier;Isabelle Leclerc;Aniko Varadi;Takashi Tsuboi

  324
  Citations

• Glucose or Insulin, but not Zinc Ions, Inhibit Glucagon Secretion From Mouse Pancreatic α-Cells

  Magalie A. Ravier;Guy A. Rutter

  313
  Citations

• Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1

  Aniko Varadi;Linda I. Johnson-Cadwell;Vincenzo Cirulli;Yisang Yoon

  305
  Citations