2023 - Research.com Medicine in Belgium Leader Award
The scientist’s investigation covers issues in Internal medicine, Endocrinology, Pancreatic islets, Cell biology and Cytokine. His Internal medicine study frequently draws connections between adjacent fields such as Apoptosis. His Endocrinology research includes themes of Unfolded protein response and Endoplasmic reticulum.
His Pancreatic islets research incorporates themes from Promoter, Methylation and Insulitis. The various areas that he examines in his Cell biology study include Citric acid cycle and Alternative splicing. Decio L. Eizirik combines subjects such as Molecular biology, Regulation of gene expression, Transcription factor and Gene expression with his study of Cytokine.
Decio L. Eizirik mainly investigates Internal medicine, Endocrinology, Pancreatic islets, Cell biology and Islet. Decio L. Eizirik usually deals with Internal medicine and limits it to topics linked to Diabetes mellitus and Immunology. His study in Endocrinology is interdisciplinary in nature, drawing from both Apoptosis and Cytokine.
His Pancreatic islets study also includes fields such as
His scientific interests lie mostly in Beta cell, Cell biology, Pancreatic islets, Islet and Beta. His Beta cell research is multidisciplinary, incorporating elements of Inflammation, Unfolded protein response, Apoptosis and Immune system. His Cell biology study combines topics from a wide range of disciplines, such as Cytokine, Transcriptome, Transcription factor, Exon and SUMO protein.
His Pancreatic islets research is multidisciplinary, incorporating perspectives in Cancer research, Pancreas, Receptor, Messenger RNA and Antibody. His studies in Islet integrate themes in fields like Molecular biology, Downregulation and upregulation, Gene expression and Type 2 diabetes. His work carried out in the field of Endoplasmic reticulum brings together such families of science as Endocrinology, Neurodegeneration, Internal medicine and Microcephaly.
His primary scientific interests are in Beta cell, Pancreatic islets, Cell biology, Cancer research and Proinflammatory cytokine. His Beta cell research includes elements of Propidium iodide, Inflammation, Immune system, MHC class I and Unfolded protein response. The study incorporates disciplines such as Antibody and NOD mice in addition to Pancreatic islets.
Decio L. Eizirik interconnects Gene expression, RNA, Transcription factor, Beta and Translation in the investigation of issues within Cell biology. His work in Cancer research addresses issues such as Cell, which are connected to fields such as Secretion and Endoplasmic reticulum. His Endoplasmic reticulum research incorporates elements of Internal medicine and Endocrinology.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities.
Miriam Cnop;Nils Welsh;Jean-Christophe Jonas;Anne Jörns.
Diabetes (2005)
The role for endoplasmic reticulum stress in diabetes mellitus.
Décio L. Eizirik;Alessandra K. Cardozo;Miriam Cnop;Miriam Cnop.
Endocrine Reviews (2008)
A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis
Decio L. Eizirik;T. Mandrup-Poulsen.
Diabetologia (2001)
The role of inflammation in insulitis and beta-cell loss in type 1 diabetes.
Decio L. Eizirik;Maikel Luis Colli;Fernanda Ortis.
Nature Reviews Endocrinology (2009)
Free Fatty Acids and Cytokines Induce Pancreatic β-Cell Apoptosis by Different Mechanisms: Role of Nuclear Factor-κB and Endoplasmic Reticulum Stress
Ilham Kharroubi;Laurence Ladrière;Alessandra K Cardozo;Zeynep Dogusan.
Endocrinology (2004)
Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.
Miriam Cnop;Jean Claude Hannaert;Anne Hoorens;Décio L. Eizirik.
Diabetes (2001)
Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca2+ ATPase 2b and Deplete Endoplasmic Reticulum Ca2+, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells
Alessandra K. Cardozo;Fernanda Ortis;Joachim Storling;Ying-Mei Feng.
Diabetes (2005)
Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.
Daniel A. Cunha;Paul Hekerman;Laurence Ladrière;Angie Bazarra-Castro.
Journal of Cell Science (2008)
Interleukin-lβ-Induced Nitric Oxide Production in Isolated Rat Pancreatic Islets Requires Gene Transcription and May Lead to Inhibition of the Krebs Cycle Enzyme Aconitase
Nils Welsh;Decio L. Eizirik;Klaus Bendtzen;Stellan Sandler.
Endocrinology (1991)
Cytokines Induce Deoxyribonucleic Acid Strand Breaks and Apoptosis in Human Pancreatic Islet Cells
Carol A. Delaney;Dejan Pavlovic;Anne Hoorens;Daniel G. Pipeleers.
Endocrinology (1997)
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