D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 85 Citations 21,415 303 World Ranking 1362 National Ranking 83

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Guy A. Rutter mainly investigates Internal medicine, Endocrinology, Cell biology, Insulin and Cytosol. His research on Internal medicine frequently connects to adjacent areas such as AMPK. His Cell biology study incorporates themes from Exocytosis, Vesicle, Secretory Vesicle and Cell.

His Insulin research is multidisciplinary, relying on both Diabetes mellitus, Gene silencing and Homeostasis. The various areas that Guy A. Rutter examines in his Cytosol study include Luciferase, Biophysics, Mitochondrion and Intracellular. His research integrates issues of Myocyte and Stimulation in his study of Biochemistry.

His most cited work include:

  • Regulation of mitochondrial ATP synthesis by calcium: Evidence for a long-term metabolic priming (619 citations)
  • Initiation and execution of lipotoxic ER stress in pancreatic beta-cells. (457 citations)
  • INTEGRATING CYTOSOLIC CALCIUM SIGNALS INTO MITOCHONDRIAL METABOLIC RESPONSES (326 citations)

What are the main themes of his work throughout his whole career to date?

Guy A. Rutter focuses on Internal medicine, Endocrinology, Cell biology, Insulin and Biochemistry. The Internal medicine study combines topics in areas such as AMPK and Protein kinase A. His study in Islet, Glucose homeostasis, Type 2 diabetes, Diabetes mellitus and Beta cell is done as part of Endocrinology.

His studies examine the connections between Cell biology and genetics, as well as such issues in Cytosol, with regards to Depolarization. As part of one scientific family, he deals mainly with the area of Insulin, narrowing it down to issues related to the Gene expression, and often Transcription factor and Molecular biology. As part of his studies on Biochemistry, Guy A. Rutter frequently links adjacent subjects like Biophysics.

He most often published in these fields:

  • Internal medicine (42.32%)
  • Endocrinology (41.91%)
  • Cell biology (38.17%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (38.17%)
  • Endocrinology (41.91%)
  • Internal medicine (42.32%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Endocrinology, Internal medicine, Insulin and Islet. His work on Mitochondrion and Function as part of general Cell biology research is frequently linked to Population, bridging the gap between disciplines. His Mitochondrion study frequently draws connections between adjacent fields such as Cytosol.

His Endocrinology research includes themes of Receptor and In vivo. His research in Insulin intersects with topics in Gene expression, Dense core granule, Agonist, Beta and Type 2 diabetes. The study incorporates disciplines such as Cell, Transcriptome and Secretion in addition to Islet.

Between 2017 and 2021, his most popular works were:

  • Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes. (66 citations)
  • Targeting GLP-1 receptor trafficking to improve agonist efficacy (65 citations)
  • Leader β-cells coordinate Ca2+ dynamics across pancreatic islets in vivo. (47 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Guy A. Rutter spends much of his time researching Cell biology, Islet, Insulin, Type 2 diabetes and Endocrinology. His studies in Cell biology integrate themes in fields like Cell and Receptor. His Islet study combines topics in areas such as Cell culture and Gene expression.

His research investigates the connection between Insulin and topics such as Transcriptome that intersect with issues in Pathogenesis. Guy A. Rutter has researched Type 2 diabetes in several fields, including Glucokinase and Beta cell. His Endocrinology study frequently intersects with other fields, such as Internal medicine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Regulation of mitochondrial ATP synthesis by calcium: Evidence for a long-term metabolic priming

Laurence S. Jouaville;Paolo Pinton;Carlo Bastianutto;Guy A. Rutter.
Proceedings of the National Academy of Sciences of the United States of America (1999)

823 Citations

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

Daniel A. Cunha;Paul Hekerman;Laurence Ladrière;Angie Bazarra-Castro.
Journal of Cell Science (2008)

613 Citations

Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis.

Guy A. Rutter;Gabriela da Silva Xavier;Isabelle Leclerc.
Biochemical Journal (2003)

414 Citations

INTEGRATING CYTOSOLIC CALCIUM SIGNALS INTO MITOCHONDRIAL METABOLIC RESPONSES

Lawrence D. Robb‐Gaspers;Paul Burnett;Guy A. Rutter;Richard M. Denton.
The EMBO Journal (1998)

401 Citations

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

Tamara J. Nicolson;Elisa A. Bellomo;Nadeeja Wijesekara;Merewyn K. Loder.
Diabetes (2009)

390 Citations

Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis.

Jan L Vinkenborg;Tamara J Nicolson;Elisa A Bellomo;Melissa S Koay.
Nature Methods (2009)

383 Citations

MicroRNA-124a Regulates Foxa2 Expression and Intracellular Signaling in Pancreatic β-Cell Lines

Nadine Baroukh;Magalie A. Ravier;Merewyn K. Loder;Elaine V. Hill.
Journal of Biological Chemistry (2007)

379 Citations

Glucose generates sub-plasma membrane ATP microdomains in single islet beta-cells. Potential role for strategically located mitochondria.

Helen J. Kennedy;Aristea E. Pouli;Edward K. Ainscow;Laurence S. Jouaville.
Journal of Biological Chemistry (1999)

342 Citations

Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression

Gabriela da Silva Xavier;Isabelle Leclerc;Aniko Varadi;Takashi Tsuboi.
Biochemical Journal (2003)

314 Citations

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.

K. Lemaire;M. A. Ravier;A. Schraenen;J. W. M. Creemers.
Proceedings of the National Academy of Sciences of the United States of America (2009)

304 Citations

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